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Chemical Compound Review

SureCN76633     naphthalen-1-yl ethanoate

Synonyms: NSC-9846, AG-H-32058, ACMC-209pr7, N8505_SIGMA, ANW-37649, ...
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Disease relevance of Naphthyl acetate


High impact information on Naphthyl acetate


Chemical compound and disease context of Naphthyl acetate


Biological context of Naphthyl acetate


Anatomical context of Naphthyl acetate


Associations of Naphthyl acetate with other chemical compounds


Gene context of Naphthyl acetate

  • Maturation was also observed in other differentiation characteristics such as phagocytic activity, a-naphthyl acetate esterase activity, and expression of surface antigen CD14 [29].
  • JHE also hydrolyses the artificial substrate alpha-naphthyl acetate with a KM of 120 micro M and a Vmax of at least 70 mumol/min/mg [30].
  • The cytochemical investigation of myeloperoxidase (MPO), Sudan black B (SBB), chloroacetate esterase (CAE), alpha-naphthyl butyrate esterase (ANBE), alpha-naphthyl acetate esterase (ANAE) and acid phosphatase (AP) in peripheral blood and/or bone marrow was performed [31].
  • With three of the substrates (alpha-naphthyl acetate and esters 2 and 3), esterase activity was the same in both groups; however, with the others (rho-nitrophenyl acetate and esters 1 and 4), there was a small increase in activity in ovariectomized females, compared with intact females [32].
  • The TNF treated cells were classified as macrophage-like by morphology, and by lineage-specific alpha-naphthyl acetate esterase stain [33].

Analytical, diagnostic and therapeutic context of Naphthyl acetate


  1. Electrophoretic and cytochemical characterization of alpha-naphthyl acetate esterases in acute myeloid leukemia: relationships with membrane receptor and monocyte-specific antigen expression. Scott, C.S., Linch, D.C., Bynoe, A.G., Allen, C., Hogg, N., Ainley, M.J., Hough, D., Roberts, B.E. Blood (1984) [Pubmed]
  2. Acid hydrolases as markers of maturation in B-cell chronic lymphocytic leukemia. Grossi, C.E., Zicca, A., Leprini, A., Cadoni, A., Pistoia, V., Ferrarini, M. Blood (1982) [Pubmed]
  3. TCL1 is overexpressed in patients affected by adult T-cell leukemias. Narducci, M.G., Stoppacciaro, A., Imada, K., Uchiyama, T., Virgilio, L., Lazzeri, C., Croce, C.M., Russo, G. Cancer Res. (1997) [Pubmed]
  4. alpha-Naphthyl acetate esterase activity--a cytochemical marker for T lymphocytees. Correlation with immunologic studies of normal tissues, lymphocytic leukemias, non-Hodgkin's lymphomas, Hodgkin's disease, and other lymphoproliferative disorders. Pinkus, G.S., Hargreaves, H.K., McLeod, J.A., Nadler, L.M., Rosenthal, D.S., Said, J.W. Am. J. Pathol. (1979) [Pubmed]
  5. Fluorescence detection of proteins in sodium dodecyl sulfate-polyacrylamide gels using environmentally benign, nonfixative, saline solution. Steinberg, T.H., Lauber, W.M., Berggren, K., Kemper, C., Yue, S., Patton, W.F. Electrophoresis (2000) [Pubmed]
  6. Gamma interferon induces monocytoid differentiation in the HL-60 cell line. Ball, E.D., Guyre, P.M., Shen, L., Glynn, J.M., Maliszewski, C.R., Baker, P.E., Fanger, M.W. J. Clin. Invest. (1984) [Pubmed]
  7. Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells. Stone, R.M., Sariban, E., Pettit, G.R., Kufe, D.W. Blood (1988) [Pubmed]
  8. Differences in nonspecific esterase from normal and leukemic monocytes. Cohn, P.D., Emanuel, P.D., Bozdech, M.J. Blood (1987) [Pubmed]
  9. Immunohistochemical localization of membrane and alpha-granule proteins in plastic-embedded mouse bone marrow megakaryocytes and murine megakaryocyte colonies. Stenberg, P.E., Beckstead, J.H., McEver, R.P., Levin, J. Blood (1986) [Pubmed]
  10. Use of surface marker analysis to predict outcome of adult acute myeloblastic leukemia. Griffin, J.D., Davis, R., Nelson, D.A., Davey, F.R., Mayer, R.J., Schiffer, C., McIntyre, O.R., Bloomfield, C.D. Blood (1986) [Pubmed]
  11. Langerhans' cells and macrophages in eosinophilic granuloma. An enzyme-histochemical, enzyme-cytochemical, and ultrastructural study. Elema, J.D., Atmosoerodjo-Briggs, J.E. Cancer (1984) [Pubmed]
  12. Screening and characterization of a novel esterase from a metagenomic library. Kim, Y.J., Choi, G.S., Kim, S.B., Yoon, G.S., Kim, Y.S., Ryu, Y.W. Protein Expr. Purif. (2006) [Pubmed]
  13. Prenatal diagnosis of neural tube defects using the cholinesterases. Simpson, N.E. Isozymes Curr. Top. Biol. Med. Res. (1983) [Pubmed]
  14. Varied differentiation responses of human leukemias to bryostatin 1. Kraft, A.S., William, F., Pettit, G.R., Lilly, M.B. Cancer Res. (1989) [Pubmed]
  15. Combination of a potent 20-epi-vitamin D3 analogue (KH 1060) with 9-cis-retinoic acid irreversibly inhibits clonal growth, decreases bcl-2 expression, and induces apoptosis in HL-60 leukemic cells. Elstner, E., Linker-Israeli, M., Umiel, T., Le, J., Grillier, I., Said, J., Shintaku, I.P., Krajewski, S., Reed, J.C., Binderup, L., Koeffler, H.P. Cancer Res. (1996) [Pubmed]
  16. c-myc and c-myb oncoproteins during induced maturation of myeloid and erythroid human leukemic cell lines. Pedrazzoli, P., Bains, M.A., Watson, R., Fisher, J., Hoy, T.G., Jacobs, A. Cancer Res. (1989) [Pubmed]
  17. T cell leukemia presenting as chronic polyarthritis. van Soesbergen, R.M., Feltkamp-Vroom, T.M., Feltkamp, C.A., Somers, R., van Beek, W.P. Arthritis Rheum. (1982) [Pubmed]
  18. Determination of rat plasma esterase-1 (ES-1) activity by scanning densitometry of gradient polyacrylamide gels with zymogram detection. Van Lith, H.A., Haller, M., Van Zutphen, B.F., Beynen, A.C. Electrophoresis (1991) [Pubmed]
  19. Chromosome pattern in childhood acute nonlymphocytic leukemia (ANLL). Kaneko, Y., Rowley, J.D., Maurer, H.S., Variakojis, D., Moohr, J.W. Blood (1982) [Pubmed]
  20. Hematopoietic factor production by a cell line (TC-1) derived from adherent murine marrow cells. Song, Z.X., Shadduck, R.K., Innes, D.J., Waheed, A., Quesenberry, P.J. Blood (1985) [Pubmed]
  21. Cytochemically demonstrable B-glucuronidase activity in normal and neoplastic human lymphoid cells. Machin, G.A., Halper, J.P., Knowles, D.M. Blood (1980) [Pubmed]
  22. Immunohistochemical localization of membrane and alpha-granule proteins in human megakaryocytes: application to plastic-embedded bone marrow biopsy specimens. Beckstead, J.H., Stenberg, P.E., McEver, R.P., Shuman, M.A., Bainton, D.F. Blood (1986) [Pubmed]
  23. Thymic origin of the prolactin-dependent Nb2 lymphoma cell line. Fleming, W.H., Pettigrew, N.M., Matusik, R.J., Friesen, H.G. Cancer Res. (1982) [Pubmed]
  24. Acute megakaryoblastic leukemia in early childhood. Chan, W.C., Brynes, R.K., Kim, T.H., Verras, A., Schick, C., Green, R.J., Ragab, A.H. Blood (1983) [Pubmed]
  25. Large granular lymphocytes in human peripheral blood: ultrastructural and cytochemical characterization of the granules. Grossi, C.E., Cadoni, A., Zicca, A., Leprini, A., Ferrarini, M. Blood (1982) [Pubmed]
  26. Establishment of a human megakaryoblastic cell line (T-33) from chronic myelogenous leukemia in megakaryoblastic crisis. Tange, T., Nakahara, K., Mitani, K., Yamasaki, I., Yasuda, H., Tanaka, F., Mizuguchi, M., Oda, H., Yatomi, Y., Takanashi, R. Cancer Res. (1988) [Pubmed]
  27. [3H]Indole-3-acetyl-myo-inositol hydrolysis by extracts of Zea mays L. vegetative tissue. Hall, P.J., Bandurski, R.S. Plant Physiol. (1986) [Pubmed]
  28. Induction of differentiation of human myeloid leukemia cells by jasmonates, plant hormones. Ishii, Y., Kiyota, H., Sakai, S., Honma, Y. Leukemia (2004) [Pubmed]
  29. Vitamin D3 analogue KH1060 combined with TPA synergistically induces mature macrophages in human myeloblastic leukemia ML-1 cells. Saito, Y., Hatta, H., Mano, Y., Taira, N., Shimizu, T., Takeda, K. Anticancer Res. (1999) [Pubmed]
  30. Purification and kinetic characterisation of juvenile hormone esterase from Drosophila melanogaster. Campbell, P.M., Oakeshott, J.G., Healy, M.J. Insect Biochem. Mol. Biol. (1998) [Pubmed]
  31. Myeloid enzymes profile related to the immunophenotypic characteristics of blast cells from patients with acute myeloid leukemia (AML) at diagnosis. Klobusicka, M., Kusenda, J., Babusikova, O. Neoplasma (2005) [Pubmed]
  32. Regulation of mouse liver microsomal esterases by clofibrate and sexual hormones. Parker, A.G., Pinot, F., Grant, D.F., Spearow, J., Hammock, B.D. Biochem. Pharmacol. (1996) [Pubmed]
  33. Synergism of tumor necrosis factor and interferon-gamma in induction of differentiation of human myeloblastic leukemic ML-1 cells. Takuma, T., Takeda, K., Konno, K. Biochem. Biophys. Res. Commun. (1987) [Pubmed]
  34. Identification of a frameshift mutation responsible for the silent phenotype of human serum cholinesterase, Gly 117 (GGT----GGAG). Nogueira, C.P., McGuire, M.C., Graeser, C., Bartels, C.F., Arpagaus, M., Van der Spek, A.F., Lightstone, H., Lockridge, O., La Du, B.N. Am. J. Hum. Genet. (1990) [Pubmed]
  35. Rat serum carboxylesterase. Cloning, expression, regulation, and evidence of secretion from liver. Yan, B., Yang, D., Bullock, P., Parkinson, A. J. Biol. Chem. (1995) [Pubmed]
  36. Nonspecific acid esterase activity: a criterion for differentiation of T and B lymphocytes in mouse lymph nodes. Mueller, J., Brun del Re, G., Buerki, H., Keller, H.U., Hess, M.W., Cottier, H. Eur. J. Immunol. (1975) [Pubmed]
  37. Expression of monocytic--histiocytic cytochemical markers in epithelial neoplasia. Tubbs, R.R., Savage, R.A., Crabtree, R.H., Sebek, B.A., Valenzuela, R., Benjamin, S.P. Am. J. Clin. Pathol. (1979) [Pubmed]
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