Gene Review:
DRD3 - dopamine receptor D3
Homo sapiens
Synonyms:
D(3) dopamine receptor, D3DR, Dopamine D3 receptor, ETM1, FET1
Sweet,
Nimgaonkar,
Kamboh,
Lopez,
Zhang,
DeKosky,
Paclt,
Koudelová,
Krepelová,
Uhlíková,
Gazdíková,
Bauer,
Soma,
Nakayama,
Rahmutula,
Uwabo,
Sato,
Kunimoto,
Aoi,
Kosuge,
Kanmatsuse,
Massat,
Souery,
Del-Favero,
Van Gestel,
Serretti,
Macciardi,
Smeraldi,
Kaneva,
Adolfsson,
Nylander,
Blackwood,
Muir,
Papadimitriou,
Dikeos,
Oruc,
Segman,
Ivezic,
Aschauer,
Ackenheil,
Fuchshuber,
Dam,
Jakovljevic,
Peltonen,
Hilger,
Hentges,
Staner,
Milanova,
Jazin,
Lerer,
Van Broeckhoven,
Mendlewicz,
Le Foll,
Goldberg,
Sokoloff,
Czermak,
Lehofer,
Renger,
Wagner,
Lemonis,
Rohrhofer,
Schauenstein,
Liebmann,
Vogel,
Pfeifer,
Schaub,
Grabe,
Barnow,
Freyberger,
Cascorbi,
Siu,
Tyndale,
Craig,
Hart,
Carson,
McIlroy,
Passmore,
Benedetti,
Serretti,
Colombo,
Lilli,
Lorenzi,
Smeraldi,
Krebs,
Guillin,
Bourdell,
Schwartz,
Olie,
Poirier,
Sokoloff,
Le Foll,
Goldberg,
Sokoloff,
Kaiser,
Hofer,
Grapengiesser,
Gasser,
Kupsch,
Roots,
Brockmöller,
- Association analysis of the dopamine D3 receptor gene ser9gly and brain-derived neurotrophic factor gene val66met polymorphisms with antipsychotic-induced persistent tardive dyskinesia and clinical expression in Chinese schizophrenic patients. Liou, Y.J., Liao, D.L., Chen, J.Y., Wang, Y.C., Lin, C.C., Bai, Y.M., Yu, S.C., Lin, M.W., Lai, I.C. Neuromolecular Med. (2004)
- Association between dopamine receptor genes and migraine without aura in a Sardinian sample. Del Zompo, M., Cherchi, A., Palmas, M.A., Ponti, M., Bocchetta, A., Gessa, G.L., Piccardi, M.P. Neurology (1998)
- Ser9Gly polymorphism in the dopamine D3 receptor gene is not associated with essential hypertension in the Japanese. Soma, M., Nakayama, K., Rahmutula, D., Uwabo, J., Sato, M., Kunimoto, M., Aoi, N., Kosuge, K., Kanmatsuse, K. Med. Sci. Monit. (2002)
- A functional variant of the dopamine D3 receptor is associated with risk and age-at-onset of essential tremor. Jeanneteau, F., Funalot, B., Jankovic, J., Deng, H., Lagarde, J.P., Lucotte, G., Sokoloff, P. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Linkage with the Ser9Gly DRD3 polymorphism in essential tremor families. Lucotte, G., Lagarde, J.P., Funalot, B., Sokoloff, P. Clin. Genet. (2006)
- Genetic variation analysis in parkinson disease patients with and without hallucinations: case-control study. Goetz, C.G., Burke, P.F., Leurgans, S., Berry-Kravis, E., Blasucci, L.M., Raman, R., Zhou, L. Arch. Neurol. (2001)
- Dopamine receptor D2 and D3 gene variants are not associated with the antidepressant effect of total sleep deprivation in bipolar depression. Benedetti, F., Serretti, A., Colombo, C., Lilli, R., Lorenzi, C., Smeraldi, E. Psychiatry research. (2003)
- Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia. Anney, R.J., Rees, M.I., Bryan, E., Spurlock, G., Williams, N., Norton, N., Williams, H., Cardno, A., Zammit, S., Jones, S., Jones, G., Hoogendoorn, B., Smith, K., Hamshere, M.L., Coleman, S., Guy, C., O'Donovan, M.C., Owen, M.J., Buckland, P.R. Mol. Psychiatry (2002)
- DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder. Nicolini, H., Cruz, C., Camarena, B., Orozco, B., Kennedy, J.L., King, N., Weissbecker, K., de la Fuente, J.R., Sidenberg, D. Mol. Psychiatry (1996)
- Psychotic symptoms in Alzheimer's disease are not influenced by polymorphic variation at the dopamine receptor DRD3 gene. Craig, D., Hart, D.J., Carson, R., McIlroy, S.P., Passmore, A.P. Neurosci. Lett. (2004)
- Non-nicotinic therapies for smoking cessation. Siu, E.C., Tyndale, R.F. Annu. Rev. Pharmacol. Toxicol. (2007)
- Pharmacogenomics in schizophrenia: the quest for individualized therapy. Basile, V.S., Masellis, M., Potkin, S.G., Kennedy, J.L. Hum. Mol. Genet. (2002)
- Dopamine selectively induces migration and homing of naive CD8+ T cells via dopamine receptor D3. Watanabe, Y., Nakayama, T., Nagakubo, D., Hieshima, K., Jin, Z., Katou, F., Hashimoto, K., Yoshie, O. J. Immunol. (2006)
- Interaction between polymorphisms of the dopamine D3 receptor and manganese superoxide dismutase genes in susceptibility to tardive dyskinesia. Zhang, Z.J., Zhang, X.B., Hou, G., Yao, H., Reynolds, G.P. Psychiatr. Genet. (2003)
- Association study between dopamine D3 receptor gene variant and personality traits. Jönsson, E.G., Burgert, E., Crocq, M.A., Gustavsson, J.P., Forslund, K., Mattila-Evenden, M., Rylander, G., Flyckt, L.K., Bjerkenstedt, L., Wiesel, F.A., Asberg, M., Bergman, H. Am. J. Med. Genet. B Neuropsychiatr. Genet. (2003)
- Association of the MscI polymorphism of the dopamine D3 receptor gene with tardive dyskinesia in schizophrenia. Basile, V.S., Masellis, M., Badri, F., Paterson, A.D., Meltzer, H.Y., Lieberman, J.A., Potkin, S.G., Macciardi, F., Kennedy, J.L. Neuropsychopharmacology (1999)
- Dopamine D3 receptor ligands for the treatment of tobacco dependence. Le Foll, B., Goldberg, S.R., Sokoloff, P. Expert opinion on investigational drugs (2007)
- Dopamine-related genes and their relationships to monoamine metabolites in CSF. Jönsson, E., Sedvall, G., Brené, S., Gustavsson, J.P., Geijer, T., Terenius, L., Crocq, M.A., Lannfelt, L., Tylec, A., Sokoloff, P., Schwartz, J.C., Wiesel, F.A. Biol. Psychiatry (1996)
- Dopamine receptor genetic variation, psychosis, and aggression in Alzheimer disease. Sweet, R.A., Nimgaonkar, V.L., Kamboh, M.I., Lopez, O.L., Zhang, F., DeKosky, S.T. Arch. Neurol. (1998)
- Dopamine receptor D3 mRNA expression in human lymphocytes is negatively correlated with the personality trait of persistence. Czermak, C., Lehofer, M., Renger, H., Wagner, E.M., Lemonis, L., Rohrhofer, A., Schauenstein, K., Liebmann, P.M. J. Neuroimmunol. (2004)
- No association between polymorphisms in the human dopamine D3 and D4 receptors genes and alcoholism. Parsian, A., Chakraverty, S., Fisher, L., Cloninger, C.R. Am. J. Med. Genet. (1997)
- Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene. Vandenbergh, D.J., Rodriguez, L.A., Hivert, E., Schiller, J.H., Villareal, G., Pugh, E.W., Lachman, H., Uhl, G.R. Am. J. Med. Genet. (2000)
- A transmission disequilibrium test of the Ser9/Gly dopamine D3 receptor gene polymorphism in adult attention-deficit hyperactivity disorder. Muglia, P., Jain, U., Kennedy, J.L. Behav. Brain Res. (2002)
- Decreased levels of dopamine D3 receptor mRNA in schizophrenic and bipolar patients. Vogel, M., Pfeifer, S., Schaub, R.T., Grabe, H.J., Barnow, S., Freyberger, H.J., Cascorbi, I. Neuropsychobiology (2004)
- The dopamine D3 receptor and drug dependence: effects on reward or beyond? Le Foll, B., Goldberg, S.R., Sokoloff, P. Neuropharmacology (2005)
- Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia. Krebs, M.O., Guillin, O., Bourdell, M.C., Schwartz, J.C., Olie, J.P., Poirier, M.F., Sokoloff, P. Mol. Psychiatry (2000)
- Allelic variation in the human prodynorphin gene promoter and schizophrenia. Ventriglia, M., Bocchio Chiavetto, L., Bonvicini, C., Tura, G.B., Bignotti, S., Racagni, G., Gennarelli, M. Neuropsychobiology (2002)
- L -dopa-induced adverse effects in PD and dopamine transporter gene polymorphism. Kaiser, R., Hofer, A., Grapengiesser, A., Gasser, T., Kupsch, A., Roots, I., Brockmöller, J. Neurology (2003)
- Biochemical markers and genetic research of ADHD. Paclt, I., Koudelová, J., Krepelová, A., Uhlíková, P., Gazdíková, M., Bauer, P. Neuro Endocrinol. Lett. (2005)
- Dopamine D3 receptor Ser9Gly polymorphism and risperidone response. Lane, H.Y., Hsu, S.K., Liu, Y.C., Chang, Y.C., Huang, C.H., Chang, W.H. Journal of clinical psychopharmacology. (2005)
- The D4 dopamine receptor (DRD4) maps to distal 11p close to HRAS. Gelernter, J., Kennedy, J.L., van Tol, H.H., Civelli, O., Kidd, K.K. Genomics (1992)
- Dopamine receptor genes and migraine with and without aura: an association study. Shepherd, A.G., Lea, R.A., Hutchins, C., Jordan, K.L., Brimage, P.J., Griffiths, L.R. Headache. (2002)
- Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders. Massat, I., Souery, D., Del-Favero, J., Van Gestel, S., Serretti, A., Macciardi, F., Smeraldi, E., Kaneva, R., Adolfsson, R., Nylander, P.O., Blackwood, D., Muir, W., Papadimitriou, G.N., Dikeos, D., Oruc, L., Segman, R.H., Ivezic, S., Aschauer, H., Ackenheil, M., Fuchshuber, S., Dam, H., Jakovljevic, M., Peltonen, L., Hilger, C., Hentges, F., Staner, L., Milanova, V., Jazin, E., Lerer, B., Van Broeckhoven, C., Mendlewicz, J. Am. J. Med. Genet. (2002)
- Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis. Jönsson, E.G., Flyckt, L., Burgert, E., Crocq, M.A., Forslund, K., Mattila-Evenden, M., Rylander, G., Asberg, M., Nimgaonkar, V.L., Edman, G., Bjerkenstedt, L., Wiesel, F.A., Sedvall, G.C. Psychiatr. Genet. (2003)