Gene Review:
EPHA3 - EPH receptor A3
Homo sapiens
Synonyms:
EK4, EPH-like kinase 4, ETK, ETK1, Eph-like tyrosine kinase 1, ...
- Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers. Wood, L.D., Calhoun, E.S., Silliman, N., Ptak, J., Szabo, S., Powell, S.M., Riggins, G.J., Wang, T.L., Yan, H., Gazdar, A., Kern, S.E., Pennacchio, L., Kinzler, K.W., Vogelstein, B., Velculescu, V.E. Hum. Mutat. (2006)
- Transcriptional analysis of the human ornithine aminotransferase promoter. Engelhardt, J.F., Steel, G., Valle, D. J. Biol. Chem. (1991)
- GlcNAcstatin: a Picomolar, Selective O-GlcNAcase Inhibitor That Modulates Intracellular O-GlcNAcylation Levels. Dorfmueller, H.C., Borodkin, V.S., Schimpl, M., Shepherd, S.M., Shpiro, N.A., Aalten, D.M. J. Am. Chem. Soc. (2006)
- A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC). Erlandsson, R., Bergerheim, U.S., Boldog, F., Marcsek, Z., Kunimi, K., Lin, B.Y., Ingvarsson, S., Castresana, J.S., Lee, W.H., Lee, E. Oncogene (1990)
- Porcine endogenous retrovirus infects but does not replicate in nonhuman primate primary cells and cell lines. Ritzhaupt, A., Van Der Laan, L.J., Salomon, D.R., Wilson, C.A. J. Virol. (2002)
- Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome. Capell, B.C., Erdos, M.R., Madigan, J.P., Fiordalisi, J.J., Varga, R., Conneely, K.N., Gordon, L.B., Der, C.J., Cox, A.D., Collins, F.S. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. De Miranda, J., Panizzutti, R., Foltyn, V.N., Wolosker, H. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Purification of a ligand for the EPH-like receptor HEK using a biosensor-based affinity detection approach. Lackmann, M., Bucci, T., Mann, R.J., Kravets, L.A., Viney, E., Smith, F., Moritz, R.L., Carter, W., Simpson, R.J., Nicola, N.A., Mackwell, K., Nice, E.C., Wilks, A.F., Boyd, A.W. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Molecular cloning of HEK, the gene encoding a receptor tyrosine kinase expressed by human lymphoid tumor cell lines. Wicks, I.P., Wilkinson, D., Salvaris, E., Boyd, A.W. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines. Lesage, A.S., Wouters, R., Van Gompel, P., Heylen, L., Vanhoenacker, P., Haegeman, G., Luyten, W.H., Leysen, J.E. Br. J. Pharmacol. (1998)
- Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors. Carver, J.M., Mansson, P.E., Cortes-Burgos, L., Shu, J., Zhou, L.M., Howe, J.R., Giordano, T. Brain Res. (1996)
- Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization. Lackmann, M., Oates, A.C., Dottori, M., Smith, F.M., Do, C., Power, M., Kravets, L., Boyd, A.W. J. Biol. Chem. (1998)
- Localization of a human receptor tyrosine kinase (ETK1) to chromosome region 3p11.2. Wicks, I.P., Lapsys, N.M., Baker, E., Campbell, L.J., Boyd, A.W., Sutherland, G.R. Genomics (1994)
- Interaction between the insulin receptor and Grb14: A dynamic study in living cells using BRET. Nouaille, S., Blanquart, C., Zilberfarb, V., Boute, N., Perdereau, D., Burnol, A.F., Issad, T. Biochem. Pharmacol. (2006)
- PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2. Böhme, B., Holtrich, U., Wolf, G., Luzius, H., Grzeschik, K.H., Strebhardt, K., Rübsamen-Waigmann, H. Oncogene (1993)
- Endogenous channels in HEK cells and potential roles in HCN ionic current measurements. Varghese, A., Tenbroek, E.M., Coles, J., Sigg, D.C. Prog. Biophys. Mol. Biol. (2006)
- Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2. Brustugun, O.T., Fladmark, K.E., Doskeland, S.O., Orrenius, S., Zhivotovsky, B. Cell Death Differ. (1998)
- Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study. Buisson, B., Gopalakrishnan, M., Arneric, S.P., Sullivan, J.P., Bertrand, D. J. Neurosci. (1996)
- Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective. Melegari, M., Scaglioni, P.P., Wands, J.R. Hepatology (1998)
- ATP1AL1, a member of the non-gastric H,K-ATPase family, functions as a sodium pump. Grishin, A.V., Caplan, M.J. J. Biol. Chem. (1998)
- Regulation of phosducin-like protein by casein kinase 2 and N-terminal splicing. Humrich, J., Bermel, C., Grubel, T., Quitterer, U., Lohse, M.J. J. Biol. Chem. (2003)
- Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor. Lackmann, M., Mann, R.J., Kravets, L., Smith, F.M., Bucci, T.A., Maxwell, K.F., Howlett, G.J., Olsson, J.E., Vanden Bos, T., Cerretti, D.P., Boyd, A.W. J. Biol. Chem. (1997)
- Telomerase activity is repressed during differentiation along the hepatocytic and biliary epithelial lineages: verification on immortal cell lines from the same origin. Fukutomi, M., Enjoji, M., Iguchi, H., Yokota, M., Iwamoto, H., Nakamuta, M., Sakai, H., Nawata, H. Cell Biochem. Funct. (2001)
- Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4. Grayson, C., Molday, R.S. J. Biol. Chem. (2005)