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Gene Review

ZNF1  -  zinc finger protein 1

Homo sapiens

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Disease relevance of ZNF1


High impact information on ZNF1


Biological context of ZNF1


Anatomical context of ZNF1


Associations of ZNF1 with chemical compounds


Regulatory relationships of ZNF1


Other interactions of ZNF1


Analytical, diagnostic and therapeutic context of ZNF1


  1. Zinc finger phage: affinity selection of fingers with new DNA-binding specificities. Rebar, E.J., Pabo, C.O. Science (1994) [Pubmed]
  2. BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci. Pasqualucci, L., Migliazza, A., Fracchiolla, N., William, C., Neri, A., Baldini, L., Chaganti, R.S., Klein, U., Küppers, R., Rajewsky, K., Dalla-Favera, R. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  3. Ciz1, a Novel DNA-Binding Coactivator of the Estrogen Receptor {alpha}, Confers Hypersensitivity to Estrogen Action. den Hollander, P., Rayala, S.K., Coverley, D., Kumar, R. Cancer Res. (2006) [Pubmed]
  4. Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein. David, G., Alland, L., Hong, S.H., Wong, C.W., DePinho, R.A., Dejean, A. Oncogene (1998) [Pubmed]
  5. Zinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transfer. Guo, J., Wu, T., Anderson, J., Kane, B.F., Johnson, D.G., Gorelick, R.J., Henderson, L.E., Levin, J.G. J. Virol. (2000) [Pubmed]
  6. Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Pavletich, N.P., Pabo, C.O. Science (1993) [Pubmed]
  7. The Zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Gierl, M.S., Karoulias, N., Wende, H., Strehle, M., Birchmeier, C. Genes Dev. (2006) [Pubmed]
  8. Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. Bavisotto, L., Kaushansky, K., Lin, N., Hromas, R. J. Exp. Med. (1991) [Pubmed]
  9. ZNF674: A New Kruppel-Associated Box-Containing Zinc-Finger Gene Involved in Nonsyndromic X-Linked Mental Retardation. Lugtenberg, D., Yntema, H.G., Banning, M.J., Oudakker, A.R., Firth, H.V., Willatt, L., Raynaud, M., Kleefstra, T., Fryns, J.P., Ropers, H.H., Chelly, J., Moraine, C., Gecz, J., Reeuwijk, J., Nabuurs, S.B., de Vries, B.B., Hamel, B.C., de Brouwer, A.P., Bokhoven, H. Am. J. Hum. Genet. (2006) [Pubmed]
  10. Multiple modes of RNA recognition by zinc finger proteins. Hall, T.M. Curr. Opin. Struct. Biol. (2005) [Pubmed]
  11. Zinc finger proteins: new insights into structural and functional diversity. Laity, J.H., Lee, B.M., Wright, P.E. Curr. Opin. Struct. Biol. (2001) [Pubmed]
  12. Toward rules relating zinc finger protein sequences and DNA binding site preferences. Desjarlais, J.R., Berg, J.M. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  13. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. Huebner, K., Druck, T., Croce, C.M., Thiesen, H.J. Am. J. Hum. Genet. (1991) [Pubmed]
  14. Zinc finger point mutations within the WT1 gene in Wilms tumor patients. Little, M.H., Prosser, J., Condie, A., Smith, P.J., Van Heyningen, V., Hastie, N.D. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  15. Mapping and initial analysis of human subtelomeric sequence assemblies. Riethman, H., Ambrosini, A., Castaneda, C., Finklestein, J., Hu, X.L., Mudunuri, U., Paul, S., Wei, J. Genome Res. (2004) [Pubmed]
  16. Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas. Tam, W., Gomez, M., Chadburn, A., Lee, J.W., Chan, W.C., Knowles, D.M. Blood (2006) [Pubmed]
  17. Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions. Hirata, T., Nakazawa, M., Muraoka, O., Nakayama, R., Suda, Y., Hibi, M. Development (2006) [Pubmed]
  18. Gli proteins and the control of spinal-cord patterning. Jacob, J., Briscoe, J. EMBO Rep. (2003) [Pubmed]
  19. A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth. Hattori, T., Baba, K., Matsuzaki, S., Honda, A., Miyoshi, K., Inoue, K., Taniguchi, M., Hashimoto, H., Shintani, N., Baba, A., Shimizu, S., Yukioka, F., Kumamoto, N., Yamaguchi, A., Tohyama, M., Katayama, T. Mol. Psychiatry (2007) [Pubmed]
  20. Induction of the 'zinc finger' gene after transient focal ischemia in rat cerebral cortex. Abe, K., Kawagoe, J., Sato, S., Sahara, M., Kogure, K. Neurosci. Lett. (1991) [Pubmed]
  21. Inhibition of Growth Hormone Receptor Gene Expression by Saturated Fatty Acids: Role of Kruppel-Like Zinc Finger Factor, ZBP-89. Thimmarayappa, J., Sun, J., Schultz, L.E., Dejkhamron, P., Lu, C., Giallongo, A., Merchant, J.L., Menon, R.K. Mol. Endocrinol. (2006) [Pubmed]
  22. Engineered zinc finger proteins that respond to DNA modification by HaeIII and HhaI methyltransferase enzymes. Isalan, M., Choo, Y. J. Mol. Biol. (2000) [Pubmed]
  23. Functional characterization of zinc-finger motif in redox regulation of RPA-ssDNA interaction. You, J.S., Wang, M., Lee, S.H. Biochemistry (2000) [Pubmed]
  24. Oxidation of zinc finger transcription factors: physiological consequences. Webster, K.A., Prentice, H., Bishopric, N.H. Antioxid. Redox Signal. (2001) [Pubmed]
  25. Comparative gene expression study to identify genes possibly related to storage root formation in cassava. de Souza, C.R., Carvalho, L.J., de Mattos Cascardo, J.C. Protein Pept. Lett. (2004) [Pubmed]
  26. An RNF11: Smurf2 complex mediates ubiquitination of the AMSH protein. Li, H., Seth, A. Oncogene (2004) [Pubmed]
  27. Zinc finger transcription factor Egr-1 activates Flt-1 gene expression in THP-1 cells on induction for macrophage differentiation. Akuzawa, N., Kurabayashi, M., Ohyama, Y., Arai, M., Nagai, R. Arterioscler. Thromb. Vasc. Biol. (2000) [Pubmed]
  28. Mammalian gene targeting with designed zinc finger nucleases. Porteus, M.H. Mol. Ther. (2006) [Pubmed]
  29. Identification and Characterization of the Human SCAN Domain Zinc-Finger Gene ZNF449. Luo, K., Li, J., Cui, Y., Xu, M., Yuan, J., Tang, W., Wan, B., Yu, L. Mol. Biol. Rep. (2006) [Pubmed]
  30. Zinc finger 81 (ZNF81) mutations associated with X-linked mental retardation. Kleefstra, T., Yntema, H.G., Oudakker, A.R., Banning, M.J., Kalscheuer, V.M., Chelly, J., Moraine, C., Ropers, H.H., Fryns, J.P., Janssen, I.M., Sistermans, E.A., Nillesen, W.N., de Vries, L.B., Hamel, B.C., van Bokhoven, H. J. Med. Genet. (2004) [Pubmed]
  31. Identification of a functionally impaired positive regulatory domain I binding factor 1 transcription repressor in myeloma cell lines. Györy, I., Fejér, G., Ghosh, N., Seto, E., Wright, K.L. J. Immunol. (2003) [Pubmed]
  32. Regulation of epithelial cell growth by ZBP-89: potential relevance in pancreatic cancer. Bai, L., Logsdon, C., Merchant, J.L. International journal of gastrointestinal cancer. (2002) [Pubmed]
  33. Specific Recognition of ZNF217 and Other Zinc Finger Proteins at a Surface Groove of C-Terminal Binding Proteins. Quinlan, K.G., Nardini, M., Verger, A., Francescato, P., Yaswen, P., Corda, D., Bolognesi, M., Crossley, M. Mol. Cell. Biol. (2006) [Pubmed]
  34. Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters. Vural, B., Chen, L.C., Saip, P., Chen, Y.T., Ustuner, Z., Gonen, M., Simpson, A.J., Old, L.J., Ozbek, U., Gure, A.O. Cancer (2005) [Pubmed]
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