Gene Review:
DISC1 - disrupted in schizophrenia 1
Homo sapiens
Synonyms:
C1orf136, Disrupted in schizophrenia 1 protein, KIAA0457, SCZD9
- Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Miyoshi, K., Honda, A., Baba, K., Taniguchi, M., Oono, K., Fujita, T., Kuroda, S., Katayama, T., Tohyama, M. Mol. Psychiatry (2003)
- Localized wedge-shaped defects of retinal nerve fiber layer and disc hemorrhage in glaucoma. Sugiyama, K., Uchida, H., Tomita, G., Sato, Y., Iwase, A., Kitazawa, Y. Ophthalmology (1999)
- Prevalence of Heterotopic Ossification Following Total Disc Replacement. A Prospective, Randomized Study of Two Hundred and Seventy-six Patients. Tortolani, P.J., Cunningham, B.W., Eng, M., McAfee, P.C., Holsapple, G.A., Adams, K.A. The Journal of bone and joint surgery. American volume (2007)
- An AOA critical issue. Disc replacements: this time will we really cure low-back and neck pain? Boden, S.D., Balderston, R.A., Heller, J.G., Hanley, E.N., Zigler, J.E. The Journal of bone and joint surgery. American volume. (2004)
- Growth-inhibitory effects of Galla Rhois-derived tannins on intestinal bacteria. Ahn, Y.J., Lee, C.O., Kweon, J.H., Ahn, J.W., Park, J.H. J. Appl. Microbiol. (1998)
- Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population. Thomson, P.A., Wray, N.R., Millar, J.K., Evans, K.L., Hellard, S.L., Condie, A., Muir, W.J., Blackwood, D.H., Porteous, D.J. Mol. Psychiatry (2005)
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. Blackwood, D.H., Fordyce, A., Walker, M.T., St Clair, D.M., Porteous, D.J., Muir, W.J. Am. J. Hum. Genet. (2001)
- Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13. Hamshere, M.L., Bennett, P., Williams, N., Segurado, R., Cardno, A., Norton, N., Lambert, D., Williams, H., Kirov, G., Corvin, A., Holmans, P., Jones, L., Jones, I., Gill, M., O'Donovan, M.C., Owen, M.J., Craddock, N. Arch. Gen. Psychiatry (2005)
- A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Sawamura, N., Sawamura-Yamamoto, T., Ozeki, Y., Ross, C.A., Sawa, A. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Disrupted-in-Schizophrenia-1 (DISC1): A Key Susceptibility Factor for Major Mental Illnesses. Sawamura, N., Sawa, A. Ann. N. Y. Acad. Sci. (2006)
- Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Cannon, T.D., Hennah, W., van Erp, T.G., Thompson, P.M., Lonnqvist, J., Huttunen, M., Gasperoni, T., Tuulio-Henriksson, A., Pirkola, T., Toga, A.W., Kaprio, J., Mazziotta, J., Peltonen, L. Arch. Gen. Psychiatry (2005)
- Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Callicott, J.H., Straub, R.E., Pezawas, L., Egan, M.F., Mattay, V.S., Hariri, A.R., Verchinski, B.A., Meyer-Lindenberg, A., Balkissoon, R., Kolachana, B., Goldberg, T.E., Weinberger, D.R. Proc. Natl. Acad. Sci. U.S.A. (2005)
- In-vitro biological evaluation of some ONS and NS donor Schiff's bases and their metal complexes. Panchal, P.K., Pansuriya, P.B., Patel, M.N. Journal of enzyme inhibition and medicinal chemistry. (2006)
- Delivery and activity of antimicrobial drugs released from human fibrin sealant. Boyce, S.T., Holder, I.A., Supp, A.P., Warden, G.D., Greenhalgh, D.G. The Journal of burn care & rehabilitation. (1994)
- Mueller-Hinton agar is superior to PDM blood agar for detection of methicillin-resistant Staphylococcus aureus. Monsen, T., Persson, S., Edebro, H., Granström, S., Wiström, J. Clin. Microbiol. Infect. (2003)
- Disruption of two novel genes by a translocation co-segregating with schizophrenia. Millar, J.K., Wilson-Annan, J.C., Anderson, S., Christie, S., Taylor, M.S., Semple, C.A., Devon, R.S., Clair, D.M., Muir, W.J., Blackwood, D.H., Porteous, D.J. Hum. Mol. Genet. (2000)
- Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects. Hennah, W., Varilo, T., Kestilä, M., Paunio, T., Arajärvi, R., Haukka, J., Parker, A., Martin, R., Levitzky, S., Partonen, T., Meyer, J., Lönnqvist, J., Peltonen, L., Ekelund, J. Hum. Mol. Genet. (2003)
- Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia. Millar, J.K., Christie, S., Semple, C.A., Porteous, D.J. Genomics (2000)
- DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Morris, J.A., Kandpal, G., Ma, L., Austin, C.P. Hum. Mol. Genet. (2003)
- DISC1 localizes to the centrosome by binding to kendrin. Miyoshi, K., Asanuma, M., Miyazaki, I., Diaz-Corrales, F.J., Katayama, T., Tohyama, M., Ogawa, N. Biochem. Biophys. Res. Commun. (2004)
- Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site. Brandon, N.J., Schurov, I., Camargo, L.M., Handford, E.J., Duran-Jimeniz, B., Hunt, P., Millar, J.K., Porteous, D.J., Shearman, M.S., Whiting, P.J. Mol. Cell. Neurosci. (2005)
- Comparison of three standardized disc susceptibility testing methods for colistin. Tan, T.Y., Ng, L.S. J. Antimicrob. Chemother. (2006)
- Effect of mechanical cycling on the flexural strength of densely sintered ceramics. Itinoche, K.M., Ozcan, M., Bottino, M.A., Oyafuso, D. Dental materials : official publication of the Academy of Dental Materials. (2006)
- Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs. Lipska, B.K., Peters, T., Hyde, T.M., Halim, N., Horowitz, C., Mitkus, S., Weickert, C.S., Matsumoto, M., Sawa, A., Straub, R.E., Vakkalanka, R., Herman, M.M., Weinberger, D.R., Kleinman, J.E. Hum. Mol. Genet. (2006)
- A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth. Hattori, T., Baba, K., Matsuzaki, S., Honda, A., Miyoshi, K., Inoue, K., Taniguchi, M., Hashimoto, H., Shintani, N., Baba, A., Shimizu, S., Yukioka, F., Kumamoto, N., Yamaguchi, A., Tohyama, M., Katayama, T. Mol. Psychiatry (2007)
- DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Taya, S., Shinoda, T., Tsuboi, D., Asaki, J., Nagai, K., Hikita, T., Kuroda, S., Kuroda, K., Shimizu, M., Hirotsune, S., Iwamatsu, A., Kaibuchi, K. J. Neurosci. (2007)
- DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2. Shinoda, T., Taya, S., Tsuboi, D., Hikita, T., Matsuzawa, R., Kuroda, S., Iwamatsu, A., Kaibuchi, K. J. Neurosci. (2007)
- DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Morris, J.A., Kandpal, G., Ma, L., Austin, C.P. Hum. Mol. Genet. (2003)
- DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain. Austin, C.P., Ma, L., Ky, B., Morris, J.A., Shughrue, P.J. Neuroreport (2003)
- Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Ozeki, Y., Tomoda, T., Kleiderlein, J., Kamiya, A., Bord, L., Fujii, K., Okawa, M., Yamada, N., Hatten, M.E., Snyder, S.H., Ross, C.A., Sawa, A. Proc. Natl. Acad. Sci. U. S. A. (2003)
- Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Miyoshi, K., Honda, A., Baba, K., Taniguchi, M., Oono, K., Fujita, T., Kuroda, S., Katayama, T., Tohyama, M. Mol. Psychiatry. (2003)
- A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Ishizuka, K., Paek, M., Kamiya, A., Sawa, A. Biol. Psychiatry (2006)
- Schizophrenia in Translation: Disrupted in Schizophrenia (DISC1): Integrating Clinical and Basic Findings. Roberts, R.C. Schizophrenia bulletin (2007)
- Preliminary clinical experience with the Bryan Cervical Disc Prosthesis. Goffin, J., Casey, A., Kehr, P., Liebig, K., Lind, B., Logroscino, C., Pointillart, V., Van Calenbergh, F., van Loon, J. Neurosurgery (2002)