The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

DYT6  -  dystonia 6, torsion (autosomal dominant)

Homo sapiens

This record was replaced with 55145.
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of DYT6


Psychiatry related information on DYT6

  • Adult-onset Leukoencephalopathy with vanishing white matter presenting with dementia [6].
  • CONCLUSIONS: Adult onset tic disorders represent an underrecognised condition that is more common than generally appreciated or reported [7].
  • CONCLUSIONS: Adult onset nocturnal enuresis with absent daytime incontinence is a serious symptom that usually heralds significant urethral obstruction, and a high incidence of bladder diverticulum, hydronephrosis and vesicoureteral reflux [8].
  • Male and female alcoholics (n = 321) with ASPD or DSM III subtypes [Conduct Disorder; Adult Onset ASPD] were compared to non-ASPD alcoholics on several etiological features of alcoholism and its clinical presentation immediately prior to treatment [9].

High impact information on DYT6


Chemical compound and disease context of DYT6


Biological context of DYT6


Anatomical context of DYT6


Associations of DYT6 with chemical compounds


Other interactions of DYT6

  • Although linkage analysis was not completely informative, reconstructed haplotypes excluded linkage between the disease and either DYT6 or DYT7 [18].
  • OBJECTIVE: Adult onset type II citrullinemia is an inherited disorder of amino acid metabolism caused by a deficiency of liver specific argininosuccinate synthetase activity [29].
  • CONCLUSIONS: Adult-onset IBAM is not directly related to dysfunctional mutations in the coding region or intron/exon junctions of the SLC10A2 gene [30].
  • Adult onset IGE shares many features with "classical" IGE, including EEG findings and prognosis, and is likely to represent a genetic epilepsy [31].
  • CONCLUSIONS: Adult-onset myopes comprised nearly half of the simple myopic subjects, and their family history of myopia was similar to that of youth-onset myopes [32].

Analytical, diagnostic and therapeutic context of DYT6


  1. Long-term treatment response and fluorodopa positron emission tomographic scanning of parkinsonism in a family with dopa-responsive dystonia. Nygaard, T.G., Takahashi, H., Heiman, G.A., Snow, B.J., Fahn, S., Calne, D.B. Ann. Neurol. (1992) [Pubmed]
  2. Adult onset Niemann-Pick disease type C presenting with psychosis. Josephs, K.A., Van Gerpen, M.W., Van Gerpen, J.A. J. Neurol. Neurosurg. Psychiatr. (2003) [Pubmed]
  3. Relative risk of spread of symptoms among the focal onset primary dystonias. Weiss, E.M., Hershey, T., Karimi, M., Racette, B., Tabbal, S.D., Mink, J.W., Paniello, R.C., Perlmutter, J.S. Mov. Disord. (2006) [Pubmed]
  4. Adult-onset focal dystonias: presentation and treatment options. Esper, G.J., Charles, P.D., Davis, T.L., Robertson, D. Tennessee medicine : journal of the Tennessee Medical Association. (1997) [Pubmed]
  5. Adult-onset re-emergent stuttering as a presentation of Parkinson's disease. Lim, E.C., Wilder-Smith, E., Ong, B.K., Seet, R.C. Ann. Acad. Med. Singap. (2005) [Pubmed]
  6. Adult-onset Leukoencephalopathy with vanishing white matter presenting with dementia. Prass, K., Brück, W., Schröder, N.W., Bender, A., Prass, M., Wolf, T., Van der Knaap, M.S., Zschenderlein, R. Ann. Neurol. (2001) [Pubmed]
  7. Adult onset tic disorders. Chouinard, S., Ford, B. J. Neurol. Neurosurg. Psychiatr. (2000) [Pubmed]
  8. Adult onset nocturnal enuresis. Sakamoto, K., Blaivas, J.G. J. Urol. (2001) [Pubmed]
  9. Alcoholism and subtypes of antisocial personality disorder. Hesselbrock, V.M., Hesselbrock, M.N. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. (1994) [Pubmed]
  10. Lamin B1 duplications cause autosomal dominant leukodystrophy. Padiath, Q.S., Saigoh, K., Schiffmann, R., Asahara, H., Yamada, T., Koeppen, A., Hogan, K., Pt??cek, L.J., Fu, Y.H. Nat. Genet. (2006) [Pubmed]
  11. Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. Nachtigall, L.B., Boepple, P.A., Pralong, F.P., Crowley, W.F. N. Engl. J. Med. (1997) [Pubmed]
  12. Adult-onset ataxia and polyneuropathy caused by mitochondrial 8993T-->C mutation. Rantamäki, M.T., Soini, H.K., Finnilä, S.M., Majamaa, K., Udd, B. Ann. Neurol. (2005) [Pubmed]
  13. DYT13, a novel primary torsion dystonia locus, maps to chromosome 1p36.13--36.32 in an Italian family with cranial-cervical or upper limb onset. Valente, E.M., Bentivoglio, A.R., Cassetta, E., Dixon, P.H., Davis, M.B., Ferraris, A., Ialongo, T., Frontali, M., Wood, N.W., Albanese, A. Ann. Neurol. (2001) [Pubmed]
  14. Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Almasy, L., Bressman, S.B., Raymond, D., Kramer, P.L., Greene, P.E., Heiman, G.A., Ford, B., Yount, J., de Leon, D., Chouinard, S., Saunders-Pullman, R., Brin, M.F., Kapoor, R.P., Jones, A.C., Shen, H., Fahn, S., Risch, N.J., Nygaard, T.G. Ann. Neurol. (1997) [Pubmed]
  15. Adult-onset hypothyroidism facilitates and enhances LTD: Reversal by chronic nicotine treatment. Alzoubi, K.H., Aleisa, A.M., Alkadhi, K.A. Neurobiol. Dis. (2007) [Pubmed]
  16. A New Locus (GLC1H) for Adult-Onset Primary Open-angle Glaucoma Maps to the 2p15-p16 Region. Suriyapperuma, S.P., Child, A., Desai, T., Brice, G., Kerr, A., Crick, R.P., Sarfarazi, M. Arch. Ophthalmol. (2007) [Pubmed]
  17. Myasthenia gravis. Pourmand, R. Disease-a-month : DM. (1997) [Pubmed]
  18. A Yorkshire family with adult-onset cranio-cervical primary torsion dystonia. Münchau, A., Valente, E.M., Davis, M.B., Stinton, V., Wood, N.W., Quinn, N.P., Bhatia, K.P. Mov. Disord. (2000) [Pubmed]
  19. Adult onset Niemann-Pick type C disease: A clinical, neuroimaging and molecular genetic study. Battisti, C., Tarugi, P., Dotti, M.T., De Stefano, N., Vattimo, A., Chierichetti, F., Calandra, S., Federico, A. Mov. Disord. (2003) [Pubmed]
  20. A densitometric and morphometric analysis of the skeleton in adults with varying degrees of growth hormone deficiency. Murray, R.D., Adams, J.E., Shalet, S.M. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  21. Evidence of cardiomyocyte necrosis in glycogen storage disease type II. Gaze, D.C., Lawson, G.J., Harris, A., Collinson, P.O. Ann. Clin. Biochem. (2007) [Pubmed]
  22. Adult onset acute myelogenous leukemia and electromagnetic fields in Los Angeles County: bed-heating and occupational exposures. Oppenheimer, M., Preston-Martin, S. Bioelectromagnetics. (2002) [Pubmed]
  23. Regional metabolism in primary torsion dystonia: effects of penetrance and genotype. Carbon, M., Su, S., Dhawan, V., Raymond, D., Bressman, S., Eidelberg, D. Neurology (2004) [Pubmed]
  24. Adult-onset primary lower limb dystonia. Schneider, S.A., Edwards, M.J., Grill, S.E., Goldstein, S., Kanchana, S., Quinn, N.P., Bhatia, K.P., Hallett, M., Reich, S.G. Mov. Disord. (2006) [Pubmed]
  25. Modification of the natural history of adult-onset acid maltase deficiency by nutrition and exercise therapy. Slonim, A.E., Bulone, L., Goldberg, T., Minikes, J., Slonim, E., Galanko, J., Martiniuk, F. Muscle Nerve (2007) [Pubmed]
  26. Adult onset of T-cell deficiency with impaired CD2 expression complicated by Rhodococcus infection: a case report. Kittner, J.M., Jacobs, R., Buyny, S., Peest, D., Stoll, M., Schmidt, R.E. Ann. Allergy Asthma Immunol. (2007) [Pubmed]
  27. Adult onset leucoencephalopathy with brain stem and spinal cord involvement and normal lactate. Petzold, G.C., Bohner, G., Klingebiel, R., Amberger, N., van der Knaap, M.S., Zschenderlein, R. J. Neurol. Neurosurg. Psychiatr. (2006) [Pubmed]
  28. Adult-onset Still's disease: evaluation by gallium-67 citrate scintigraphy. Takeshita, T., Kaminaga, T., Ohkuma, M., Furui, S. Intern. Med. (2006) [Pubmed]
  29. Type II (adult onset) citrullinaemia: clinical pictures and the therapeutic effect of liver transplantation. Ikeda, S., Yazaki, M., Takei, Y., Ikegami, T., Hashikura, Y., Kawasaki, S., Iwai, M., Kobayashi, K., Saheki, T. J. Neurol. Neurosurg. Psychiatr. (2001) [Pubmed]
  30. Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption. Montagnani, M., Love, M.W., Rössel, P., Dawson, P.A., Qvist, P. Scand. J. Gastroenterol. (2001) [Pubmed]
  31. A comparison of adult onset and "classical" idiopathic generalised epilepsy. Nicolson, A., Chadwick, D.W., Smith, D.F. J. Neurol. Neurosurg. Psychiatr. (2004) [Pubmed]
  32. Age of lens use onset in a myopic sample of office-workers. Iribarren, R., Cerrella, M.R., Armesto, A., Iribarren, G., Fornaciari, A. Curr. Eye Res. (2004) [Pubmed]
  33. Adult-onset foveomacular vitelliform dystrophy: a study by optical coherence tomography. Ghazi, N.G. Am. J. Ophthalmol. (2003) [Pubmed]
  34. Adult-onset atopic dermatitis in a patch test population. Ingordo, V., D'Andria, G., D'Andria, C. Dermatology (Basel) (2003) [Pubmed]
  35. Adult onset Langerhans cell histiocytosis of the orbit--a case report. Subramanian, N., Krishnakumar, S., Babu, K., Mohan, R., Lakshmi, K.S., Biswas, J. Orbit (Amsterdam, Netherlands) (2004) [Pubmed]
WikiGenes - Universities