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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Graft Rejection

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Disease relevance of Graft Rejection


High impact information on Graft Rejection


Chemical compound and disease context of Graft Rejection


Biological context of Graft Rejection


Anatomical context of Graft Rejection


Associations of Graft Rejection with chemical compounds


Gene context of Graft Rejection

  • Our findings indicate that good HLA-A and B matching is highly dependent on a system for sharing organs among institutions, and results in decreased graft rejection, better long-term graft function, and less need for post-transplantation immunosuppression [31].
  • We used three in vivo models to demonstrate a role for CXCR3 in the development of transplant rejection [32].
  • During acute and chronic transplant rejection, ligands for CCR5 are upregulated, and the graft is infiltrated by CCR5-positive mononuclear cells [33].
  • Recent data implicates a role for the CD40-CD40 ligand (CD40L) pathway in graft rejection [34].
  • For BM graft rejection studies, IL-10 was infused into sublethally irradiated recipients of anti-Thy 1.2 + C' T-cell-depleted, fully allogeneic BM grafts [35].

Analytical, diagnostic and therapeutic context of Graft Rejection


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  2. Neurological complications following liver transplantation. Adams, D.H., Ponsford, S., Gunson, B., Boon, A., Honigsberger, L., Williams, A., Buckels, J., Elias, E., McMaster, P. Lancet (1987) [Pubmed]
  3. Letter: Increased serum creatinine resulting from hyperglycemia, mimicking transplant rejection. Matas, A.J., Simmons, R.L., Goetz, F.C., Kjellstrand, C.M., Najarian, J.S. Ann. Intern. Med. (1975) [Pubmed]
  4. Proteomic method identifies proteins nitrated in vivo during inflammatory challenge. Aulak, K.S., Miyagi, M., Yan, L., West, K.A., Massillon, D., Crabb, J.W., Stuehr, D.J. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  5. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Balashov, K.E., Rottman, J.B., Weiner, H.L., Hancock, W.W. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  6. Murine natural killer cells and marrow graft rejection. Yu, Y.Y., Kumar, V., Bennett, M. Annu. Rev. Immunol. (1992) [Pubmed]
  7. Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. Lowance, D., Neumayer, H.H., Legendre, C.M., Squifflet, J.P., Kovarik, J., Brennan, P.J., Norman, D., Mendez, R., Keating, M.R., Coggon, G.L., Crisp, A., Lee, I.C. N. Engl. J. Med. (1999) [Pubmed]
  8. Long-term efficacy and safety of cyclosporine in renal-transplant recipients. Burke, J.F., Pirsch, J.D., Ramos, E.L., Salomon, D.R., Stablein, D.M., Van Buren, D.H., West, J.C. N. Engl. J. Med. (1994) [Pubmed]
  9. Randomized controlled trial of a monoclonal antibody against the interleukin-2 receptor (33B3.1) as compared with rabbit antithymocyte globulin for prophylaxis against rejection of renal allografts. Soulillou, J.P., Cantarovich, D., Le Mauff, B., Giral, M., Robillard, N., Hourmant, M., Hirn, M., Jacques, Y. N. Engl. J. Med. (1990) [Pubmed]
  10. Prevention of acute graft rejection by the prostaglandin E1 analogue misoprostol in renal-transplant recipients treated with cyclosporine and prednisone. Moran, M., Mozes, M.F., Maddux, M.S., Veremis, S., Bartkus, C., Ketel, B., Pollak, R., Wallemark, C., Jonasson, O. N. Engl. J. Med. (1990) [Pubmed]
  11. Autografting followed by nonmyeloablative immunosuppressive chemotherapy and allogeneic peripheral-blood hematopoietic stem-cell transplantation as treatment of resistant Hodgkin's disease and non-Hodgkin's lymphoma. Carella, A.M., Cavaliere, M., Lerma, E., Ferrara, R., Tedeschi, L., Romanelli, A., Vinci, M., Pinotti, G., Lambelet, P., Loni, C., Verdiani, S., De Stefano, F., Valbonesi, M., Corsetti, M.T. J. Clin. Oncol. (2000) [Pubmed]
  12. Nicardipine as antihypertensive therapy in liver transplant recipients: results of long-term use. Duvoux, C., Cherqui, D., Di Martino, V., Métreau, J.M., Salvat, A., Lauzet, J.Y., Fagniez, P.L., Dhumeaux, D. Hepatology (1997) [Pubmed]
  13. Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression. Manna, S.K., Aggarwal, B.B. J. Immunol. (1999) [Pubmed]
  14. Adenosine deaminase: functional implications and different classes of inhibitors. Cristalli, G., Costanzi, S., Lambertucci, C., Lupidi, G., Vittori, S., Volpini, R., Camaioni, E. Medicinal research reviews. (2001) [Pubmed]
  15. Indium-111 antimyosin scintigraphy to assess myocardial damage in patients with suspected myocarditis and cardiac rejection. Carrió, I., Berná, L., Ballester, M., Estorch, M., Obrador, D., Cladellas, M., Abadal, L., Ginjaume, M. J. Nucl. Med. (1988) [Pubmed]
  16. A physical map of the human Y chromosome. Tilford, C.A., Kuroda-Kawaguchi, T., Skaletsky, H., Rozen, S., Brown, L.G., Rosenberg, M., McPherson, J.D., Wylie, K., Sekhon, M., Kucaba, T.A., Waterston, R.H., Page, D.C. Nature (2001) [Pubmed]
  17. Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex. Mendoza, L.M., Paz, P., Zuberi, A., Christianson, G., Roopenian, D., Shastri, N. Immunity (1997) [Pubmed]
  18. Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejection. Ohdan, H., Yang, Y.G., Shimizu, A., Swenson, K.G., Sykes, M. J. Clin. Invest. (1999) [Pubmed]
  19. Granzyme B: pro-apoptotic, antiviral and antitumor functions. Trapani, J.A., Sutton, V.R. Curr. Opin. Immunol. (2003) [Pubmed]
  20. Mechanism of action of glatiramer acetate in multiple sclerosis and its potential for the development of new applications. Arnon, R., Aharoni, R. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  21. Murine cells expressing an HLA molecule are specifically lysed by HLA-restricted antiviral human T cells. Gomard, E., Begue, B., Sodoyer, S., Maryanski, J.L., Jordan, B.R., Levy, J.P. Nature (1986) [Pubmed]
  22. Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection. Yolcu, E.S., Askenasy, N., Singh, N.P., Cherradi, S.E., Shirwan, H. Immunity (2002) [Pubmed]
  23. Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy. Gao, E.K., Lo, D., Sprent, J. J. Exp. Med. (1990) [Pubmed]
  24. Is azathioprine necessary in renal transplantation? Sheriff, M.H., Yayha, T., Lee, H.A. Lancet (1978) [Pubmed]
  25. Coronary artery disease in cardiac transplant patients receiving triple-drug immunosuppressive therapy. Olivari, M.T., Homans, D.C., Wilson, R.F., Kubo, S.H., Ring, W.S. Circulation (1989) [Pubmed]
  26. Local synthesis of complement component C3 regulates acute renal transplant rejection. Pratt, J.R., Basheer, S.A., Sacks, S.H. Nat. Med. (2002) [Pubmed]
  27. Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury. Otterbein, L.E., Zuckerbraun, B.S., Haga, M., Liu, F., Song, R., Usheva, A., Stachulak, C., Bodyak, N., Smith, R.N., Csizmadia, E., Tyagi, S., Akamatsu, Y., Flavell, R.J., Billiar, T.R., Tzeng, E., Bach, F.H., Choi, A.M., Soares, M.P. Nat. Med. (2003) [Pubmed]
  28. Long-term skin allograft survival after short-term cyclosporin treatment in a patient with massive burns. Achauer, B.M., Hewitt, C.W., Black, K.S., Martinez, S.E., Waxman, K.S., Ott, R.A., Furnas, D.W. Lancet (1986) [Pubmed]
  29. Mycophenolate mofetil to rescue children with acute renal transplant rejection. Birkeland, S.A. Lancet (1996) [Pubmed]
  30. Deoxyspergualin for liver graft rejection. Groth, C.G., Ohlman, S., Ericzon, B.G., Barkholt, L., Reinholt, F.P. Lancet (1990) [Pubmed]
  31. Benefits of HLA-A and HLA-B matching on graft and patient outcome after cadaveric-donor renal transplantation. Sanfilippo, F., Vaughn, W.K., Spees, E.K., Light, J.A., LeFor, W.M. N. Engl. J. Med. (1984) [Pubmed]
  32. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. Hancock, W.W., Lu, B., Gao, W., Csizmadia, V., Faia, K., King, J.A., Smiley, S.T., Ling, M., Gerard, N.P., Gerard, C. J. Exp. Med. (2000) [Pubmed]
  33. CC chemokine receptor 5 and renal-transplant survival. Fischereder, M., Luckow, B., Hocher, B., Wüthrich, R.P., Rothenpieler, U., Schneeberger, H., Panzer, U., Stahl, R.A., Hauser, I.A., Budde, K., Neumayer, H., Krämer, B.K., Land, W., Schlöndorff, D. Lancet (2001) [Pubmed]
  34. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Hancock, W.W., Sayegh, M.H., Zheng, X.G., Peach, R., Linsley, P.S., Turka, L.A. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  35. Interleukin-10 administration decreases survival in murine recipients of major histocompatibility complex disparate donor bone marrow grafts. Blazar, B.R., Taylor, P.A., Smith, S., Vallera, D.A. Blood (1995) [Pubmed]
  36. Early detection of rejection and assessment of cyclosporine therapy by 111In antimyosin imaging in mouse heart allografts. Isobe, M., Haber, E., Khaw, B.A. Circulation (1991) [Pubmed]
  37. Heart transplant rejection monitored by signal-averaged electrocardiography in patients receiving cyclosporine. Keren, A., Gillis, A.M., Freedman, R.A., Baldwin, J.C., Billingham, M.E., Stinson, E.B., Simson, M.B., Mason, J.W. Circulation (1984) [Pubmed]
  38. Myeloid and lymphoid chimerism after T-cell-depleted bone marrow transplantation: evaluation of conditioning regimens using the polymerase chain reaction to amplify human minisatellite regions of genomic DNA. Mackinnon, S., Barnett, L., Bourhis, J.H., Black, P., Heller, G., O'Reilly, R.J. Blood (1992) [Pubmed]
  39. Morphologic features of spleen allografts in rats. Graft rejection, acceptance, or lethal graft-versus-host disease in the same donor-recipient pairing. Bitter-Suermann, H., Herbertson, B.M. Am. J. Pathol. (1975) [Pubmed]
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