Gene Review:
Rnasel - ribonuclease L (2', 5'-oligoisoadenylate...
Mus musculus
Synonyms:
2-5A-dependent RNAase, 2-5A-dependent RNase, 2-5A-dependent ribonuclease, E230029I04Rik, RNase L, ...
Chandrasekaran,
Mehrabian,
Li,
Hassel,
Guidotti,
Morris,
Mendez,
Koch,
Silverman,
Williams,
Chisari,
Khabar,
Siddiqui,
al-Zoghaibi,
al-Haj,
Dhalla,
Zhou,
Dong,
Whitmore,
Paranjape,
Al-Ahdal,
Al-Mohanna,
Williams,
Silverman,
Ryman,
Meier,
Nangle,
Ragsdale,
Korneeva,
Rhoads,
MacDonald,
Klimstra,
Bisbal,
Silhol,
Laubenthal,
Kaluza,
Carnac,
Milligan,
Le Roy,
Salehzada,
Derrick,
Yang,
Morris,
- Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways. Zhou, A., Paranjape, J.M., Der, S.D., Williams, B.R., Silverman, R.H. Virology (1999)
- Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-beta during acute ocular herpes simplex virus type 1 infection. Austin, B.A., James, C., Silverman, R.H., Carr, D.J. J. Immunol. (2005)
- RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection. Flodström-Tullberg, M., Hultcrantz, M., Stotland, A., Maday, A., Tsai, D., Fine, C., Williams, B., Silverman, R., Sarvetnick, N. J. Immunol. (2005)
- RNase L plays a role in the antiviral response to West Nile virus. Scherbik, S.V., Paranjape, J.M., Stockman, B.M., Silverman, R.H., Brinton, M.A. J. Virol. (2006)
- Expression cloning of 2-5A-dependent RNAase: a uniquely regulated mediator of interferon action. Zhou, A., Hassel, B.A., Silverman, R.H. Cell (1993)
- Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L. Zhou, A., Paranjape, J., Brown, T.L., Nie, H., Naik, S., Dong, B., Chang, A., Trapp, B., Fairchild, R., Colmenares, C., Silverman, R.H. EMBO J. (1997)
- Analogue inhibitor of 2-5A action: effect on the interferon-mediated inhibition of encephalomyocarditis virus replication. Watling, D., Serafinowska, H.T., Reese, C.B., Kerr, I.M. EMBO J. (1985)
- RNase L mediates transient control of the interferon response through modulation of the double-stranded RNA-dependent protein kinase PKR. Khabar, K.S., Siddiqui, Y.M., al-Zoghaibi, F., al-Haj, L., Dhalla, M., Zhou, A., Dong, B., Whitmore, M., Paranjape, J., Al-Ahdal, M.N., Al-Mohanna, F., Williams, B.R., Silverman, R.H. J. Biol. Chem. (2003)
- Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection. Al-Khatib, K., Williams, B.R., Silverman, R.H., Halford, W., Carr, D.J. Exp. Eye Res. (2005)
- Absence of PKR attenuates the anti-HSV-1 activity of an adenoviral vector expressing murine IFN-beta. Al-Khatib, K., Williams, B.R., Silverman, R.H., Halford, W.P., Carr, D.J. J. Interferon Cytokine Res. (2002)
- PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons. Samuel, M.A., Whitby, K., Keller, B.C., Marri, A., Barchet, W., Williams, B.R., Silverman, R.H., Gale, M., Diamond, M.S. J. Virol. (2006)
- Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells. Ryman, K.D., Meier, K.C., Nangle, E.M., Ragsdale, S.L., Korneeva, N.L., Rhoads, R.E., MacDonald, M.R., Klimstra, W.B. J. Virol. (2005)
- The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture. Al-khatib, K., Williams, B.R., Silverman, R.H., Halford, W., Carr, D.J. Virology (2003)
- Effects of PKR/RNase L-dependent and alternative antiviral pathways on alphavirus replication and pathogenesis. Ryman, K.D., White, L.J., Johnston, R.E., Klimstra, W.B. Viral Immunol. (2002)
- The 2'-5' oligoadenylate/RNase L/RNase L inhibitor pathway regulates both MyoD mRNA stability and muscle cell differentiation. Bisbal, C., Silhol, M., Laubenthal, H., Kaluza, T., Carnac, G., Milligan, L., Le Roy, F., Salehzada, T. Mol. Cell. Biol. (2000)
- RNase-L regulates the stability of mitochondrial DNA-encoded mRNAs in mouse embryo fibroblasts. Chandrasekaran, K., Mehrabian, Z., Li, X.L., Hassel, B. Biochem. Biophys. Res. Commun. (2004)
- Mice deficient in oocyte-specific oligoadenylate synthetase-like protein OAS1D display reduced fertility. Yan, W., Ma, L., Stein, P., Pangas, S.A., Burns, K.H., Bai, Y., Schultz, R.M., Matzuk, M.M. Mol. Cell. Biol. (2005)
- 8-Methyladenosine-substituted analogues of 2-5A: synthesis and their biological activities. Kitade, Y., Nakata, Y., Hirota, K., Maki, Y., Pabuccuoglu, A., Torrence, P.F. Nucleic Acids Res. (1991)
- Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice. Guidotti, L.G., Morris, A., Mendez, H., Koch, R., Silverman, R.H., Williams, B.R., Chisari, F.V. J. Virol. (2002)
- Blockade of interferon induction and action by the E3L double-stranded RNA binding proteins of vaccinia virus. Xiang, Y., Condit, R.C., Vijaysri, S., Jacobs, B., Williams, B.R., Silverman, R.H. J. Virol. (2002)
- Activation of NF-kappaB by double-stranded RNA (dsRNA) in the absence of protein kinase R and RNase L demonstrates the existence of two separate dsRNA-triggered antiviral programs. Iordanov, M.S., Wong, J., Bell, J.C., Magun, B.E. Mol. Cell. Biol. (2001)
- Polyclonal antibodies against RNase L. Subcellular localization of this enzyme in mouse cells. Salehzada, T., Silhol, M., Lebleu, B., Bisbal, C. J. Biol. Chem. (1991)
- Cellular and biochemical differences between two attenuated poxvirus vaccine candidates (MVA and NYVAC) and role of the C7L gene. Nájera, J.L., Gómez, C.E., Domingo-Gil, E., Gherardi, M.M., Esteban, M. J. Virol. (2006)
- Vaccination with a Sindbis virus-based DNA vaccine expressing antigen 85B induces protective immunity against Mycobacterium tuberculosis. Derrick, S.C., Yang, A.L., Morris, S.L. Infect. Immun. (2005)