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Chemical Compound Review

Probanthine     methyl-dipropan-2-yl-[2-(9H- xanthen-9...

Synonyms: Propanthel, propantheline, Propanthelinum, Prestwick_241, Lopac-P-8891, ...
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Disease relevance of propantheline


High impact information on propantheline


Chemical compound and disease context of propantheline


Biological context of propantheline


Anatomical context of propantheline


Associations of propantheline with other chemical compounds


Gene context of propantheline


Analytical, diagnostic and therapeutic context of propantheline


  1. Effect of low-dose propantheline on food-stimulated gastric acid secretion: comparison with an "optimal effective dose" and interaction with cimetidine. Feldman, M., Richardson, C.T., Peterson, W.L., Walsh, J.H., Fordtran, J.S. N. Engl. J. Med. (1977) [Pubmed]
  2. Cimetidine plus propantheline for chronic pancreatitis. Weinstein, G.S., Dupont, P.J. N. Engl. J. Med. (1978) [Pubmed]
  3. Unilateral mydriasis after use of propantheline bromide in an antiperspirant. Nissen, S.H., Nielsen, P.G. Lancet (1977) [Pubmed]
  4. The effect of cimetidine and propantheline on the symptoms of a patient with systemic mastocytosis. Achord, J.L., Langford, H. Am. J. Med. (1980) [Pubmed]
  5. Prolongation of gastric emptying by oral propantheline. Hurwitz, A., Robinson, R.G., Herrin, W.F. Clin. Pharmacol. Ther. (1977) [Pubmed]
  6. Treatment of hemorrhagic gastritis with 15(R)-15 methyl prostaglandin E2: report of a case. Weiss, J.B., Peskin, G.W., Isenberg, J.I. Gastroenterology (1982) [Pubmed]
  7. Giant hypertrophic gastropathy (Ménétrier's disease): pharmacologic effects on protein leakage and mucosal ultrastructure. Kelly, D.G., Miller, L.J., Malagelada, J.R., Huizenga, K.A., Markowitz, H. Gastroenterology (1982) [Pubmed]
  8. Pharmacological modulation of gastric emptying rate of solids as measured by the carbon labelled octanoic acid breath test: influence of erythromycin and propantheline. Maes, B.D., Hiele, M.I., Geypens, B.J., Rutgeerts, P.J., Ghoos, Y.F., Vantrappen, G. Gut (1994) [Pubmed]
  9. Effects of intravenous and oral propantheline and metoclopramide on ethanol absorption. Gibbons, D.O., Lant, A.F. Clin. Pharmacol. Ther. (1975) [Pubmed]
  10. Oxybutynin versus propantheline in patients with multiple sclerosis and detrusor hyperreflexia. Gajewski, J.B., Awad, S.A. J. Urol. (1986) [Pubmed]
  11. Toxicity studies of amphetamine sulfate, ampicillin trihydrate, codeine, 8-methoxypsoralen, alpha-methyldopa, penicillin VK and propantheline bromide in rats and mice. Dunnick, J.K., Elwell, M.R. Toxicology (1989) [Pubmed]
  12. Urinary urge incontinence: randomised crossover trials of penthienate versus placebo and propantheline. Coombes, G.M., Millard, R.J. Med. J. Aust. (1996) [Pubmed]
  13. Propantheline bromide in the management of hyperhidrosis associated with spinal cord injury. Canaday, B.R., Stanford, R.H. The Annals of pharmacotherapy. (1995) [Pubmed]
  14. Combination of anticholinergic agent and H2 receptor antagonist in duodenal ulcer treatment--a randomized, double blind multicenter study. Agrawal, B.K., Suman, A., Kumar, A., Broor, S.L., Rajasambandam, P., Palaniswamy, K.R., Mohan, A.T., Gupta, J.P. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology. (1993) [Pubmed]
  15. Comparison of two antimuscarinic drugs, pirenzepine and propantheline, on gastric acid secretion, serum gastrin concentration, salivary flow and heart rate in patients with duodenal ulcer disease. Richardson, C.T., Barnett, C.C., Walsh, J.H., Feldman, M. Aliment. Pharmacol. Ther. (1987) [Pubmed]
  16. Randomized, double-blind, multicenter trial on treatment of frequency, urgency and incontinence related to detrusor hyperactivity: oxybutynin versus propantheline versus placebo. Thüroff, J.W., Bunke, B., Ebner, A., Faber, P., de Geeter, P., Hannappel, J., Heidler, H., Madersbacher, H., Melchior, H., Schäfer, W. J. Urol. (1991) [Pubmed]
  17. Comparative studies of the effects of some antimuscarinic agents on gastric damage and pupillary reflex in the rat. Daniotti, S., Del Soldato, P. Br. J. Pharmacol. (1984) [Pubmed]
  18. Food reduces the oral bioavailability of propantheline bromide in healthy subjects. Moses, D.K., Charles, B.G., Ravenscroft, P.J., Whyte, I.M. British journal of clinical pharmacology. (1983) [Pubmed]
  19. A steady-state evaluation of the effects of propantheline bromide and cholestyramine on the bioavailability of digoxin when administered as tablets or capsules. Brown, D.D., Schmid, J., Long, R.A., Hull, J.H. Journal of clinical pharmacology. (1985) [Pubmed]
  20. Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. Hassan, M., Dalton, C.B., Castell, J.A., Castell, D.O. Am. J. Gastroenterol. (1986) [Pubmed]
  21. Propantheline prevention of mucositis from etoposide. Ahmed, T., Engelking, C., Szalyga, J., Helson, L., Coombe, N., Cook, P., Corbi, D., Puccio, C., Chun, H., Mittelman, A. Bone Marrow Transplant. (1993) [Pubmed]
  22. Taurine in submandibular gland of the rat: effect of muscarinic drugs. Mozaffari, M.S., Borke, J.L. J. Histochem. Cytochem. (2002) [Pubmed]
  23. Possible involvement of multiple P-glycoprotein-mediated efflux systems in the transport of verapamil and other organic cations across rat intestine. Saitoh, H., Aungst, B.J. Pharm. Res. (1995) [Pubmed]
  24. Transport characteristics of propantheline across rat intestinal brush border membrane. Saitoh, H., Kawai, S., Miyazaki, K., Arita, T. J. Pharm. Pharmacol. (1988) [Pubmed]
  25. Oral anticholinergics and gastric emptying. Hurwitz, A., Robinson, R.G., Herrin, W.F., Christie, J. Clin. Pharmacol. Ther. (1982) [Pubmed]
  26. Clinical pharmacokinetics of paracetamol. Forrest, J.A., Clements, J.A., Prescott, L.F. Clinical pharmacokinetics. (1982) [Pubmed]
  27. Influence of the pharmacological modification of gastric emptying on lactose digestion and gastrointestinal symptoms. Peuhkuri, K., Vapaatalo, H., Nevala, R., Korpela, R. Aliment. Pharmacol. Ther. (1999) [Pubmed]
  28. Cystometric response to propantheline in detrusor hyperreflexia: therapeutic implications. Blaivas, J.G., Labib, K.B., Michalik, S.J., Zayed, A.A. J. Urol. (1980) [Pubmed]
  29. Effects of propantheline bromide on basal growth hormone, cortisol and prolactin levels. Davis, B.M., Mathé, A.A., Mohs, R.C., Levy, M.I., Davis, K.L. Psychoneuroendocrinology (1983) [Pubmed]
  30. Augmentation ileocystoplasty in neuropathic bladder. Raezer, D.M., Evans, R.J., Shrom, S.H. Urology (1985) [Pubmed]
  31. Gastric mucosal damage in rats induced by lateral hypothalamic lesions: protection by propantheline, cimetidine, and vagotomy. Grijalva, C.V., Deregnaucourt, J., Code, C.F., Novin, D. Proc. Soc. Exp. Biol. Med. (1980) [Pubmed]
  32. Analysis of propantheline bromide in serum by high-performance liquid chromatography. Charles, B.G., Ravenscroft, P.J., Jacobsen, N.W. J. Chromatogr. (1984) [Pubmed]
  33. Propantheline as an adjuvant to weight loss after vertical gastroplasty. Jamieson, A.C. Obesity surgery : the official journal of the American Society for Bariatric Surgery and of the Obesity Surgery Society of Australia and New Zealand. (1997) [Pubmed]
  34. Propantheline protects the oral mucosa after high-dose ifosfamide, carboplatin, etoposide and autologous stem cell transplantation. Oblon, D.J., Paul, S.R., Oblon, M.B., Malik, S. Bone Marrow Transplant. (1997) [Pubmed]
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