Gene Review:
USP6 - ubiquitin specific peptidase 6
Homo sapiens
Synonyms:
Deubiquitinating enzyme 6, HRP1, Proto-oncogene TRE-2, TRE17, TRE2, ...
Oliveira,
Perez-Atayde,
Dal Cin,
Gebhardt,
Chen,
Neff,
Demetri,
Rosenberg,
Bridge,
Fletcher,
Oliveira,
Perez-Atayde,
Inwards,
Medeiros,
Derr,
Hsi,
Gebhardt,
Rosenberg,
Fletcher,
Bizimungu,
De Neve,
Burny,
Bach,
Bontemps,
Portetelle,
Vandenbol,
Takahashi,
Asano,
Kinouchi,
Ishida-Yamamoto,
Wuepper,
Iizuka,
Oliveira,
Hsi,
Weremowicz,
Rosenberg,
Dal Cin,
Joseph,
Bridge,
Perez-Atayde,
Fletcher,
Osada,
Tatematsu,
Masuda,
Saito,
Sugiyama,
Yanagisawa,
Takahashi,
- USP6 and CDH11 oncogenes identify the neoplastic cell in primary aneurysmal bone cysts and are absent in so-called secondary aneurysmal bone cysts. Oliveira, A.M., Perez-Atayde, A.R., Inwards, C.Y., Medeiros, F., Derr, V., Hsi, B.L., Gebhardt, M.C., Rosenberg, A.E., Fletcher, J.A. Am. J. Pathol. (2004)
- USP6 (Tre2) fusion oncogenes in aneurysmal bone cyst. Oliveira, A.M., Hsi, B.L., Weremowicz, S., Rosenberg, A.E., Dal Cin, P., Joseph, N., Bridge, J.A., Perez-Atayde, A.R., Fletcher, J.A. Cancer Res. (2004)
- Identification of novel sequences in the repertoire of hypervariable TRE17 genes from immortalized nonmalignant and malignant human keratinocytes. Onno, M., Nakamura, T., Hillova, J., Hill, M. Gene (1993)
- A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat. Marriott, S.J., Lindholm, P.F., Brown, K.M., Gitlin, S.D., Duvall, J.F., Radonovich, M.F., Brady, J.N. Mol. Cell. Biol. (1990)
- Heterogeneous transforming growth factor (TGF)-beta unresponsiveness and loss of TGF-beta receptor type II expression caused by histone deacetylation in lung cancer cell lines. Osada, H., Tatematsu, Y., Masuda, A., Saito, T., Sugiyama, M., Yanagisawa, K., Takahashi, T. Cancer Res. (2001)
- Grabbing the message: structural basis of mRNA 3'UTR recognition by Hrp1. Pérez-Cañadillas, J.M. EMBO J. (2006)
- The Tre2 (USP6) oncogene is a hominoid-specific gene. Paulding, C.A., Ruvolo, M., Haber, D.A. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Identification of thyroid hormone response elements in the human fatty acid synthase promoter. Xiong, S., Chirala, S.S., Hsu, M.H., Wakil, S.J. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Decreased ratio of total progesterone to total estradiol receptor levels in endometria of women with adult dysfunctional uterine bleeding. Gorodeski, I.G., Geier, A., Siegal, A., Beery, R., Lunenfeld, B., Langzam, J., Bahari, C.M. Gynecol. Obstet. Invest. (1986)
- Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150, and OMD genes. Oliveira, A.M., Perez-Atayde, A.R., Dal Cin, P., Gebhardt, M.C., Chen, C.J., Neff, J.R., Demetri, G.D., Rosenberg, A.E., Bridge, J.A., Fletcher, J.A. Oncogene (2005)
- Calcium/calmodulin regulates ubiquitination of the ubiquitin-specific protease TRE17/USP6. Shen, C., Ye, Y., Robertson, S.E., Lau, A.W., Mak, D.O., Chou, M.M. J. Biol. Chem. (2005)
- Evidence for involvement of TRE-2 (USP6) oncogene, low-copy repeat and acrocentric heterochromatin in two families with chromosomal translocations. Ou, Z., Jarmuz, M., Sparagana, S.P., Michaud, J., Décarie, J.C., Yatsenko, S.A., Nowakowska, B., Furman, P., Shaw, C.A., Shaffer, L.G., Lupski, J.R., Chinault, A.C., Cheung, S.W., Stankiewicz, P. Hum. Genet. (2006)
- The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. Masuda-Robens, J.M., Kutney, S.N., Qi, H., Chou, M.M. Mol. Cell. Biol. (2003)
- Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. Shi, F., Soares, M.J., Avery, M., Liu, F., Zhang, X., Audus, K.L. Exp. Cell Res. (1997)
- Expression in a RabGAP yeast mutant of two human homologues, one of which is an oncogene. Bizimungu, C., De Neve, N., Burny, A., Bach, S., Bontemps, F., Portetelle, D., Vandenbol, M. Biochem. Biophys. Res. Commun. (2003)
- Further characterization of thyroid hormone response elements in the human type 1 iodothyronine deiodinase gene. Zhang, C.Y., Kim, S., Harney, J.W., Larsen, P.R. Endocrinology (1998)
- Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. Itoh, T., Satoh, M., Kanno, E., Fukuda, M. Genes Cells (2006)
- The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Martinu, L., Masuda-Robens, J.M., Robertson, S.E., Santy, L.C., Casanova, J.E., Chou, M.M. Mol. Cell. Biol. (2004)
- Structure and transcriptional regulation of the human cystatin A gene. The 12-O-tetradecanoylphorbol-13-acetate (TPA) responsive element-2 site (-272 to -278) on cystatin A gene is critical for TPA-dependent regulation. Takahashi, H., Asano, K., Kinouchi, M., Ishida-Yamamoto, A., Wuepper, K.D., Iizuka, H. J. Biol. Chem. (1998)
- Transforming growth factor-beta induces differentiation of the labyrinthine trophoblast stem cell line SM10. Selesniemi, K., Reedy, M., Gultice, A., Guilbert, L.J., Brown, T.L. Stem Cells Dev. (2005)
- Novel method for isolating mammalian cells defective in fluid-phase endocytosis. Wang, R.H., Colbaugh, P.A., Kuo, P., Bau, M.Y., Poppe, L.M., Draper, R.K. Somat. Cell Mol. Genet. (1992)
- New controller for functional electrical stimulation systems. Fisekovic, N., Popovic, D.B. Medical engineering & physics. (2001)