Gene Review:
STX4 - syntaxin 4
Homo sapiens
Synonyms:
Renal carcinoma antigen NY-REN-31, STX4A, Syntaxin-4, p35-2
Smolen,
Hessler,
Nauseef,
Goedken,
Joe,
Knepper,
Inoue,
Band,
Ali,
Vartiainen,
Welti,
Lappalainen,
Olkkonen,
Kuismanen,
Reed,
Houng,
Fitzgerald,
Perskvist,
Roberg,
Kulyté,
Stendahl,
Mollinedo,
Calafat,
Janssen,
Martín-Martín,
Canchado,
Nabokina,
Gajate,
Mollinedo,
Martín-Martín,
Calafat,
Nabokina,
Lazo,
- Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment. Paumet, F., Le Mao, J., Martin, S., Galli, T., David, B., Blank, U., Roa, M. J. Immunol. (2000)
- Regulation of aquaporin-2 water channel trafficking by vasopressin. Knepper, M.A., Inoue, T. Curr. Opin. Cell Biol. (1997)
- Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. Min, J., Okada, S., Kanzaki, M., Elmendorf, J.S., Coker, K.J., Ceresa, B.P., Syu, L.J., Noda, Y., Saltiel, A.R., Pessin, J.E. Mol. Cell (1999)
- Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion. Vicogne, J., Vollenweider, D., Smith, J.R., Huang, P., Frohman, M.A., Pessin, J.E. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs. Fasshauer, D., Sutton, R.B., Brunger, A.T., Jahn, R. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Role of vesicle-associated membrane protein-2, through Q-soluble N-ethylmaleimide-sensitive factor attachment protein receptor/R-soluble N-ethylmaleimide-sensitive factor attachment protein receptor interaction, in the exocytosis of specific and tertiary granules of human neutrophils. Mollinedo, F., Martín-Martín, B., Calafat, J., Nabokina, S.M., Lazo, P.A. J. Immunol. (2003)
- Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell. Saito, T., Okada, S., Yamada, E., Ohshima, K., Shimizu, H., Shimomura, K., Sato, M., Pessin, J.E., Mori, M. J. Biol. Chem. (2003)
- Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion. Reed, G.L., Houng, A.K., Fitzgerald, M.L. Blood (1999)
- Rab5a GTPase regulates fusion between pathogen-containing phagosomes and cytoplasmic organelles in human neutrophils. Perskvist, N., Roberg, K., Kulyté, A., Stendahl, O. J. Cell. Sci. (2002)
- Expression of eosinophil target SNAREs as potential cognate receptors for vesicle-associated membrane protein-2 in exocytosis. Logan, M.R., Lacy, P., Bablitz, B., Moqbel, R. J. Allergy Clin. Immunol. (2002)
- Subcellular distribution of docking/fusion proteins in neutrophils, secretory cells with multiple exocytic compartments. Brumell, J.H., Volchuk, A., Sengelov, H., Borregaard, N., Cieutat, A.M., Bainton, D.F., Grinstein, S., Klip, A. J. Immunol. (1995)
- Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2. Jagadish, M.N., Fernandez, C.S., Hewish, D.R., Macaulay, S.L., Gough, K.H., Grusovin, J., Verkuylen, A., Cosgrove, L., Alafaci, A., Frenkel, M.J., Ward, C.W. Biochem. J. (1996)
- A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils. Logan, M.R., Lacy, P., Odemuyiwa, S.O., Steward, M., Davoine, F., Kita, H., Moqbel, R. Allergy (2006)
- Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. Low, S.H., Vasanji, A., Nanduri, J., He, M., Sharma, N., Koo, M., Drazba, J., Weimbs, T. Mol. Biol. Cell (2006)
- Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets. Chung, S.H., Polgar, J., Reed, G.L. J. Biol. Chem. (2000)
- SNARE protein degradation upon platelet activation: calpain cleaves SNAP-23. Lai, K.C., Flaumenhaft, R. J. Cell. Physiol. (2003)
- Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion. Polgár, J., Chung, S.H., Reed, G.L. Blood (2002)
- Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells. Miyata, T., Ohnishi, H., Suzuki, J., Yoshikumi, Y., Ohno, H., Mashima, H., Yasuda, H., Ishijima, T., Osawa, H., Satoh, K., Sunada, K., Kita, H., Yamamoto, H., Sugano, K. Biochem. Biophys. Res. Commun. (2004)
- Endogenous plasma membrane t-SNARE syntaxin 4 is present in rab11 positive endosomal membranes and associates with cortical actin cytoskeleton. Band, A.M., Ali, H., Vartiainen, M.K., Welti, S., Lappalainen, P., Olkkonen, V.M., Kuismanen, E. FEBS Lett. (2002)
- Phosphorylation of SNAP-23 in activated human platelets. Polgár, J., Lane, W.S., Chung, S.H., Houng, A.K., Reed, G.L. J. Biol. Chem. (2003)
- Interaction of the taxilin family with the nascent polypeptide-associated complex that is involved in the transcriptional and translational processes. Yoshida, K., Nogami, S., Satoh, S., Tanaka-Nakadate, S., Hiraishi, H., Terano, A., Shirataki, H. Genes Cells (2005)
- Combinatorial SNARE complexes modulate the secretion of cytoplasmic granules in human neutrophils. Mollinedo, F., Calafat, J., Janssen, H., Martín-Martín, B., Canchado, J., Nabokina, S.M., Gajate, C. J. Immunol. (2006)
- Pancreatic Acinar Cells Express Vesicle-associated Membrane Protein 2- and 8-Specific Populations of Zymogen Granules with Distinct and Overlapping Roles in Secretion. Weng, N., Thomas, D.D., Groblewski, G.E. J. Biol. Chem. (2007)
- Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression. Fu, J., Naren, A.P., Gao, X., Ahmmed, G.U., Malik, A.B. J. Biol. Chem. (2005)
- Identification and cloning of the SNARE proteins VAMP-2 and syntaxin-4 from HL-60 cells and human neutrophils. Smolen, J.E., Hessler, R.J., Nauseef, W.M., Goedken, M., Joe, Y. Inflammation (2001)
- Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. Tellam, J.T., Macaulay, S.L., McIntosh, S., Hewish, D.R., Ward, C.W., James, D.E. J. Biol. Chem. (1997)