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MeSH Review

Leukemia, Lymphocytic

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Disease relevance of Leukemia, Lymphocytic


High impact information on Leukemia, Lymphocytic


Chemical compound and disease context of Leukemia, Lymphocytic


Biological context of Leukemia, Lymphocytic


Anatomical context of Leukemia, Lymphocytic


Gene context of Leukemia, Lymphocytic


Analytical, diagnostic and therapeutic context of Leukemia, Lymphocytic


  1. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. Pear, W.S., Aster, J.C., Scott, M.L., Hasserjian, R.P., Soffer, B., Sklar, J., Baltimore, D. J. Exp. Med. (1996) [Pubmed]
  2. The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. Li, S., Ilaria, R.L., Million, R.P., Daley, G.Q., Van Etten, R.A. J. Exp. Med. (1999) [Pubmed]
  3. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Wiemels, J.L., Smith, R.N., Taylor, G.M., Eden, O.B., Alexander, F.E., Greaves, M.F. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  4. Disparate affinities of antifolates for folylpolyglutamate synthetase from human leukemia cells. Longo, G.S., Gorlick, R., Tong, W.P., Ercikan, E., Bertino, J.R. Blood (1997) [Pubmed]
  5. Allogeneic bone marrow transplantation for leukemia with marrow grafts depleted of lymphocytes by counterflow centrifugation. Schattenberg, A., De Witte, T., Preijers, F., Raemaekers, J., Muus, P., Van der Lely, N., Boezeman, J., Wessels, J., Van Dijk, B., Hoogenhout, J. Blood (1990) [Pubmed]
  6. Src kinases in Ph+ lymphoblastic leukemia. Deininger, M. Nat. Genet. (2004) [Pubmed]
  7. Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Smith, K.S., Chanda, S.K., Lingbeek, M., Ross, D.T., Botstein, D., van Lohuizen, M., Cleary, M.L. Mol. Cell (2003) [Pubmed]
  8. Interleukin 10 induces apoptotic cell death of B-chronic lymphocytic leukemia cells. Fluckiger, A.C., Durand, I., Banchereau, J. J. Exp. Med. (1994) [Pubmed]
  9. TYK2 is a key regulator of the surveillance of B lymphoid tumors. Stoiber, D., Kovacic, B., Schuster, C., Schellack, C., Karaghiosoff, M., Kreibich, R., Weisz, E., Artwohl, M., Kleine, O.C., Muller, M., Baumgartner-Parzer, S., Ghysdael, J., Freissmuth, M., Sexl, V. J. Clin. Invest. (2004) [Pubmed]
  10. Leucovorin enhances cytotoxicity of trimetrexate/fluorouracil, but not methotrexate/fluorouracil, in CCRF-CEM cells. Romanini, A., Li, W.W., Colofiore, J.R., Bertino, J.R. J. Natl. Cancer Inst. (1992) [Pubmed]
  11. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay. Rots, M.G., Pieters, R., Kaspers, G.J., van Zantwijk, C.H., Noordhuis, P., Mauritz, R., Veerman, A.J., Jansen, G., Peters, G.J. Blood (1999) [Pubmed]
  12. Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis. Jones, D.T., Ganeshaguru, K., Anderson, R.J., Jackson, T.R., Bruckdorfer, K.R., Low, S.Y., Palmqvist, L., Prentice, H.G., Hoffbrand, A.V., Mehta, A.B., Wickremasinghe, R.G. Blood (2003) [Pubmed]
  13. A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Ottmann, O.G., Druker, B.J., Sawyers, C.L., Goldman, J.M., Reiffers, J., Silver, R.T., Tura, S., Fischer, T., Deininger, M.W., Schiffer, C.A., Baccarani, M., Gratwohl, A., Hochhaus, A., Hoelzer, D., Fernandes-Reese, S., Gathmann, I., Capdeville, R., O'Brien, S.G. Blood (2002) [Pubmed]
  14. Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells. Berman, E., McBride, M. Blood (1992) [Pubmed]
  15. c-fos oncogene expression in human hematopoietic malignancies is restricted to acute leukemias with monocytic phenotype and to subsets of B cell leukemias. Pinto, A., Colletta, G., Del Vecchio, L., Rosati, R., Attadia, V., Cimino, R., Colombatti, A. Blood (1987) [Pubmed]
  16. Glucocorticosteroids induce DNA fragmentation in human lymphoid leukemia cells. Distelhorst, C.W. Blood (1988) [Pubmed]
  17. Mutations of the p53 and ras genes in childhood t(1;19)-acute lymphoblastic leukemia. Kawamura, M., Kikuchi, A., Kobayashi, S., Hanada, R., Yamamoto, K., Horibe, K., Shikano, T., Ueda, K., Hayashi, K., Sekiya, T. Blood (1995) [Pubmed]
  18. Absence of oncogene amplifications and occasional activation of N-ras in lymphoblastic leukemia of childhood. Rodenhuis, S., Bos, J.L., Slater, R.M., Behrendt, H., van 't Veer, M., Smets, L.A. Blood (1986) [Pubmed]
  19. MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells. Shonai, T., Adachi, M., Sakata, K., Takekawa, M., Endo, T., Imai, K., Hareyama, M. Cell Death Differ. (2002) [Pubmed]
  20. Immunotherapy using unconjugated CD19 monoclonal antibodies in animal models for B lymphocyte malignancies and autoimmune disease. Yazawa, N., Hamaguchi, Y., Poe, J.C., Tedder, T.F. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  21. Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I. Grossman, W.J., Kimata, J.T., Wong, F.H., Zutter, M., Ley, T.J., Ratner, L. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  22. Establishment of a karyotypically normal cytotoxic leukemic T-cell line from a T-ALL sample engrafted in SCID mice. Cesano, A., O'Connor, R., Nowell, P.C., Lange, B., Clark, S.C., Santoli, D. Blood (1993) [Pubmed]
  23. Analysis of the human CD10/neutral endopeptidase 24.11 promoter region: two separate regulatory elements. Ishimaru, F., Shipp, M.A. Blood (1995) [Pubmed]
  24. Apoptosis or plasma cell differentiation of CD38-positive B-chronic lymphocytic leukemia cells induced by cross-linking of surface IgM or IgD. Zupo, S., Massara, R., Dono, M., Rossi, E., Malavasi, F., Cosulich, M.E., Ferrarini, M. Blood (2000) [Pubmed]
  25. c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Luo, H., Li, Q., O'Neal, J., Kreisel, F., Le Beau, M.M., Tomasson, M.H. Blood (2005) [Pubmed]
  26. Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias. Carow, C.E., Levenstein, M., Kaufmann, S.H., Chen, J., Amin, S., Rockwell, P., Witte, L., Borowitz, M.J., Civin, C.I., Small, D. Blood (1996) [Pubmed]
  27. Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13). Cools, J., Mentens, N., Odero, M.D., Peeters, P., Wlodarska, I., Delforge, M., Hagemeijer, A., Marynen, P. Blood (2002) [Pubmed]
  28. Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112). Pende, D., Spaggiari, G.M., Marcenaro, S., Martini, S., Rivera, P., Capobianco, A., Falco, M., Lanino, E., Pierri, I., Zambello, R., Bacigalupo, A., Mingari, M.C., Moretta, A., Moretta, L. Blood (2005) [Pubmed]
  29. Human gamma delta-T lymphocytes express and synthesize connective tissue growth factor: effect of IL-15 and TGF-beta 1 and comparison with alpha beta-T lymphocytes. Workalemahu, G., Foerster, M., Kroegel, C., Braun, R.K. J. Immunol. (2003) [Pubmed]
  30. Normal human pluripotential and committed hematopoietic progenitors do not express the p24 antigen detected by monoclonal antibody BA-2: implications for immunotherapy of lymphocytic leukemia. Ash, R.C., Jansen, J., Kersey, J.H., LeBien, T.W., Zanjani, E.D. Blood (1982) [Pubmed]
  31. Enzymologic classification of acute leukemias: nonspecific esterase markers distinguish myeloid and lymphoid varieties. Yourno, J., Burkart, P., Lizzi, F., Tartaglia, A. Blood (1982) [Pubmed]
  32. Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia. Lennard, L., Lilleyman, J.S. J. Clin. Oncol. (1989) [Pubmed]
  33. In vitro induction of myeloid leukemia-specific CD4 and CD8 T cells by CD40 ligand-activated B cells gene modified to express primary granule proteins. Fujiwara, H., Melenhorst, J.J., El Ouriaghli, F., Kajigaya, S., Grube, M., Sconocchia, G., Rezvani, K., Price, D.A., Hensel, N.F., Douek, D.C., Barrett, A.J. Clin. Cancer Res. (2005) [Pubmed]
  34. A novel protein complex distinct from mismatch repair binds thioguanylated DNA. Krynetski, E.Y., Krynetskaia, N.F., Gallo, A.E., Murti, K.G., Evans, W.E. Mol. Pharmacol. (2001) [Pubmed]
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