Gene Review:
FGF3 - fibroblast growth factor 3
Homo sapiens
Synonyms:
FGF-3, Fibroblast growth factor 3, HBGF-3, Heparin-binding growth factor 3, INT2, ...
Holzmann,
Kohlhammer,
Schwaenen,
Wessendorf,
Kestler,
Schwoerer,
Rau,
Radlwimmer,
Döhner,
Lichter,
Gress,
Bentz,
- Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Ropiquet, F., Giri, D., Kwabi-Addo, B., Mansukhani, A., Ittmann, M. Cancer Res. (2000)
- Amplified region of chromosome band 11q13 in breast and squamous cell carcinomas encompasses three CpG islands telomeric of FGF3, including the expressed gene EMS1. Brookes, S., Lammie, G.A., Schuuring, E., de Boer, C., Michalides, R., Dickson, C., Peters, G. Genes Chromosomes Cancer (1993)
- Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays. Mayr, D., Kanitz, V., Anderegg, B., Luthardt, B., Engel, J., Löhrs, U., Amann, G., Diebold, J. Am. J. Clin. Pathol. (2006)
- Fibroblast growth factors and their receptors in parathyroid disease. Lambert, D., Eaton, C.L., Harrison, B.J. World journal of surgery. (1998)
- Cyclin DI amplification is not associated with reduced overall survival in primary breast cancer but may predict early relapse in patients with features of good prognosis. Seshadri, R., Lee, C.S., Hui, R., McCaul, K., Horsfall, D.J., Sutherland, R.L. Clin. Cancer Res. (1996)
- Quantification of oncogene dosage in tumours by simultaneous dual-label hybridization. Stickland, J.E., Tomlinson, I.P., Ramshaw, A.L., Bromley, L., Potter, C.G., McGee, J.O. Oncogene (1993)
- Genetic linkage of vitelliform macular degeneration (Best's disease) to chromosome 11q13. Stone, E.M., Nichols, B.E., Streb, L.M., Kimura, A.E., Sheffield, V.C. Nat. Genet. (1992)
- Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage. Lupetti, R., Pisarra, P., Verrecchia, A., Farina, C., Nicolini, G., Anichini, A., Bordignon, C., Sensi, M., Parmiani, G., Traversari, C. J. Exp. Med. (1998)
- Her-2/neu and INT2 proto-oncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones. Olsson, H., Borg, A., Fernö, M., Ranstam, J., Sigurdsson, H. J. Natl. Cancer Inst. (1991)
- Loss of heterozygosity of markers on chromosome 11 in tumors from patients with multiple endocrine neoplasia syndrome type 1. Radford, D.M., Ashley, S.W., Wells, S.A., Gerhard, D.S. Cancer Res. (1990)
- RAAS polymorphisms alter the acute blood pressure response to aerobic exercise among men with hypertension. Blanchard, B.E., Tsongalis, G.J., Guidry, M.A., Labelle, L.A., Poulin, M., Taylor, A.L., Maresh, C.M., Devaney, J., Thompson, P.D., Pescatello, L.S. Eur. J. Appl. Physiol. (2006)
- NoBP, a nuclear fibroblast growth factor 3 binding protein, is cell cycle regulated and promotes cell growth. Reimers, K., Antoine, M., Zapatka, M., Blecken, V., Dickson, C., Kiefer, P. Mol. Cell. Biol. (2001)
- Loss of heterozygosity and amplification on chromosome 11q in human ovarian cancer. Foulkes, W.D., Campbell, I.G., Stamp, G.W., Trowsdale, J. Br. J. Cancer (1993)
- Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2. Antoine, M., Reimers, K., Wirz, W., Gressner, A.M., Müller, R., Kiefer, P. Biochem. Biophys. Res. Commun. (2005)
- Induction of inner ear fate by FGF3. Vendrell, V., Carnicero, E., Giraldez, F., Alonso, M.T., Schimmang, T. Development (2000)
- Evaluation of the tumorigenic and angiogenic potential of human fibroblast growth factor FGF3 in nude mice. Li, J.J., Friedman-Kien, A.E., Cockerell, C., Nicolaides, A., Liang, S.L., Huang, Y.Q. J. Cancer Res. Clin. Oncol. (1998)
- Regulation of FGF-3 gene expression in tumorigenic and non-tumorigenic clones of a human colon carcinoma cell line. Galdemard, C., Yamagata, H., Brison, O., Lavialle, C. J. Biol. Chem. (2000)
- Growth factors in progression of human esophageal and gastric carcinomas. Yoshida, K., Yasui, W., Ito, H., Tahara, E. Experimental pathology. (1990)
- NH2-terminal cleavage of xenopus fibroblast growth factor 3 is necessary for optimal biological activity and receptor binding. Antoine, M., Daum, M., Köhl, R., Blecken, V., Close, M.J., Peters, G., Kiefer, P. Cell Growth Differ. (2000)
- Int-2/FGF3 amplification is a better independent predictor of relapse than c-myc and c-erbB-2/neu amplifications in primary human breast cancer. Champème, M.H., Bièche, I., Hacène, K., Lidereau, R. Mod. Pathol. (1994)
- Allelic loss from chromosome 11 in parathyroid tumors. Friedman, E., De Marco, L., Gejman, P.V., Norton, J.A., Bale, A.E., Aurbach, G.D., Spiegel, A.M., Marx, S.J. Cancer Res. (1992)
- Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor. Zhang, G., Sato, J.D., Herley, M.T., Tsang, M.W., Ye, H., Liu, H., Ichimura, T., Yan, G., McKeehan, W.L., Stevens, J.L. Cell Growth Differ. (1994)
- Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes. Holzmann, K., Kohlhammer, H., Schwaenen, C., Wessendorf, S., Kestler, H.A., Schwoerer, A., Rau, B., Radlwimmer, B., Döhner, H., Lichter, P., Gress, T., Bentz, M. Cancer Res. (2004)
- Framework YAC contig anchored into a 3.2-Mb high-resolution physical map in proximal 11q13. Courseaux, A., Szepetowski, P., Fernandes, M., Serizet, C., Kawaguchi, Y., Grosgeorge, J., Perucca-Lostanlen, D., Shows, T.B., Todd, J.A., Nowak, N.J., Gaudray, P. Genomics (1997)
- Co-overexpression of fibroblast growth factor 3 and epidermal growth factor receptor is correlated with the development of nonsmall cell lung carcinoma. Tai, A.L., Sham, J.S., Xie, D., Fang, Y., Wu, Y.L., Hu, L., Deng, W., Tsao, G.S., Qiao, G.B., Cheung, A.L., Guan, X.Y. Cancer (2006)
- Nucleolar association of fibroblast growth factor 3 via specific sequence motifs has inhibitory effects on cell growth. Kiefer, P., Dickson, C. Mol. Cell. Biol. (1995)
- Deletion and translocation of chromosome 11q13 sequences in cervical carcinoma cell lines. Jesudasan, R.A., Rahman, R.A., Chandrashekharappa, S., Evans, G.A., Srivatsan, E.S. Am. J. Hum. Genet. (1995)
- Amplification of FGF-related genes in human tumors: possible involvement of HST in breast carcinomas. Theillet, C., Le Roy, X., De Lapeyrière, O., Grosgeorges, J., Adnane, J., Raynaud, S.D., Simony-Lafontaine, J., Goldfarb, M., Escot, C., Birnbaum, D. Oncogene (1989)
- D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1. Lammie, G.A., Fantl, V., Smith, R., Schuuring, E., Brookes, S., Michalides, R., Dickson, C., Arnold, A., Peters, G. Oncogene (1991)