Chemical Compound Review:
Homocarnosine 2-(4-aminobutanoylamino)-3- (3H-imidazol-4...
Synonyms:
CHEBI:28050, NSC-92522, SureCN10937318, AC1L3HFG, AC1Q5SHP, ...
- Bilateral striopallidodentate calcinosis: cerebrospinal fluid, imaging, and electrophysiological studies. Manyam, B.V., Bhatt, M.H., Moore, W.D., Devleschoward, A.B., Anderson, D.R., Calne, D.B. Ann. Neurol. (1992)
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- Neuroprotective effects of carnosine and homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. Tabakman, R., Lazarovici, P., Kohen, R. J. Neurosci. Res. (2002)
- Apoptotic characteristics of cell death and the neuroprotective effect of homocarnosine on pheochromocytoma PC12 cells exposed to ischemia. Tabakman, R., Jiang, H., Levine, R.A., Kohen, R., Lazarovici, P. J. Neurosci. Res. (2004)
- Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Goddard, A.W., Mason, G.F., Almai, A., Rothman, D.L., Behar, K.L., Petroff, O.A., Charney, D.S., Krystal, J.H. Arch. Gen. Psychiatry (2001)
- Human CSF GABA concentrations: revised downward for controls, but not decreased in Huntington's chorea. Perry, T.L., Hansen, S., Wall, R.A., Gauthier, S.G. J. Neurochem. (1982)
- Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain. Kohen, R., Yamamoto, Y., Cundy, K.C., Ames, B.N. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Sequence identification and characterization of human carnosinase and a closely related non-specific dipeptidase. Teufel, M., Saudek, V., Ledig, J.P., Bernhardt, A., Boularand, S., Carreau, A., Cairns, N.J., Carter, C., Cowley, D.J., Duverger, D., Ganzhorn, A.J., Guenet, C., Heintzelmann, B., Laucher, V., Sauvage, C., Smirnova, T. J. Biol. Chem. (2003)
- Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Petroff, O.A., Hyder, F., Rothman, D.L., Mattson, R.H. Neurology (2001)
- Homology modeling of human serum carnosinase, a potential medicinal target, and MD simulations of its allosteric activation by citrate. Vistoli, G., Pedretti, A., Cattaneo, M., Aldini, G., Testa, B. J. Med. Chem. (2006)
- Generation of free radicals from lipid hydroperoxides by Ni2+ in the presence of oligopeptides. Shi, X., Dalal, N.S., Kasprzak, K.S. Arch. Biochem. Biophys. (1992)
- Amino acid metabolism in the brain with convulsive disorders. Part 2: The effects of anticonvulsants on convulsions and free amino acid patterns in the brain of El mouse. Honda, T. Brain Dev. (1984)
- Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo? Aruoma, O.I., Laughton, M.J., Halliwell, B. Biochem. J. (1989)
- Does homocarnosine mediate the dyskinetic movements induced by gaba-transaminase inhibitors. Robin, M.M., Palfreyman, M.G. Neuropharmacology (1982)
- Purification and properties of human serum carnosinase. Jackson, M.C., Kucera, C.M., Lenney, J.F. Clin. Chim. Acta (1991)
- Studies on homocarnosine in cerebrospinal fluid in infancy and childhood. Part I. Homocarnosine level in cerebrospinal fluid of normal infants and children. Takahashi, H. Brain Dev. (1981)
- Metabolism of carnosine and homocarnosine in subcellular fractions and neuronal and glial cell-enriched fractions of rabbit brain. Ng, R.H., Marshall, F.D., Henn, F.A., Sellström, A. J. Neurochem. (1977)
- Homocarnosine and the measurement of neuronal pH in patients with epilepsy. Rothman, D.L., Behar, K.L., Prichard, J.W., Petroff, O.A. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. (1997)
- Inhibition of the growth of transformed and neoplastic cells by the dipeptide carnosine. Holliday, R., McFarland, G.A. Br. J. Cancer (1996)
- Carnosine and homocarnosine, the forgotten, enigmatic peptides of the brain. Bauer, K. Neurochem. Res. (2005)
- Localization of a novel pathway for the liberation of GABA in the human CNS. Jackson, M.C., Scollard, D.M., Mack, R.J., Lenney, J.F. Brain Res. Bull. (1994)
- Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Petroff, O.A., Hyder, F., Mattson, R.H., Rothman, D.L. Neurology (1999)
- Artifactual increases in the concentration of free GABA in samples of human cerebrospinal fluid are due to degradation of homocarnosine. Grove, J., Schechter, P.J., Tell, G., Rumbach, L., Marescaux, C., Warter, J.M., Koch-Weser, J. J. Neurochem. (1982)
- Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species. Boldyrev, A., Song, R., Lawrence, D., Carpenter, D.O. Neuroscience (1999)
- Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics. Mueller, S.G., Weber, O.M., Duc, C.O., Weber, B., Meier, D., Russ, W., Boesiger, P., Wieser, H.G. Epilepsia (2001)
- The ceruloplasmin and hydrogen peroxide system induces alpha-synuclein aggregation in vitro. Kim, K.S., Choi, S.Y., Kwon, H.Y., Won, M.H., Kang, T.C., Kang, J.H. Biochimie (2002)
- Carnosine and related dipeptides protect human ceruloplasmin against peroxyl radical-mediated modification. Kang, J.H., Kim, K.S., Choi, S.Y., Kwon, H.Y., Won, M.H., Kang, T.C. Mol. Cells (2002)
- Total GABA and homocarnosine in CSF as indices of brain GABA concentrations. Palfreyman, M.G., Huot, S., Grove, J. Neurosci. Lett. (1983)
- Concentration gradients of free and total gamma-aminobutyric acid and homocarnosine in human CSF: comparison of suboccipital and lumbar sampling. Grove, J., Schechter, P.J., Hanke, N.F., de Smet, Y., Agid, Y., Tell, G., Koch-Weser, J. J. Neurochem. (1982)
- Determination of ophidine in human urine. Undrum, T., Lunde, H., Gjessing, L.R. J. Chromatogr. (1982)
- Carnosine in the brain and olfactory system of amphibia and reptilia: a comparative study using immunocytochemical and biochemical methods. Artero, C., Martì, E., Biffo, S., Mulatero, B., Andreone, C., Margolis, F.L., Fasolo, A. Neurosci. Lett. (1991)
- Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat. Ziesler, O., Hole, K., Haugan, I., Børresen, A.L., Gjessing, L.R., Sjaastad, O. Neurochem. Res. (1984)