Chemical Compound Review:
Leukotriene C (5S,6R,7E,9E,11Z,14Z)-6-[2- [(4-amino-4...
Synonyms:
leukotriene C4, LTC4, BML1-E07, LS-72363, LTC (sub 4), ...
- Bronchoconstrictor effects of leukotriene C in humans. Weiss, J.W., Drazen, J.M., Coles, N., McFadden, E.R., Weller, P.F., Corey, E.J., Lewis, R.A., Austen, K.F. Science (1982)
- Prevention of endogenous leukotriene production during anaphylaxis in the guinea pig by an inhibitor of leukotriene biosynthesis (MK-886) but not by dexamethasone. Guhlmann, A., Keppler, A., Kästner, S., Krieter, H., Brückner, U.B., Messmer, K., Keppler, D. J. Exp. Med. (1989)
- Interleukin 3-dependent mediator release in basophils triggered by C5a. Kurimoto, Y., de Weck, A.L., Dahinden, C.A. J. Exp. Med. (1989)
- The importance of leukotrienes in airway inflammation in a mouse model of asthma. Henderson, W.R., Lewis, D.B., Albert, R.K., Zhang, Y., Lamm, W.J., Chiang, G.K., Jones, F., Eriksen, P., Tien, Y.T., Jonas, M., Chi, E.Y. J. Exp. Med. (1996)
- Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophages. Neill, M.A., Henderson, W.R., Klebanoff, S.J. J. Exp. Med. (1985)
- Behavioral and physiological effects of leukotriene C4. Landauer, M.R., Davis, H.D., Walden, T.L. Prostaglandins Leukot. Essent. Fatty Acids (1990)
- Characterization of the human cysteinyl leukotriene CysLT1 receptor. Lynch, K.R., O'Neill, G.P., Liu, Q., Im, D.S., Sawyer, N., Metters, K.M., Coulombe, N., Abramovitz, M., Figueroa, D.J., Zeng, Z., Connolly, B.M., Bai, C., Austin, C.P., Chateauneuf, A., Stocco, R., Greig, G.M., Kargman, S., Hooks, S.B., Hosfield, E., Williams, D.L., Ford-Hutchinson, A.W., Caskey, C.T., Evans, J.F. Nature (1999)
- The immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase. Murakami, M., Austen, K.F., Arm, J.P. J. Exp. Med. (1995)
- Toxoplasma gondii alters eicosanoid release by human mononuclear phagocytes: role of leukotrienes in interferon gamma-induced antitoxoplasma activity. Yong, E.C., Chi, E.Y., Henderson, W.R. J. Exp. Med. (1994)
- Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils. Fiore, S., Serhan, C.N. J. Exp. Med. (1990)
- Leukotrienes in the pathophysiology of kwashiorkor. Mayatepek, E., Becker, K., Gana, L., Hoffmann, G.F., Leichsenring, M. Lancet (1993)
- Leukotriene C4 binding to rat lung membranes. Pong, S.S., DeHaven, R.N., Kuehl, F.A., Egan, R.W. J. Biol. Chem. (1983)
- Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. Loe, D.W., Almquist, K.C., Deeley, R.G., Cole, S.P. J. Biol. Chem. (1996)
- Molecular cloning of the gene for human leukotriene C4 synthase. Organization, nucleotide sequence, and chromosomal localization to 5q35. Penrose, J.F., Spector, J., Baldasaro, M., Xu, K., Boyce, J., Arm, J.P., Austen, K.F., Lam, B.K. J. Biol. Chem. (1996)
- In vitro release of prostaglandins and leukotrienes from synovial tissue, cartilage, and bone in degenerative joint diseases. Wittenberg, R.H., Willburger, R.E., Kleemeyer, K.S., Peskar, B.A. Arthritis Rheum. (1993)
- Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor. Hsueh, W., Gonzalez-Crussi, F., Arroyave, J.L. J. Clin. Invest. (1986)
- Leukotriene C4 binds to human glomerular epithelial cells and promotes their proliferation in vitro. Baud, L., Sraer, J., Perez, J., Nivez, M.P., Ardaillou, R. J. Clin. Invest. (1985)
- Interleukin 4 suppresses c-kit ligand-induced expression of cytosolic phospholipase A2 and prostaglandin endoperoxide synthase 2 and their roles in separate pathways of eicosanoid synthesis in mouse bone marrow-derived mast cells. Murakami, M., Penrose, J.F., Urade, Y., Austen, K.F., Arm, J.P. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Subcellular distribution of leukotriene C4 binding units in cultured bovine aortic endothelial cells. Chau, L.Y., Hoover, R.L., Austen, K.F., Lewis, R.A. J. Immunol. (1986)
- The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils. Lam, B.K., Owen, W.F., Austen, K.F., Soberman, R.J. J. Biol. Chem. (1989)
- Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts. Owen, W.F., Rothenberg, M.E., Silberstein, D.S., Gasson, J.C., Stevens, R.L., Austen, K.F., Soberman, R.J. J. Exp. Med. (1987)
- IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, beta-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cells. Razin, E., Mencia-Huerta, J.M., Stevens, R.L., Lewis, R.A., Liu, F.T., Corey, E., Austen, K.F. J. Exp. Med. (1983)
- Dynamics of leukotriene C production by macrophages. Rouzer, C.A., Scott, W.A., Hamill, A.L., Cohn, Z.A. J. Exp. Med. (1980)
- Synthesis of leukotriene C and other arachidonic acid metabolites by mouse pulmonary macrophages. Rouzer, C.A., Scott, W.A., Hamill, A.L., Cohn, Z.A. J. Exp. Med. (1982)
- IgE-independent interleukin-4 expression and induction of a late phase of leukotriene C4 formation in human blood basophils. Ochensberger, B., Rihs, S., Brunner, T., Dahinden, C.A. Blood (1995)
- Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog. Leslie, E.M., Ito , K., Upadhyaya, P., Hecht, S.S., Deeley, R.G., Cole, S.P. J. Biol. Chem. (2001)
- Production of leukotriene C4 in different human tissues is attributable to distinct membrane bound biosynthetic enzymes. Scoggan, K.A., Jakobsson, P.J., Ford-Hutchinson, A.W. J. Biol. Chem. (1997)
- Platelet-activating factor induces mediator release by human basophils primed with IL-3, granulocyte-macrophage colony-stimulating factor, or IL-5. Brunner, T., de Weck, A.L., Dahinden, C.A. J. Immunol. (1991)
- Leukotriene C4 secretion from normal murine mast cells by a probenecid-sensitive and multidrug resistance-associated protein-independent mechanism. Nguyen, T., Gupta, S. J. Immunol. (1997)
- Peptide leukotriene release after antigen challenge in patients sensitive to ragweed. Creticos, P.S., Peters, S.P., Adkinson, N.F., Naclerio, R.M., Hayes, E.C., Norman, P.S., Lichtenstein, L.M. N. Engl. J. Med. (1984)
- Accumulation of leukotriene C4 and histamine in human allergic skin reactions. Talbot, S.F., Atkins, P.C., Goetzl, E.J., Zweiman, B. J. Clin. Invest. (1985)
- Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. Cowburn, A.S., Sladek, K., Soja, J., Adamek, L., Nizankowska, E., Szczeklik, A., Lam, B.K., Penrose, J.F., Austen, F.K., Holgate, S.T., Sampson, A.P. J. Clin. Invest. (1998)
- Isolation and characterization of leukotriene C4 synthetase of rat basophilic leukemia cells. Yoshimoto, T., Soberman, R.J., Lewis, R.A., Austen, K.F. Proc. Natl. Acad. Sci. U.S.A. (1985)