Gene Review:
Grp - gastrin releasing peptide
Mus musculus
Synonyms:
BLP, GRP, Gastrin-releasing peptide
- Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. Ashour, K., Shan, L., Lee, J.H., Schlicher, W., Wada, K., Wada, E., Sunday, M.E. Am. J. Respir. Crit. Care Med. (2006)
- Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists. Chatzistamou, I., Schally, A.V., Sun, B., Armatis, P., Szepeshazi, K. Br. J. Cancer (2000)
- Generation and characterization of mice lacking gastrin-releasing peptide receptor. Wada, E., Watase, K., Yamada, K., Ogura, H., Yamano, M., Inomata, Y., Eguchi, J., Yamamoto, K., Sunday, M.E., Maeno, H., Mikoshiba, K., Ohki-Hamazaki, H., Wada, K. Biochem. Biophys. Res. Commun. (1997)
- Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095. Szepeshazi, K., Schally, A.V., Halmos, G., Groot, K., Radulovic, S. J. Natl. Cancer Inst. (1992)
- The bombesin/gastrin releasing peptide receptor antagonist RC-3095 blocks apomorphine but not MK-801-induced stereotypy in mice. Meller, C.A., Henriques, J.A., Schwartsmann, G., Roesler, R. Peptides (2004)
- Posttraining administration of gastrin-releasing peptide improves memory loss in scopolamine- and hypoxia-induced amnesic mice. Santo-Yamada, Y., Yamada, K., Wada, K. Physiol. Behav. (2001)
- Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Shumyatsky, G.P., Tsvetkov, E., Malleret, G., Vronskaya, S., Hatton, M., Hampton, L., Battey, J.F., Dulac, C., Kandel, E.R., Bolshakov, V.Y. Cell (2002)
- Two distinct receptor subtypes for mammalian bombesin-like peptides. Battey, J., Wada, E. Trends Neurosci. (1991)
- Preclinical evaluation of an anti-autocrine growth factor monoclonal antibody for treatment of patients with small-cell lung cancer. Avis, I.L., Kovacs, T.O., Kasprzyk, P.G., Treston, A.M., Bartholomew, R., Walsh, J.H., Cuttitta, F., Mulshine, J.L. J. Natl. Cancer Inst. (1991)
- Peptide-containing nerve fibers in the stomach wall of rat and mouse. Ekblad, E., Ekelund, M., Graffner, H., Håkanson, R., Sundler, F. Gastroenterology (1985)
- Evidence for autocrine actions of neuromedin B and gastrin-releasing peptide in non-small cell lung cancer. Siegfried, J.M., Krishnamachary, N., Gaither Davis, A., Gubish, C., Hunt, J.D., Shriver, S.P. Pulmonary pharmacology & therapeutics. (1999)
- Inhibition of growth of HT-29 human colon cancer xenografts in nude mice by treatment with bombesin/gastrin releasing peptide antagonist (RC-3095). Radulovic, S., Miller, G., Schally, A.V. Cancer Res. (1991)
- Antagonists of bombesin/gastrin-releasing peptide inhibit growth of SW-1990 human pancreatic adenocarcinoma and production of cyclic AMP. Qin, Y., Ertl, T., Cai, R.Z., Horvàth, J.E., Groot, K., Schally, A.V. Int. J. Cancer (1995)
- Effective treatment of experimental U-87MG human glioblastoma in nude mice with a targeted cytotoxic bombesin analogue, AN-215. Szereday, Z., Schally, A.V., Nagy, A., Plonowski, A., Bajo, A.M., Halmos, G., Szepeshazi, K., Groot, K. Br. J. Cancer (2002)
- Effect of OKY-046 and ONO-3708 on liver injury in mice. Nagai, H., Aoki, M., Shimazawa, T., Yakuo, I., Koda, A., Kasahara, M. Jpn. J. Pharmacol. (1989)
- Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. King, K.A., Torday, J.S., Sunday, M.E. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung. Shan, L., Emanuel, R.L., Dewald, D., Torday, J.S., Asokanathan, N., Wada, K., Wada, E., Sunday, M.E. Am. J. Physiol. Lung Cell Mol. Physiol. (2004)
- Identification of key amino acids in the gastrin-releasing peptide receptor (GRPR) responsible for high affinity binding of gastrin-releasing peptide (GRP). Nakagawa, T., Hocart, S.J., Schumann, M., Tapia, J.A., Mantey, S.A., Coy, D.H., Tokita, K., Katsuno, T., Jensen, R.T. Biochem. Pharmacol. (2005)
- Gastrointestinal peptide signalling in health and disease. Rozengurt, E., Guha, S., Sinnett-Smith, J. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement. (2002)
- Arachidonic acid release by bombesin. A novel postreceptor target for heterologous mitogenic desensitization. Millar, J.B., Rozengurt, E. J. Biol. Chem. (1990)
- Purification and characterization of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells. Feldman, R.I., Wu, J.M., Jenson, J.C., Mann, E. J. Biol. Chem. (1990)
- Bombesin receptor in membranes from Swiss 3T3 cells. Binding characteristics, affinity labelling and modulation by guanine nucleotides. Sinnett-Smith, J., Lehmann, W., Rozengurt, E. Biochem. J. (1990)
- Activation of neuromedin B-preferring bombesin receptors on rat glioblastoma C-6 cells increases cellular Ca2+ and phosphoinositides. Wang, L.H., Battey, J.F., Wada, E., Lin, J.T., Mantey, S., Coy, D.H., Jensen, R.T. Biochem. J. (1992)
- Minimal ligand analysis of gastrin releasing peptide. Receptor binding and mitogenesis. Heimbrook, D.C., Boyer, M.E., Garsky, V.M., Balishin, N.L., Kiefer, D.M., Oliff, A., Riemen, M.W. J. Biol. Chem. (1988)
- Identification of the bombesin receptor on murine and human cells by cross-linking experiments. Kris, R.M., Hazan, R., Villines, J., Moody, T.W., Schlessinger, J. J. Biol. Chem. (1987)
- Islet function phenotype in gastrin-releasing peptide receptor gene-deficient mice. Persson, K., Pacini, G., Sundler, F., Ahrén, B. Endocrinology (2002)
- Comparison of the peptide structural requirements for high affinity interaction with bombesin receptors. Lin, J.T., Coy, D.H., Mantey, S.A., Jensen, R.T. Eur. J. Pharmacol. (1995)
- G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly. Buhl, A.M., Johnson, N.L., Dhanasekaran, N., Johnson, G.L. J. Biol. Chem. (1995)
- Gastrin-releasing peptide promotes suprachiasmatic nuclei cellular rhythmicity in the absence of vasoactive intestinal polypeptide-VPAC2 receptor signaling. Brown, T.M., Hughes, A.T., Piggins, H.D. J. Neurosci. (2005)
- Gastrin releasing peptide (GRP): effects on basal and stimulated insulin and glucagon secretion in the mouse. Pettersson, M., Ahrén, B. Peptides (1987)
- Protein kinase C-dependent activation of a myelin basic protein kinase by gastrin-releasing peptide in Swiss 3T3 fibroblasts. Hansson, A. Cell. Signal. (1991)
- Distinguishing bombesin receptor subtypes using the oocyte assay. Shapira, H., Wada, E., Battey, J.F., Jensen, R.T., Coy, D.H., Kusano, K. Biochem. Biophys. Res. Commun. (1991)
- Molecular basis of the selectivity of gastrin-releasing peptide receptor for gastrin-releasing peptide. Tokita, K., Hocart, S.J., Coy, D.H., Jensen, R.T. Mol. Pharmacol. (2002)
- Gastrin-releasing peptide mediates photic entrainable signals to dorsal subsets of suprachiasmatic nucleus via induction of Period gene in mice. Aida, R., Moriya, T., Araki, M., Akiyama, M., Wada, K., Wada, E., Shibata, S. Mol. Pharmacol. (2002)
- Peptide receptor antagonists in the study of insulin and glucagon secretion in mice. Karlsson, S., Ahrén, B. Eur. J. Pharmacol. (1990)
- Diurnal regulation of the gastrin-releasing peptide receptor in the mouse circadian clock. Karatsoreos, I.N., Romeo, R.D., McEwen, B.S., Silver, R. Eur. J. Neurosci. (2006)
- Tyrosine 220 in the 5th transmembrane domain of the neuromedin B receptor is critical for the high selectivity of the peptoid antagonist PD168368. Tokita, K., Hocart, S.J., Katsuno, T., Mantey, S.A., Coy, D.H., Jensen, R.T. J. Biol. Chem. (2001)
- Effective inhibition of experimental human ovarian cancers with a targeted cytotoxic bombesin analogue AN-215. Engel, J.B., Keller, G., Schally, A.V., Halmos, G., Hammann, B., Nagy, A. Clin. Cancer Res. (2005)