Gene Review:
Enpep - glutamyl aminopeptidase
Mus musculus
Synonyms:
6030431M22Rik, AP-A, APA, Aminopeptidase A, BP-1/6C3 antigen, ...
- Hypertension and angiotensin II hypersensitivity in aminopeptidase A-deficient mice. Mitsui, T., Nomura, S., Okada, M., Ohno, Y., Kobayashi, H., Nakashima, Y., Murata, Y., Takeuchi, M., Kuno, N., Nagasaka, T., O-Wang, J., Cooper, M.D., Mizutani, S. Mol. Med. (2003)
- Enhancement of myoblast microencapsulation for gene therapy. Li, A.A., Shen, F., Zhang, T., Cirone, P., Potter, M., Chang, P.L. Journal of biomedical materials research. Part B, Applied biomaterials. (2006)
- A nephritogenic rat monoclonal antibody to mouse aminopeptidase A. Induction of massive albuminuria after a single intravenous injection. Assmann, K.J., van Son, J.P., Dijkman, H.B., Koene, R.A. J. Exp. Med. (1992)
- Physiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells. Setiady, Y.Y., Ohno, K., Samy, E.T., Bagavant, H., Qiao, H., Sharp, C., She, J.X., Tung, K.S. Blood (2006)
- Mouse glomerular epithelial cells in culture with features of podocytes in vivo express aminopeptidase A and angiotensinogen but not other components of the renin-angiotensin system. Mentzel, S., Van Son, J.P., De Jong, A.S., Dijkman, H.B., Koene, R.A., Wetzels, J.F., Assmann, K.J. J. Am. Soc. Nephrol. (1997)
- Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice. Faber, F., Gembardt, F., Sun, X., Mizutani, S., Siems, W.E., Walther, T. Regul. Pept. (2006)
- Brain renin-angiotensin system blockade by systemically active aminopeptidase A inhibitors: a potential treatment of salt-dependent hypertension. Fournie-Zaluski, M.C., Fassot, C., Valentin, B., Djordjijevic, D., Reaux-Le Goazigo, A., Corvol, P., Roques, B.P., Llorens-Cortes, C. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release. Zini, S., Fournie-Zaluski, M.C., Chauvel, E., Roques, B.P., Corvol, P., Llorens-Cortes, C. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Albuminuria in mice after injection of antibodies against aminopeptidase A: role of angiotensin II. Gerlofs-Nijland, M.E., Assmann, K.J., Dijkman, H.B., Dieker, J.W., van Son, J.P., Mentzel, S., van Kats, J.P., Danser, A.H., Smithies, O., Groenen, P.J., Wetzels, J.F. J. Am. Soc. Nephrol. (2001)
- Role of ATP and Pi in the mechanism of insulin secretion in the mouse insulinoma betaTC3 cell line. Papas, K.K., Long, R.C., Constantinidis, I., Sambanis, A. Biochem. J. (1997)
- Inhibition of aminopeptidase A activity causes an acute albuminuria in mice: an angiotensin II-mediated effect? Mentzel, S., Assmann, K.J., Dijkman, H.B., de Jong, A.S., van Son, J.P., Wetzels, J.F., Koene, R.A. Nephrol. Dial. Transplant. (1996)
- Effects of alginate composition on the metabolic, secretory, and growth characteristics of entrapped beta TC3 mouse insulinoma cells. Constantinidis, I., Rask, I., Long, R.C., Sambanis, A. Biomaterials (1999)
- Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes. Aoyagi, T., Tobe, H., Kojima, F., Hamada, M., Takeuchi, T., Umezawa, H. J. Antibiot. (1978)
- Aminopeptidase A, which generates one of the main effector peptides of the brain renin-angiotensin system, angiotensin III, has a key role in central control of arterial blood pressure. Reaux, A., Iturrioz, X., Vazeux, G., Fournie-Zaluski, M.C., David, C., Roques, B.P., Corvol, P., Llorens-Cortes, C. Biochem. Soc. Trans. (2000)
- A tyrosine residue essential for catalytic activity in aminopeptidase A. Vazeux, G., Iturrioz, X., Corvol, P., Llorens-Cortès, C. Biochem. J. (1997)
- Molecular cloning and expression of aminopeptidase A isoforms from rat hippocampus. Lee, H.J., Tomioka, M., Takaki, Y., Masumoto, H., Saido, T.C. Biochim. Biophys. Acta (2000)
- Aminopeptidase A activity of the murine B-lymphocyte differentiation antigen BP-1/6C3. Wu, Q., Li, L., Cooper, M.D., Pierres, M., Gorvel, J.P. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Histochemical study of aminopeptidase M, aminopeptidase A, and gamma-glutamyltransferase in the nasal cavity of laboratory rodents andman. Kubisová, I., Pospísilová, B. Sborník vědeckých prací Lékařské fakulty Karlovy university v Hradci Králové. (1994)
- Contribution of molecular modeling and site-directed mutagenesis to the identification of a new residue, glutamate 215, involved in the exopeptidase specificity of aminopeptidase A. Rozenfeld, R., Iturrioz, X., Okada, M., Maigret, B., Llorens-Cortes, C. Biochemistry (2003)
- Pituitary aminopeptidase activities involved in blood-pressure regulation are modified by dietary cholesterol: sex differences. Ramírez-Expósito, M.J., Mayas, M.D., García, M.J., Ramírez, M., Martínez-Martos, J.M. Regul. Pept. (2001)
- T and B cell development in BP-1/6C3/aminopeptidase A-deficient mice. Lin, Q., Taniuchi, I., Kitamura, D., Wang, J., Kearney, J.F., Watanabe, T., Cooper, M.D. J. Immunol. (1998)
- An aminopeptidase from mouse brain cytosol that cleaves N-terminal acidic amino acid residues. Kelly, J.A., Neidle, E.L., Neidle, A. J. Neurochem. (1983)
- Enzyme cytochemistry combined with electron microscopy, pharmacokinetics, and clinical chemistry for the evaluation of the effects of steady-state valproic acid concentrations on the mouse. Graf, R., Gossrau, R., Merker, H.J., Schwabe, R., Stahlmann, R., Nau, H. Histochemistry (1985)
- Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Parkin, E.T., Turner, A.J., Hooper, N.M. Biochem. J. (1999)
- Organ distribution of aminopeptidase A and dipeptidyl peptidase IV in normal mice. Mentzel, S., Dijkman, H.B., Van Son, J.P., Koene, R.A., Assmann, K.J. J. Histochem. Cytochem. (1996)
- The C-terminal domain of aminopeptidase A is an intramolecular chaperone required for the correct folding, cell surface expression, and activity of this monozinc aminopeptidase. Rozenfeld, R., Muller, L., Messari, S.E., Llorens-Cortes, C. J. Biol. Chem. (2004)
- Glucose metabolism in vitro of cultured and transplanted mouse pancreatic islets microencapsulated by means of a high-voltage electrostatic field. King, A., Sandler, S., Andersson, A., Hellerström, C., Kulseng, B., Skjåk-Braek, G. Diabetes Care (1999)