Disease relevance of Tilapia

• Weight gain analyzed by broken-line regression indicated that the adequate dietary niacin level for maximal growth in rapidly growing tilapia fingerlings is 26 mg/kg in fish fed the glucose diet and 121 mg/kg in fish fed the dextrin diet [1].
• CONCLUSIONS: Our results suggest that ''glucose toxicity'' plays a role in the immediate demise of intraportal tilapia islet xenografts [2].
• Observations were made on stretched preparations from the swim bladder and peritoneum obtained from tilapia (Oreochromis niloticus) after injection of formalin-killed Escherichia coli, proteose peptone, compound 48/80 or HBSS into the swim bladder [3].
• Atrial tachyarrhythmias induced by acetylcholine in tilapia (Oreochromis sp.) isolated atria [4].
• In the current study, the authors examined the effects of experimentally induced hypothyroidism on peripheral thyroid hormone metabolism and growth in two closely related tilapia species: the Nile tilapia (Oreochromis niloticus) and the slower growing black tilapia (Sarotherodon melanotheron) [5].

Psychiatry related information on Tilapia

• Influence of temperature and gonadal steroids on the ontogenetic expression of brain serotonin 1A and 1D receptors during the critical period of sexual differentiation in tilapia, Oreochromis mossambicus [6].

High impact information on Tilapia

• To address this issue, we developed a technology integrating laser-captured microdissection of single digoxigenin-labeled pituitary cells coupled with real-time quantitative PCR to examine the expression profiles of three endogenous GnRH-R types (R1, R2, and R3) in immature and mature males of tilapia Oreochromis niloticus [7].
• Kidney-specific chloride channel, OmClC-K, predominantly expressed in the diluting segment of freshwater-adapted tilapia kidney [8].
• Tilapia GH (tGH) and tPRL177 stimulated sulfate uptake at the highest doses examined [9].
• By using an expression cloning strategy, we isolated a single positive clone encoding a tilapia prolactin (PRL) receptor [10].
• The tilapia PRL receptor is a mature protein of 606 amino acids [10].

Chemical compound and disease context of Tilapia

• Impact of methyl parathion toxicity and eserine inhibition on acetylcholinesterase activity in tissues of the teleost (Tilapia mossambica)--a correlative study [11].
• Sublethal toxicity of malathion on the proteases and free amino acid composition in the liver of the teleost, Tilapia mossambica (Peters) [12].
• Atrazine toxicity on hydromineral balance of fish, Tilapia mossambicus [13].
• Acute toxicity of monocrotophos (MCP) and its newly synthesized thiol analogs 2-butenoic acid-3-(diethoxyphosphinothionyl) methyl ester (RPR II) and 2-butenoic acid-3-(diethoxyphosphinothionyl) ethyl ester (RPR-V) was studied on euryhaline fish, Oreochromis mossambicus [14].
• Analytical procedures were developed and used for the studies of acute toxicity and bioaccumulation of Diazinon in red tilapia [15].

Biological context of Tilapia

• The GnRH responsive region in tilapia FSHbeta 5' flanking region spans the canonical AP1 and CRE motifs implicating both elements in conferring GnRH responsiveness [16].
• The tilapia GPR54 cDNA contains an open reading frame of 1131 bp encoding 377 amino acids and exhibits 56% identity to human GPR54 [17].
• The deduced amino acid sequence shows 57-67% identity with frog, chicken, and mammalian D3, 33-39% identity with frog, fish (Fundulus heteroclitus) and mammalian D2, and 30-35% identity with fish (tilapia), chicken, and mammalian D1 [18].
• Tilapia liver T4 ORD activity and tilapia brain and gill T3 IRD activities show very similar substrate specificities as well as similar inhibitor sensitivities as rat type II and type III iodothyronine deiodinase, respectively [19].
• A non-radioactive in situ hybridization procedure has allowed us to detect the expression of the tilapia PRL-R in the branchial chloride cells and the intestinal mucosal layer of fresh water animals, confirming the direct control exerted by prolactin on the water and ionic exchanges in tilapia [20].

Anatomical context of Tilapia

• We examined the effects of injecting homologous GH or the two homologous tilapia PRLs (tPRL177 and tPRL188) on the in vitro incorporation of [35S] sulfate (extracellular matrix synthesis) and [3H]thymidine (DNA synthesis) by ceratobranchial cartilage explants and on IGF-I mRNA levels in tilapia liver [9].
• The level of ppMCH mRNA expression in tilapia hypothalamus, measured by dot blot analysis, was significantly higher in fish adapted to a white background than in black-adapted animals, which is in accordance with the reported MCH plasma and tissue concentrations in fish [21].
• On the other hand, nuclei of rooster and tilapia spermatozoa and those of immature hamster and mouse spermatozoa, which are not stabilized by protamine disulfide bonds, were sensitive to heating; although some of them decondensed after exposure to 90 degrees C, none formed male pronuclei [22].
• We also examined functional characteristics of tilapia AQP3 using Xenopus oocytes as an in vitro transcribed cRNA expression system [23].
• Mitochondria-rich cell activity in the yolk-sac membrane of tilapia (Oreochromis mossambicus) larvae acclimatized to different ambient chloride levels [24].

Associations of Tilapia with chemical compounds

• Cortisol (50 nM) also inhibits cAMP accumulation and reduces 45Ca2+ accumulation in the tilapia rostral pars distalis within 15 min [25].
• Muscle as the primary site of urea cycle enzyme activity in an alkaline lake-adapted tilapia, Oreochromis alcalicus grahami [26].
• Possible interactions between gonadotrophs and somatotrophs in the pituitary of tilapia: apparent roles for insulin-like growth factor I and estradiol [27].
• Dopamine causes ultrastructural changes in prolactin cells of tilapia (Oreochromis niloticus) [28].
• METHODS: To test the efficacy of LTAC in a discordant islet xenograft model, tilapia (fish) islets were transplanted under the left kidney capsules of streptozotocin-diabetic Balb/c mice [29].

Gene context of Tilapia

• Immune localization of prolactin receptor in the mitochondria-rich cells of the euryhaline teleost (Oreochromis mossambicus) gill [30].
• TSHR sequence comparisons were sought for an additional eight mammals as well as four (two Salmon, Tilapia, and Sea Bass) from teleosts [31].
• Various degrees of dissociation of NADPHd activity and nNOS immunoreactivity have been detected that could be attributed to the expression of different subtypes of nNOS in the preoptic/hypothalamo/hypophysial system of tilapia [32].
• Except for the 39th residue, both tilapia cDNA sequences showed significant identity to human, bovine, murine, fugu, and zebrafish TIP39 [33].
• Thus, a novel regulatory mechanism of GH secretion by gastric ghrelin seems to be conserved in the tilapia [34].

Analytical, diagnostic and therapeutic context of Tilapia

• Western blotting of conditioned medium from human embryonal kidney (HEK293) cells overexpressing a His-tagged tilapia MSTN indicates that the secreted fish protein is processed in a manner similar to mouse MSTN [35].
• Chloride cells were identified by Na(+)/K(+)-ATPase immunocytochemistry at the light and electron microscope levels in gills of freshwater tilapia Oreochromis mossambicus [36].
• Plasma levels of tilapia GH and prolactins (tPRL(177) and tPRL(188)) were determined by radioimmunoassay [37].
• Tilapia (Oreochromis mossambicus) were given a single intraperitoneal injection of KP-102 (D-Ala-D-beta;-Nal-Ala-Trp-D-Phe-Lys-NH(2)) or bovine GHRH(1-29)-amide or vehicle and blood was sampled at 1, 6 and 12 h after injection [37].
• Three forms of gonadotropin-releasing hormone (GnRH) are isolated and identified here by chemical sequence analysis for one species of tilapia, Oreochromis niloticus, and by HPLC elution position for a second species of tilapia, O. mossambicus [38].

References