Gene Review:
CR2 - complement component (3d/Epstein Barr...
Homo sapiens
Synonyms:
C3DR, CD21, CR, CVID7, Complement C3d receptor, ...
- Epstein Barr virus/complement C3d receptor is an interferon alpha receptor. Delcayre, A.X., Salas, F., Mathur, S., Kovats, K., Lotz, M., Lernhardt, W. EMBO J. (1991)
- Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement. Weis, J.J., Fearon, D.T., Klickstein, L.B., Wong, W.W., Richards, S.A., de Bruyn Kops, A., Smith, J.A., Weis, J.H. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Identification of an additional class of C3-binding membrane proteins of human peripheral blood leukocytes and cell lines. Cole, J.L., Housley, G.A., Dykman, T.R., MacDermott, R.P., Atkinson, J.P. Proc. Natl. Acad. Sci. U.S.A. (1985)
- In vivo decrease in the expression of complement receptor 2 on B-cells in HIV infection. Scott, M.E., Landay, A.L., Lint, T.F., Spear, G.T. AIDS (1993)
- Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Fearon, D.T., Carroll, M.C. Annu. Rev. Immunol. (2000)
- CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system. Levy, S., Todd, S.C., Maecker, H.T. Annu. Rev. Immunol. (1998)
- The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Fearon, D.T., Carter, R.H. Annu. Rev. Immunol. (1995)
- Association of Epstein-Barr virus with leiomyosarcomas in children with AIDS. McClain, K.L., Leach, C.T., Jenson, H.B., Joshi, V.V., Pollock, B.H., Parmley, R.T., DiCarlo, F.J., Chadwick, E.G., Murphy, S.B. N. Engl. J. Med. (1995)
- Activation of Epstein-Barr virus/C3d receptor (gp140, CR2, CD21) on human B lymphoma cell surface triggers Cbl tyrosine phosphorylation, its association with p85 subunit, Crk-L and Syk and its dissociation with Vav. Lottin-Divoux, S., Jean, D., Le Romancer, M., Frade, R. Cell. Signal. (2006)
- Interaction of iC3b with recombinant isotypic and chimeric forms of CR2. Kalli, K.R., Ahearn, J.M., Fearon, D.T. J. Immunol. (1991)
- Activation of CD21 and CD23 gene expression by Kaposi's sarcoma-associated herpesvirus RTA. Chang, H., Gwack, Y., Kingston, D., Souvlis, J., Liang, X., Means, R.E., Cesarman, E., Hutt-Fletcher, L., Jung, J.U. J. Virol. (2005)
- CD21-Dependent infection of an epithelial cell line, 293, by Epstein-Barr virus. Fingeroth, J.D., Diamond, M.E., Sage, D.R., Hayman, J., Yates, J.L. J. Virol. (1999)
- Bone marrow transplantation depleted of T cells followed by repletion with incremental doses of donor lymphocytes for relapsing patients with chronic myeloid leukemia: a therapeutic strategy. Novitzky, N., Rubinstein, R., Hallett, J.M., du Toit, C.E., Thomas, V.L. Transplantation (2000)
- Expression, molecular association, and functions of C3 complement receptors CR1 (CD35) and CR2 (CD21) on the human T cell line HPB-ALL. Delibrias, C.C., Fischer, E., Bismuth, G., Kazatchkine, M.D. J. Immunol. (1992)
- Signaling through the EBV/C3d receptor (CR2, CD21) in human B lymphocytes: activation of phosphatidylinositol 3-kinase via a CD19-independent pathway. Bouillie, S., Barel, M., Frade, R. J. Immunol. (1999)
- Comparative structure and evolution of murine CR2. The homolog of the human C3d/EBV receptor (CD21). Fingeroth, J.D. J. Immunol. (1990)
- The sequential appearance of Ia-like antigens and two different complement receptors during the maturation of human neutrophils. Ross, G.D., Jarowski, C.I., Rabellino, E.M., Winchester, R.J. J. Exp. Med. (1978)
- Identification and characterization of complement C3 receptors on human astrocytes. Gasque, P., Chan, P., Mauger, C., Schouft, M.T., Singhrao, S., Dierich, M.P., Morgan, B.P., Fontaine, M. J. Immunol. (1996)
- CR1(CD35) and CR2(CD21) complement C3 receptors are expressed on normal human thymocytes and mediate infection of thymocytes with opsonized human immunodeficiency virus. Delibrias, C.C., Mouhoub, A., Fischer, E., Kazatchkine, M.D. Eur. J. Immunol. (1994)
- B cell activation leads to shedding of complement receptor type II (CR2/CD21). Masilamani, M., Kassahn, D., Mikkat, S., Glocker, M.O., Illges, H. Eur. J. Immunol. (2003)
- Redox control of EBV infection: prevention by thiol-dependent modulation of functional CD21/EBV receptor expression. Nishinaka, Y., Nakamura, H., Okada, N., Okada, H., Yodoi, J. Antioxid. Redox Signal. (2001)
- Infection of human thymocytes by Epstein-Barr virus. Watry, D., Hedrick, J.A., Siervo, S., Rhodes, G., Lamberti, J.J., Lambris, J.D., Tsoukas, C.D. J. Exp. Med. (1991)
- Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19. Matsumoto, A.K., Kopicky-Burd, J., Carter, R.H., Tuveson, D.A., Tedder, T.F., Fearon, D.T. J. Exp. Med. (1991)
- Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes. Matsumoto, A.K., Martin, D.R., Carter, R.H., Klickstein, L.B., Ahearn, J.M., Fearon, D.T. J. Exp. Med. (1993)
- The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules. Bradbury, L.E., Kansas, G.S., Levy, S., Evans, R.L., Tedder, T.F. J. Immunol. (1992)
- Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes. Leslie, R.G., Prodinger, W.M., Nielsen, C.H. Eur. J. Immunol. (2003)
- Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein. Barel, M., Balbo, M., Gauffre, A., Frade, R. Mol. Immunol. (1995)
- Gamma-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes. Nichols, T.C., Guthridge, J.M., Karp, D.R., Molina, H., Fletcher, D.R., Holers, V.M. Eur. J. Immunol. (1998)
- Activation of the EBV/C3d receptor (CR2, CD21) on human B lymphocyte surface triggers tyrosine phosphorylation of the 95-kDa nucleolin and its interaction with phosphatidylinositol 3 kinase. Barel, M., Le Romancer, M., Frade, R. J. Immunol. (2001)
- Surface markers on human B and T-lymphocytes. IX. Two-color immunofluorescence studies on the association between ebv receptors and complement receptors on the surface of lymphoid cell lines. Yefenof, E., Klein, G., Jondal, M., Oldstone, M.B. Int. J. Cancer (1976)
- Decreased levels of serum soluble complement receptor-II (CR2/CD21) in patients with rheumatoid arthritis. Masilamani, M., von Kempis, J., Illges, H. Rheumatology (Oxford, England) (2004)
- Expression and localization of proteins of the complement system in human skin. Dovezenski, N., Billetta, R., Gigli, I. J. Clin. Invest. (1992)
- Expression of human complement receptor type 2 (CD21) in mice during early B cell development results in a reduction in mature B cells and hypogammaglobulinemia. Marchbank, K.J., Kulik, L., Gipson, M.G., Morgan, B.P., Holers, V.M. J. Immunol. (2002)
- Transmembrane signals generated through MHC class II, CD19, CD20, CD39, and CD40 antigens induce LFA-1-dependent and independent adhesion in human B cells through a tyrosine kinase-dependent pathway. Kansas, G.S., Tedder, T.F. J. Immunol. (1991)
- Ligation of the functional domain of complement receptor type 2 (CR2, CD21) is relevant for complex formation in T cell lines. Prodinger, W.M., Larcher, C., Schwendinger, M., Dierich, M.P. J. Immunol. (1996)
- Solution structure of the complex between CR2 SCR 1-2 and C3d of human complement: an X-ray scattering and sedimentation modelling study. Gilbert, H.E., Eaton, J.T., Hannan, J.P., Holers, V.M., Perkins, S.J. J. Mol. Biol. (2005)