Gene Review:
Kcnma1 - potassium large conductance calcium...
Mus musculus
Synonyms:
5730414M22Rik, BK channel, BK channel alpha subunit, BKCA alpha, BKCa, ...
- A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel alpha-subunits. McCartney, C.E., McClafferty, H., Huibant, J.M., Rowan, E.G., Shipston, M.J., Rowe, I.C. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Overactive bladder and incontinence in the absence of the BK large conductance Ca2+-activated K+ channel. Meredith, A.L., Thorneloe, K.S., Werner, M.E., Nelson, M.T., Aldrich, R.W. J. Biol. Chem. (2004)
- Cochlear Function in Mice Lacking the BK Channel {alpha}, beta1, or beta4 Subunits. Pyott, S.J., Meredith, A.L., Fodor, A.A., Vázquez, A.E., Yamoah, E.N., Aldrich, R.W. J. Biol. Chem. (2007)
- Modulation of big K+ channel activity by ryanodine receptors and L-type Ca2+ channels in neurons. Chavis, P., Ango, F., Michel, J.M., Bockaert, J., Fagni, L. Eur. J. Neurosci. (1998)
- Cardioprotective effects of estradiol include the activation of large-conductance Ca(2+)-activated K(+) channels in cardiac mitochondria. Ohya, S., Kuwata, Y., Sakamoto, K., Muraki, K., Imaizumi, Y. Am. J. Physiol. Heart Circ. Physiol. (2005)
- Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel. Werner, M.E., Zvara, P., Meredith, A.L., Aldrich, R.W., Nelson, M.T. J. Physiol. (Lond.) (2005)
- Vasoregulation by the beta1 subunit of the calcium-activated potassium channel. Brenner, R., Peréz, G.J., Bonev, A.D., Eckman, D.M., Kosek, J.C., Wiler, S.W., Patterson, A.J., Nelson, M.T., Aldrich, R.W. Nature (2000)
- mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Butler, A., Tsunoda, S., McCobb, D.P., Wei, A., Salkoff, L. Science (1993)
- BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Brenner, R., Chen, Q.H., Vilaythong, A., Toney, G.M., Noebels, J.L., Aldrich, R.W. Nat. Neurosci. (2005)
- Activation of calcium-dependent potassium channels in mouse [correction of rat] brain neurons by neurotrophin-3 and nerve growth factor. Holm, N.R., Christophersen, P., Olesen, S.P., Gammeltoft, S. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Activation of NFATc3 Down-regulates the beta1 Subunit of Large Conductance, Calcium-activated K+ Channels in Arterial Smooth Muscle and Contributes to Hypertension. Nieves-Cintrón, M., Amberg, G.C., Nichols, C.B., Molkentin, J.D., Santana, L.F. J. Biol. Chem. (2007)
- Diversity of Ca(2+)-activated K(+) channel transcripts in inner ear hair cells. Beisel, K.W., Rocha-Sanchez, S.M., Ziegenbein, S.J., Morris, K.A., Kai, C., Kawai, J., Carninci, P., Hayashizaki, Y., Davis, R.L. Gene (2007)
- Functionally diverse complement of large conductance calcium- and voltage-activated potassium channel (BK) alpha-subunits generated from a single site of splicing. Chen, L., Tian, L., MacDonald, S.H., McClafferty, H., Hammond, M.S., Huibant, J.M., Ruth, P., Knaus, H.G., Shipston, M.J. J. Biol. Chem. (2005)
- Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes. Schreiber, M., Wei, A., Yuan, A., Gaut, J., Saito, M., Salkoff, L. J. Biol. Chem. (1998)
- Leucine zipper domain targets cAMP-dependent protein kinase to mammalian BK channels. Tian, L., Coghill, L.S., MacDonald, S.H., Armstrong, D.L., Shipston, M.J. J. Biol. Chem. (2003)
- Molecular identification and physiological roles of parotid acinar cell maxi-k channels. Romanenko, V., Nakamoto, T., Srivastava, A., Melvin, J.E., Begenisich, T. J. Biol. Chem. (2006)
- Localization and developmental expression of BK channels in mammalian cochlear hair cells. Hafidi, A., Beurg, M., Dulon, D. Neuroscience (2005)
- 17beta-Estradiol upregulates distinct maxi-K channel transcripts in mouse uterus. Holdiman, A.J., Fergus, D.J., England, S.K. Mol. Cell. Endocrinol. (2002)
- Distal Colonic K+ Secretion Occurs via BK Channels. Sausbier, M., Matos, J.E., Sausbier, U., Beranek, G., Arntz, C., Neuhuber, W., Ruth, P., Leipziger, J. J. Am. Soc. Nephrol. (2006)
- Slo3 K+ Channels: Voltage and pH Dependence of Macroscopic Currents. Zhang, X., Zeng, X., Lingle, C.J. J. Gen. Physiol. (2006)
- Myometrial maxi-K channel beta1 subunit modulation during pregnancy and after 17beta-estradiol stimulation. Benkusky, N.A., Korovkina, V.P., Brainard, A.M., England, S.K. FEBS Lett. (2002)
- Membrane-delimited inhibition of maxi-K channel activity by the intermediate conductance Ca2+-activated K channel. Thompson, J., Begenisich, T. J. Gen. Physiol. (2006)
- Glucocorticoids block protein kinase A inhibition of calcium-activated potassium channels. Shipston, M.J., Kelly, J.S., Antoni, F.A. J. Biol. Chem. (1996)
- Ca(2+)-activated K(+) channels of the BK-type in the mouse brain. Sausbier, U., Sausbier, M., Sailer, C.A., Arntz, C., Knaus, H.G., Neuhuber, W., Ruth, P. Histochem. Cell Biol. (2006)
- Molecular identification of Ca2+-activated K+ channels in parotid acinar cells. Nehrke, K., Quinn, C.C., Begenisich, T. Am. J. Physiol., Cell Physiol. (2003)
- BK channel beta1-subunit regulation of calcium handling and constriction in tracheal smooth muscle. Semenov, I., Wang, B., Herlihy, J.T., Brenner, R. Am. J. Physiol. Lung Cell Mol. Physiol. (2006)
- State-dependent modulation of mSlo, a cloned calcium-dependent potassium channel. Müller, M., Madan, D., Levitan, I.B. Neuropharmacology (1996)
- Extrasynaptic localization of inactivating calcium-activated potassium channels in mouse inner hair cells. Pyott, S.J., Glowatzki, E., Trimmer, J.S., Aldrich, R.W. J. Neurosci. (2004)