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Disease relevance of Cichlids


Psychiatry related information on Cichlids


High impact information on Cichlids

  • The East African Great Lakes harbour hundreds of cichlid species representing only a few monophyletic lineages, although palaeolimnological evidence and local restrictions on species distribution suggest that speciation in these lakes could have been allopatric [4].
  • Extensive MHC variability in cichlid fishes of Lake Malawi [5].
  • Species-specific differences in jaw shape are obvious early in cichlid larval development and are correlated with patterns of bmp4 expression in the mandibular primordium [6].
  • Three GnRH receptor types in laser-captured single cells of the cichlid pituitary display cellular and functional heterogeneity [7].
  • The reconstruction of cichlid RH1 pigments with 11-cis-retinal from 28 sequences showed that the absorption spectra of the pigments of nine species were shifted toward blue, tuned by two particular amino acid replacements [8].

Chemical compound and disease context of Cichlids


Biological context of Cichlids


Anatomical context of Cichlids


Associations of Cichlids with chemical compounds


Gene context of Cichlids


Analytical, diagnostic and therapeutic context of Cichlids


  1. Investigation of acute toxicity of chlorpyrifos-methyl on Nile tilapia (Oreochromis niloticus L.) larvae. Gül, A. Chemosphere (2005) [Pubmed]
  2. The cusp of evolution and development: a model of cichlid tooth shape diversity. Streelman, J.T., Webb, J.F., Albertson, R.C., Kocher, T.D. Evol. Dev. (2003) [Pubmed]
  3. Steroid hormones and agonistic behavior in a cichlid teleost, Aequidens pulcher. Munro, A.D., Pitcher, T.J. Hormones and behavior. (1985) [Pubmed]
  4. Sympatric speciation suggested by monophyly of crater lake cichlids. Schliewen, U.K., Tautz, D., Pääbo, S. Nature (1994) [Pubmed]
  5. Extensive MHC variability in cichlid fishes of Lake Malawi. Klein, D., Ono, H., O'hUigin, C., Vincek, V., Goldschmidt, T., Klein, J. Nature (1993) [Pubmed]
  6. Integration and evolution of the cichlid mandible: the molecular basis of alternate feeding strategies. Albertson, R.C., Streelman, J.T., Kocher, T.D., Yelick, P.C. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  7. Three GnRH receptor types in laser-captured single cells of the cichlid pituitary display cellular and functional heterogeneity. Parhar, I.S., Ogawa, S., Sakuma, Y. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  8. Parallelism of amino acid changes at the RH1 affecting spectral sensitivity among deep-water cichlids from Lakes Tanganyika and Malawi. Sugawara, T., Terai, Y., Imai, H., Turner, G.F., Koblmüller, S., Sturmbauer, C., Shichida, Y., Okada, N. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  9. Acute toxicity of deltamethrin and dieldrin to Oreochromis niloticus (LIN). Golow, A.A., Godzi, T.A. Bulletin of environmental contamination and toxicology. (1994) [Pubmed]
  10. Replicated evolution of trophic specializations in an endemic cichlid fish lineage from Lake Tanganyika. Rüber, L., Verheyen, E., Meyer, A. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  11. The complexity of alternative splicing of hagoromo mRNAs is increased in an explosively speciated lineage in East African cichlids. Terai, Y., Morikawa, N., Kawakami, K., Okada, N. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  12. Natural selection of the rhodopsin gene during the adaptive radiation of East African Great Lakes cichlid fishes. Sugawara, T., Terai, Y., Okada, N. Mol. Biol. Evol. (2002) [Pubmed]
  13. Isolation, characterization and expression of 11beta-hydroxysteroid dehydrogenase type 2 cDNAs from the testes of Japanese eel (Anguilla japonica) and Nile tilapia (Oreochromis niloticus). Jiang, J.Q., Wang, D.S., Senthilkumaran, B., Kobayashi, T., Kobayashi, H.K., Yamaguchi, A., Ge, W., Young, G., Nagahama, Y. J. Mol. Endocrinol. (2003) [Pubmed]
  14. Synergistic expression of Ad4BP/SF-1 and cytochrome P-450 aromatase (ovarian type) in the ovary of Nile tilapia, Oreochromis niloticus, during vitellogenesis suggests transcriptional interaction. Yoshiura, Y., Senthilkumaran, B., Watanabe, M., Oba, Y., Kobayashi, T., Nagahama, Y. Biol. Reprod. (2003) [Pubmed]
  15. Genes encoding putative natural killer cell C-type lectin receptors in teleostean fishes. Sato, A., Mayer, W.E., Overath, P., Klein, J. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  16. The goitrogen 6-n-propyl-2-thiouracil (PTU) given during testis development increases Sertoli and germ cell numbers per cyst in fish: the tilapia (Oreochromis niloticus) model. Matta, S.L., Vilela, D.A., Godinho, H.P., França, L.R. Endocrinology (2002) [Pubmed]
  17. Neuropeptide Y in the forebrain of the adult male cichlid fish Oreochromis mossambicus: distribution, effects of castration and testosterone replacement. Sakharkar, A.J., Singru, P.S., Sarkar, K., Subhedar, N.K. J. Comp. Neurol. (2005) [Pubmed]
  18. Different thyroid hormone-deiodinating enzymes in tilapia (Oreochromis niloticus) liver and kidney. Mol, K., Kaptein, E., Darras, V.M., de Greef, W.J., Kühn, E.R., Visser, T.J. FEBS Lett. (1993) [Pubmed]
  19. Nitric oxide synthase in the caudal neurosecretory system of the teleost Oreochromis niloticus. Cioni, C., Greco, A., Pepe, A., De Vito, L., Colasanti, M. Neurosci. Lett. (1997) [Pubmed]
  20. Cortisol rapidly reduces prolactin release and cAMP and 45Ca2+ accumulation in the cichlid fish pituitary in vitro. Borski, R.J., Helms, L.M., Richman, N.H., Grau, E.G. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  21. Thyroid hormone and estrogen regulate brain region-specific messenger ribonucleic acids encoding three gonadotropin-releasing hormone genes in sexually immature male fish, Oreochromis niloticus. Parhar, I.S., Soga, T., Sakuma, Y. Endocrinology (2000) [Pubmed]
  22. Single-cell real-time quantitative polymerase chain reaction of immunofluorescently identified neurons of gonadotropin-releasing hormone subtypes in cichlid fish. Parhar, I.S., Ogawa, S., Hamada, T., Sakuma, Y. Endocrinology (2003) [Pubmed]
  23. Light and circadian modulation of teleost retinal tyrosine hydroxylase activity. McCormack, C.A., Burnside, B. Invest. Ophthalmol. Vis. Sci. (1993) [Pubmed]
  24. Effects of melatonin, serotonin, and naloxone on aggression in isolated cichlid fish (Aequidens pulcher). Munro, A.D. J. Pineal Res. (1986) [Pubmed]
  25. Cloning and characterization of type III iodothyronine deiodinase from the fish Oreochromis niloticus. Sanders, J.P., Van der Geyten, S., Kaptein, E., Darras, V.M., Kühn, E.R., Leonard, J.L., Visser, T.J. Endocrinology (1999) [Pubmed]
  26. The evolution of genes for pigmentation in African cichlid fishes. Sugie, A., Terai, Y., Ota, R., Okada, N. Gene (2004) [Pubmed]
  27. Identification of chemokines and a chemokine receptor in cichlid fish, shark, and lamprey. Kuroda, N., Uinuk-ool, T.S., Sato, A., Samonte, I.E., Figueroa, F., Mayer, W.E., Klein, J. Immunogenetics (2003) [Pubmed]
  28. Differential expression of tuberoinfundibular peptide 38 and glucose-6-phosphatase in tilapia. Shoemaker, J.M., Riley, L.G., Hirano, T., Grau, E.G., Rubin, D.A. Gen. Comp. Endocrinol. (2006) [Pubmed]
  29. Trends in the evolution of the prodynorphin gene in teleosts: cloning of eel and tilapia prodynorphin cDNAs. Alrubaian, J., Lecaude, S., Barba, J., Szynskie, L., Jacobs, N., Bauer, D., Brown, C., Kaminer, I., Bagrosky, B., Dores, R.M. Peptides (2006) [Pubmed]
  30. In situ hybridization for two differentially expressed GnRH genes following estrogen and triiodothyronine treatment in the brains of juvenile tilapia (cichlid). Parhar, I.S., Soga, T., Sakuma, Y. Neurosci. Lett. (1996) [Pubmed]
  31. The effects of oral administration with 17 alpha-methyltestosterone on chromosomal synapsis in Oreochromis niloticus (Pisces, Cichlidae). Carrasco, L.A., Penman, D.J., Villalobos, S.A., Bromage, N. Mutat. Res. (1999) [Pubmed]
  32. Molecular cloning of DAX1 and SHP cDNAs and their expression patterns in the Nile tilapia, Oreochromis niloticus. Wang, D.S., Kobayashi, T., Senthilkumaran, B., Sakai, F., Sudhakumari, C.C., Suzuki, T., Yoshikuni, M., Matsuda, M., Morohashi, K., Nagahama, Y. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  33. A vaccination and challenge model using calcein marked fish. Klesius, P.H., Evans, J.J., Shoemaker, C.A., Pasnik, D.J. Fish Shellfish Immunol. (2006) [Pubmed]
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