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Chemical Compound Review

gamma-Tocotrienol     (2R)-2,7,8-trimethyl-2- (4,8,12...

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Disease relevance of gamma-Tocotrienol


High impact information on gamma-Tocotrienol


Biological context of gamma-Tocotrienol


Anatomical context of gamma-Tocotrienol


Associations of gamma-Tocotrienol with other chemical compounds


Gene context of gamma-Tocotrienol


Analytical, diagnostic and therapeutic context of gamma-Tocotrienol


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  3. Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. Conte, C., Floridi, A., Aisa, C., Piroddi, M., Floridi, A., Galli, F. Ann. N. Y. Acad. Sci. (2004) [Pubmed]
  4. Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells. Sakai, M., Okabe, M., Tachibana, H., Yamada, K. J. Nutr. Biochem. (2006) [Pubmed]
  5. Tocotrienol and fatty acid composition of barley oil and their effects on lipid metabolism. Wang, L., Newman, R.K., Newman, C.W., Jackson, L.L., Hofer, P.J. Plant foods for human nutrition (Dordrecht, Netherlands) (1993) [Pubmed]
  6. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Parker, R.A., Pearce, B.C., Clark, R.W., Gordon, D.A., Wright, J.J. J. Biol. Chem. (1993) [Pubmed]
  7. Modulation of Cyp3a11 mRNA expression by alpha-tocopherol but not gamma-tocotrienol in mice. Kluth, D., Landes, N., Pfluger, P., Müller-Schmehl, K., Weiss, K., Bumke-Vogt, C., Ristow, M., Brigelius-Flohé, R. Free Radic. Biol. Med. (2005) [Pubmed]
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  9. Gamma-tocotrienol, a vitamin E homolog, is a natriuretic hormone precursor. Saito, H., Kiyose, C., Yoshimura, H., Ueda, T., Kondo, K., Igarashi, O. J. Lipid Res. (2003) [Pubmed]
  10. A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. Chen, C.W., Cheng, H.H. J. Nutr. (2006) [Pubmed]
  11. Dietary alpha-tocopherol attenuates the impact of gamma-tocotrienol on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in chickens. Qureshi, A.A., Pearce, B.C., Nor, R.M., Gapor, A., Peterson, D.M., Elson, C.E. J. Nutr. (1996) [Pubmed]
  12. Response of hypercholesterolemic subjects to administration of tocotrienols. Qureshi, A.A., Bradlow, B.A., Brace, L., Manganello, J., Peterson, D.M., Pearce, B.C., Wright, J.J., Gapor, A., Elson, C.E. Lipids (1995) [Pubmed]
  13. Effect of gamma-tocotrienol on blood pressure, lipid peroxidation and total antioxidant status in spontaneously hypertensive rats (SHR). Newaz, M.A., Nawal, N.N. Clin. Exp. Hypertens. (1999) [Pubmed]
  14. Intracellular signaling mechanisms mediating the antiproliferative and apoptotic effects of gamma-tocotrienol in neoplastic mammary epithelial cells. Sylvester, P.W., Shah, S.J., Samant, G.V. J. Plant Physiol. (2005) [Pubmed]
  15. Dietary sesame seeds elevate alpha- and gamma-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil. Ikeda, S., Toyoshima, K., Yamashita, K. J. Nutr. (2001) [Pubmed]
  16. Intestinal Epithelial Cells Absorb gamma-Tocotrienol Faster than alpha-Tocopherol. Tsuzuki, W., Yunoki, R., Yoshimura, H. Lipids (2007) [Pubmed]
  17. Comparative effects of alpha-tocopherol and gamma-tocotrienol against hydrogen peroxide induced apoptosis on primary-cultured astrocytes. Mazlan, M., Sue Mian, T., Mat Top, G., Zurinah Wan Ngah, W. J. Neurol. Sci. (2006) [Pubmed]
  18. Comparative antioxidant activity of tocotrienols and the novel chromanyl-polyisoprenyl molecule FeAox-6 in isolated membranes and intact cells. Palozza, P., Verdecchia, S., Avanzi, L., Vertuani, S., Serini, S., Iannone, A., Manfredini, S. Mol. Cell. Biochem. (2006) [Pubmed]
  19. Vitamin E activates gene expression via the pregnane X receptor. Landes, N., Pfluger, P., Kluth, D., Birringer, M., Rühl, R., Böl, G.F., Glatt, H., Brigelius-Flohé, R. Biochem. Pharmacol. (2003) [Pubmed]
  20. Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin. Traber, M.G., Rallis, M., Podda, M., Weber, C., Maibach, H.I., Packer, L. Lipids (1998) [Pubmed]
  21. Induction of cytokines by radioprotective tocopherol analogs. Singh, V.K., Shafran, R.L., Jackson, W.E., Seed, T.M., Kumar, K.S. Exp. Mol. Pathol. (2006) [Pubmed]
  22. gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells. Samant, G.V., Sylvester, P.W. Cell Prolif. (2006) [Pubmed]
  23. Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells. Shah, S., Sylvester, P.W. Exp. Biol. Med. (Maywood) (2004) [Pubmed]
  24. gamma-Tocotrienol as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. Watkins, T., Lenz, P., Gapor, A., Struck, M., Tomeo, A., Bierenbaum, M. Lipids (1993) [Pubmed]
  25. Identification of alpha-, beta-, gamma-, and delta-tocopherols and their contents in human milk. Kobayashi, H., Kanno, C., Yamauchi, K., Tsugo, T. Biochim. Biophys. Acta (1975) [Pubmed]
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