Gene Review:
TYRP1 - tyrosinase-related protein 1
Homo sapiens
Synonyms:
5,6-dihydroxyindole-2-carboxylic acid oxidase, CAS2, CATB, Catalase B, DHICA oxidase, ...
- Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene. Manga, P., Kromberg, J.G., Box, N.F., Sturm, R.A., Jenkins, T., Ramsay, M. Am. J. Hum. Genet. (1997)
- Detection of tyrosinase and tyrosinase-related protein 1 sequences from peripheral blood of melanoma patients using reverse transcription-polymerase chain reaction. Jin, H.Y., Yamashita, T., Minamitsuji, Y., Omori, F., Jimbow, K. J. Dermatol. Sci. (2003)
- Tyrosinase and tyrosinase-related protein 1 require Rab7 for their intracellular transport. Hirosaki, K., Yamashita, T., Wada, I., Jin, H.Y., Jimbow, K. J. Invest. Dermatol. (2002)
- Autoantibodies to tyrosinase-related protein-1 detected in the sera of vitiligo patients using a quantitative radiobinding assay. Kemp, E.H., Waterman, E.A., Gawkrodger, D.J., Watson, P.F., Weetman, A.P. Br. J. Dermatol. (1998)
- Cell-free assays for gamma-secretase activity. McLendon, C., Xin, T., Ziani-Cherif, C., Murphy, M.P., Findlay, K.A., Lewis, P.A., Pinnix, I., Sambamurti, K., Wang, R., Fauq, A., Golde, T.E. FASEB J. (2000)
- Modulation of temperature-sensitive TRP channels. Huang, J., Zhang, X., McNaughton, P.A. Semin. Cell Dev. Biol. (2006)
- Complex translocation in a boy with trichorhinophalangeal syndrome. Sánchez, L.M., Labarta, J.D., De Negrotti, T.C., Migliorini, A.M. J. Med. Genet. (1985)
- Tryptophan levels, excessive exercise, and nutritional status in anorexia nervosa. Favaro, A., Caregaro, L., Burlina, A.B., Santonastaso, P. Psychosomatic medicine. (2000)
- Cytokine mRNA profile of peripheral blood mononuclear cells isolated from individuals with Trypanosoma cruzi chronic infection. Dutra, W.O., Gollob, K.J., Pinto-Dias, J.C., Gazzinelli, G., Correa-Oliveira, R., Coffman, R.L., Carvalho-Parra, J.F. Scand. J. Immunol. (1997)
- A new TRP to kidney disease. Gudermann, T. Nat. Genet. (2005)
- A TRP channel that senses cold stimuli and menthol. Peier, A.M., Moqrich, A., Hergarden, A.C., Reeve, A.J., Andersson, D.A., Story, G.M., Earley, T.J., Dragoni, I., McIntyre, P., Bevan, S., Patapoutian, A. Cell (2002)
- Ectopic expression of MITF, a gene for Waardenburg syndrome type 2, converts fibroblasts to cells with melanocyte characteristics. Tachibana, M., Takeda, K., Nobukuni, Y., Urabe, K., Long, J.E., Meyers, K.A., Aaronson, S.A., Miki, T. Nat. Genet. (1996)
- Alphavirus-based DNA vaccine breaks immunological tolerance by activating innate antiviral pathways. Leitner, W.W., Hwang, L.N., deVeer, M.J., Zhou, A., Silverman, R.H., Williams, B.R., Dubensky, T.W., Ying, H., Restifo, N.P. Nat. Med. (2003)
- TYRP2-mediated resistance to cis-diamminedichloroplatinum (II) in human melanoma cells is independent of tyrosinase and TYRP1 expression and melanin content. Pak, B.J., Li, Q., Kerbel, R.S., Ben-David, Y. Melanoma Res. (2000)
- Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. Wang, R.F., Robbins, P.F., Kawakami, Y., Kang, X.Q., Rosenberg, S.A. J. Exp. Med. (1995)
- alpha-Tocopherol-mediated long-lasting protection against oxidative damage involves an attenuation of calcium entry through TRP-like channels in cultured hippocampal neurons. Crouzin, N., de Jesus Ferreira, M.C., Cohen-Solal, C., Aimar, R.F., Vignes, M., Guiramand, J. Free Radic. Biol. Med. (2007)
- Recent results of health examinations on the general population in cadmium-polluted and control areas in Japan. Shigematsu, I., Minowa, M., Yoshida, T., Miyamoto, K. Environ. Health Perspect. (1979)
- Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family. Sturm, R.A., O'Sullivan, B.J., Box, N.F., Smith, A.G., Smit, S.E., Puttick, E.R., Parsons, P.G., Dunn, I.S. Genomics (1995)
- Oculocutaneous albinism with TYRP1 gene mutations in a Caucasian patient. Rooryck, C., Roudaut, C., Robine, E., Müsebeck, J., Arveiler, B. Pigment Cell Res. (2006)
- A model for melanosome biogenesis based on the purification and analysis of early melanosomes. Kushimoto, T., Basrur, V., Valencia, J., Matsunaga, J., Vieira, W.D., Ferrans, V.J., Muller, J., Appella, E., Hearing, V.J. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Tyrp1 and oculocutaneous albinism type 3. Sarangarajan, R., Boissy, R.E. Pigment Cell Res. (2001)
- Human melanocytes and melanomas express novel mRNA isoforms of the tyrosinase-related protein-2/DOPAchrome tautomerase gene: molecular and functional characterization. Pisarra, P., Lupetti, R., Palumbo, A., Napolitano, A., Prota, G., Parmiani, G., Anichini, A., Sensi, M. J. Invest. Dermatol. (2000)
- Comparison of the melanogenesis in human black and light brown melanocytes. Maeda, K., Yokokawa, Y., Hatao, M., Naganuma, M., Tomita, Y. J. Dermatol. Sci. (1997)
- Quantification of tyrosinase, TRP-1, and Trp-2 transcripts in human melanocytes by reverse transcriptase-competitive multiplex PCR--regulation by steroid hormones. Kippenberger, S., Loitsch, S., Solano, F., Bernd, A., Kaufmann, R. J. Invest. Dermatol. (1998)
- Expression studies of pigmentation and POU-domain genes in human melanoma cells. Sturm, R.A., O'Sullivan, B.J., Thomson, J.A., Jamshidi, N., Pedley, J., Parsons, P.G. Pigment Cell Res. (1994)
- Human melanoma cell lines show little relationship between expression of pigmentation genes and pigmentary behaviour in vitro. Eberle, J., Wagner, M., MacNeil, S. Pigment Cell Res. (1998)
- Differential regulation of melanosomal proteins after hinokitiol treatment. Choi, Y.G., Bae, E.J., Kim, D.S., Park, S.H., Kwon, S.B., Na, J.I., Park, K.C. J. Dermatol. Sci. (2006)
- The expression of melanogenic proteins in Korean skin after ultraviolet irradiation. Kim, T.J., Cho, M.K., Lee, J.S., Whang, K.U., Jin, S.Y., Hoshino, T. J. Dermatol. (2003)
- Genetics of pigment cells: lessons from the tyrosinase gene family. Murisier, F., Beermann, F. Histol. Histopathol. (2006)
- Tyrosinase-related proteins suppress tyrosinase-mediated cell death of melanocytes and melanoma cells. Rad, H.H., Yamashita, T., Jin, H.Y., Hirosaki, K., Wakamatsu, K., Ito, S., Jimbow, K. Exp. Cell Res. (2004)
- Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. Fang, D., Tsuji, Y., Setaluri, V. Nucleic Acids Res. (2002)
- Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3". Boissy, R.E., Zhao, H., Oetting, W.S., Austin, L.M., Wildenberg, S.C., Boissy, Y.L., Zhao, Y., Sturm, R.A., Hearing, V.J., King, R.A., Nordlund, J.J. Am. J. Hum. Genet. (1996)
- Mammalian tyrosinase-related protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. An avian model for human vitiligo. Austin, L.M., Boissy, R.E. Am. J. Pathol. (1995)
- Assignment of the human TYRP (brown) locus to chromosome region 9p23 by nonradioactive in situ hybridization. Murty, V.V., Bouchard, B., Mathew, S., Vijayasaradhi, S., Houghton, A.N. Genomics (1992)