Gene Review:
RAI1 - retinoic acid induced 1
Homo sapiens
Synonyms:
DKFZP434A139, KIAA1820, MGC12824, Retinoic acid-induced protein 1, SMCR, ...
- Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes. Seranski, P., Heiss, N.S., Dhorne-Pollet, S., Radelof, U., Korn, B., Hennig, S., Backes, E., Schmidt, S., Wiemann, S., Schwarz, C.E., Lehrach, H., Poustka, A. Genomics (1999)
- Modulation of age at onset in Huntington's disease and spinocerebellar ataxia type 2 patients originated from eastern India. Chattopadhyay, B., Ghosh, S., Gangopadhyay, P.K., Das, S.K., Roy, T., Sinha, K.K., Jha, D.K., Mukherjee, S.C., Chakraborty, A., Singhal, B.S., Bhattacharya, A.K., Bhattacharyya, N.P. Neurosci. Lett. (2003)
- Genotype-phenotype correlation in Smith-Magenis syndrome: evidence that multiple genes in 17p11.2 contribute to the clinical spectrum. Girirajan, S., Vlangos, C.N., Szomju, B.B., Edelman, E., Trevors, C.D., Dupuis, L., Nezarati, M., Bunyan, D.J., Elsea, S.H. Genet. Med. (2006)
- RAI1 variations in Smith-Magenis syndrome patients without 17p11.2 deletions. Girirajan, S., Elsas, L.J., Devriendt, K., Elsea, S.H. J. Med. Genet. (2005)
- Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma. Thiele, C.J., Reynolds, C.P., Israel, M.A. Nature (1985)
- Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern. König, G., Masters, C.L., Beyreuther, K. FEBS Lett. (1990)
- Critical period for retinoic acid-induced developmental abnormalities of the vitreous in mouse fetuses. Ozeki, H., Shirai, S., Ikeda, K., Ogura, Y. Exp. Eye Res. (1999)
- Mutations in RAI1 associated with Smith-Magenis syndrome. Slager, R.E., Newton, T.L., Vlangos, C.N., Finucane, B., Elsea, S.H. Nat. Genet. (2003)
- Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Altucci, L., Rossin, A., Raffelsberger, W., Reitmair, A., Chomienne, C., Gronemeyer, H. Nat. Med. (2001)
- Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Kawasaki, H., Eckner, R., Yao, T.P., Taira, K., Chiu, R., Livingston, D.M., Yokoyama, K.K. Nature (1998)
- Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Li, Y.S., Milner, P.G., Chauhan, A.K., Watson, M.A., Hoffman, R.M., Kodner, C.M., Milbrandt, J., Deuel, T.F. Science (1990)
- Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation. Hiroi, N., Ito, T., Yamamoto, H., Ochiya, T., Jinno, S., Okayama, H. EMBO J. (2002)
- Integrin phosphorylation is modulated during the differentiation of F-9 teratocarcinoma stem cells. Dahl, S.C., Grabel, L.B. J. Cell Biol. (1989)
- Effects of liarozole, a new antitumoral compound, on retinoic acid-induced inhibition of cell growth and on retinoic acid metabolism in MCF-7 human breast cancer cells. Wouters, W., van Dun, J., Dillen, A., Coene, M.C., Cools, W., De Coster, R. Cancer Res. (1992)
- Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. Li, Y., Hashimoto, Y., Agadir, A., Kagechika, H., Zhang, X. J. Biol. Chem. (1999)
- Transcriptional activation of Gs alpha expression by retinoic acid and parathyroid hormone-related protein in F9 teratocarcinoma cells. Chan, S.D., Strewler, G.J., Nissenson, R.A. J. Biol. Chem. (1990)
- Mutations of RAI1, a PHD-containing protein, in nondeletion patients with Smith-Magenis syndrome. Bi, W., Saifi, G.M., Shaw, C.J., Walz, K., Fonseca, P., Wilson, M., Potocki, L., Lupski, J.R. Hum. Genet. (2004)
- Smith-Magenis syndrome and growth hormone deficiency. Spadoni, E., Colapietro, P., Bozzola, M., Marseglia, G.L., Repossi, L., Danesino, C., Larizza, L., Maraschio, P. Eur. J. Pediatr. (2004)
- RAI1 point mutations, CAG repeat variation, and SNP analysis in non-deletion Smith-Magenis syndrome. Bi, W., Saifi, G.M., Girirajan, S., Shi, X., Szomju, B., Firth, H., Magenis, R.E., Potocki, L., Elsea, S.H., Lupski, J.R. Am. J. Med. Genet. A (2006)
- Appearance of a new nucleosomal protein during differentiation of human leukemia (HL-60) cells. Chou, R.H., Chervenick, P.A., Barch, D.R. Science (1984)
- Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. Williams, T., Admon, A., Lüscher, B., Tjian, R. Genes Dev. (1988)
- Retinoic acid receptor expression vector inhibits differentiation of F9 embryonal carcinoma cells. Espeseth, A.S., Murphy, S.P., Linney, E. Genes Dev. (1989)
- GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells. Resendes, K.K., Rosmarin, A.G. Mol. Cell. Biol. (2006)
- Changing the differentiation program of hematopoietic cells: retinoic acid-induced shift of eosinophil-committed cells to neutrophils. Paul, C.C., Mahrer, S., Tolbert, M., Elbert, B.L., Wong, I., Ackerman, S.J., Baumann, M.A. Blood (1995)
- CAG repeat length in RAI1 is associated with age at onset variability in spinocerebellar ataxia type 2 (SCA2). Hayes, S., Turecki, G., Brisebois, K., Lopes-Cendes, I., Gaspar, C., Riess, O., Ranum, L.P., Pulst, S.M., Rouleau, G.A. Hum. Mol. Genet. (2000)
- Interferon gamma abrogates the differentiation block in v-myc-expressing U-937 monoblasts. Oberg, F., Larsson, L.G., Anton, R., Nilsson, K. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Retinoic acid (vitamin A acid) induced transcriptional control of interferon production. Blalock, J.E., Gifford, G.E. Proc. Natl. Acad. Sci. U.S.A. (1977)
- Involvement of retinoic acid receptor-alpha-mediated signaling pathway in induction of CD38 cell-surface antigen. Mehta, K., McQueen, T., Manshouri, T., Andreeff, M., Collins, S., Albitar, M. Blood (1997)
- Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia. Meng, Y.S., Khoury, H., Dick, J.E., Minden, M.D. Leukemia (2005)
- Retinoic acid-induced apoptosis and regression of a refractory Epstein-Barr virus-containing T cell lymphoma expressing multidrug-resistance phenotypes. Su, I.J., Cheng, A.L., Tsai, T.F., Lay, J.D. Br. J. Haematol. (1993)
- CDK2/4 regulate retinoic acid-induced G1 arrest in hepatocellular carcinoma cells. Jung, H.Y., Park, S.H., Yoo, Y.D., Kim, J.S., Kim, Y.H. Hepatol. Res. (2005)
- FMS (CSF-1 receptor) prolongs cell cycle and promotes retinoic acid-induced hypophosphorylation of retinoblastoma protein, G1 arrest, and cell differentiation. Yen, A., Sturgill, R., Varvayanis, S., Chern, R. Exp. Cell Res. (1996)
- Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. Lamkin, T.J., Chin, V., Varvayanis, S., Smith, J.L., Sramkoski, R.M., Jacobberger, J.W., Yen, A. J. Cell. Biochem. (2006)
- Diagnostic FISH probes for del(17)(p11.2p11.2) associated with Smith-Magenis syndrome should contain the RAI1 gene. Vlangos, C.N., Wilson, M., Blancato, J., Smith, A.C., Elsea, S.H. Am. J. Med. Genet. A (2005)
- Trisomy 17p10-p12 due to mosaic supernumerary marker chromosome: delineation of molecular breakpoints and clinical phenotype, and comparison to other proximal 17p segmental duplications. Yatsenko, S.A., Treadwell-Deering, D., Krull, K., Lewis, R.A., Glaze, D., Stankiewicz, P., Lupski, J.R., Potocki, L. Am. J. Med. Genet. A (2005)
- C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells. Duprez, E., Wagner, K., Koch, H., Tenen, D.G. EMBO J. (2003)
- Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia. Toulouse, A., Rochefort, D., Roussel, J., Joober, R., Rouleau, G.A. Genomics (2003)
- Quantitative real-time RT-PCR analysis of PML-RAR alpha mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129. Gallagher, R.E., Yeap, B.Y., Bi, W., Livak, K.J., Beaubier, N., Rao, S., Bloomfield, C.D., Appelbaum, F.R., Tallman, M.S., Slack, J.L., Willman, C.L. Blood (2003)
- Glycolipid antigens of human polymorphonuclear neutrophils and the inducible HL-60 myeloid leukemia line. Symington, F.W., Hedges, D.L., Hakomori, S. J. Immunol. (1985)
- Effect of somatostatin analogue (SMS 201-995, Sandostatin) on pancreatic secretion in humans. Creutzfeldt, W., Lembcke, B., Fölsch, U.R., Schleser, S., Koop, I. Am. J. Med. (1987)
- Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice. Dong, J., Liu, J., Lou, B., Li, Z., Ye, X., Wu, M., Jiang, X.C. J. Lipid Res. (2006)