Disease relevance of Hyperbaric Oxygenation

• The aim of this research was to compare the protective effects of mesna, hyperbaric oxygenation (HBO), and their combination in cyclophosphamide-induced hemorrhagic cystitis in guinea pigs [1].
• Early hyperbaric oxygenation treatment improved neurologic deficits and reduced infarct volume, while these effects were reversed by the administration of 5-hydroxydecanoate [2].
• Isobutyl-nitrite-induced methemoglobinemia; treatment with an exchange blood transfusion during hyperbaric oxygenation [3].
• In extreme intracranial hypertension (above 100 mmHg) when there was reactivity to CO2 and the electroencephalogram was flat, rapid balloon deflation was followed by a further gradual increase of intracranial pressure and hyperbaric oxygenation did not restore the cerebrovascular tone [4].
• With the exception of hematological malignancies, hyperbaric oxygenation of in vitro BrdU labeling did not significantly increase BrdU LI or depth of BrdU penetration into tissue [5].

High impact information on Hyperbaric Oxygenation

• Brain gamma-aminobutyric acid, glutamic acid decarboxylase, glutamate, and ammonia in mice during hyperbaric oxygenation [6].
• 3. On hyperbaric oxygenation at 4 X 10(5)Pa, H2O2 production, estimated from the turnover of the catalase reaction, was increased slightly in the liver, and glutathione release was increased slightly, in both lung and liver [7].
• 4. Tocopherol deficiency caused a marked increase in lipid-peroxide formation as indicated by a corresponding increase in glutathione release under hyperbaric oxygenation, with a further enhancement when the tocopherol-deficient rats were also starved [7].
• The effect of hyperbaric oxygenation on the levels of 5-hydroxytryptamine, noradrenaline, dopamine and free amino acids in whole mouse brain [8].
• The effect of hyperbaric oxygenation on arginine metabolism was investigated [9].

Biological context of Hyperbaric Oxygenation

• CONCLUSIONS: Hyperbaric oxygenation in healthy volunteers can induce not only lipid peroxidation, but also liberation of compounds such as TNFa and endothelins, no matter whether pure oxygen is breathed or not [10].

Anatomical context of Hyperbaric Oxygenation

• Treating five of these fetuses with 3.2 +/- 0.4 mg/kg of indomethacin during hyperbaric oxygenation did not alter these effects (PO2 = 51 +/- 8 torr, pulmonary blood flow = 283 +/- 13 ml/kg/min, and pulmonary arterial pressure = 48 +/- 2 torr) [11].
• Sciatic nerve adenosine triphosphate (ATP), creatine phosphate, lactate, and glucose concentrations showed similar changes at rest in both room air and after hyperbaric oxygenation [12].
• We describe the results of early hyperbaric oxygenation combined with nifedipine treatment for central retinal artery occlusion, and explain the results pathophysiologically [13].
• OBJECTIVE: To investigate the response of subcutaneous tissue oxygen (O2) and carbon dioxide (CO2) tensions to hyperbaric oxygenation [14].
• The effects of hyperbaric oxygenation (HBO) and hyperbaric air (HBA) on the cytostatic activity, peroxynitrite synthesis and transcription of the inducible nitric oxide synthetase (iNOS) gene of murine peritoneal macrophages were studied in vitro [15].

Associations of Hyperbaric Oxygenation with chemical compounds

• Management of carbon monoxide poisoning in the absence of hyperbaric oxygenation chamber [16].
• Effect of pentobarbital anesthesia on regional cerebral metabolic rate for glucose during hyperbaric oxygenation in rat [17].
• Two series of experiments were conducted to ascertain whether hyperbaric oxygenation (HBO) treatment with or without antineoplastic chemotherapy can really suppress tumor development in N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN)-induced bladder tumor in rats [18].
• When CO2 failed to influence the intracranial pressure of about 100 mmHg hyperbaric oxygenation did not aid the recovery of the reactivity of the cerebral vessels to CO2 or the vasoconstrictor tone [4].
• Furthermore, early hyperbaric oxygenation significantly decreased the number of apoptotic cells in the peri-infarct cortex 24 h after ischemic insult and this effect was also blocked by 5-hydroxydecanoate [2].

Gene context of Hyperbaric Oxygenation

• The induction of heat shock proteins (HSP72 and HSP27) became weaker in the gerbils with hyperbaric oxygenation than in those without hyperbaric oxygenation, as seen immunohistochemically [19].
• Moreover, more neurons were preserved in the CA1 treated with hyperbaric oxygenation within 6 h of the ischaemia, than when the hyperbaric oxygenation was started 24 h after the ischaemia [19].
• Continuous monitoring of dynamic changes of transcranial regional cerebral oxygenation (rSO2) was performed in 7 healthy volunteers (mean age 40.9 +/- 12.6 years; range 25-62 years) during normo- and hyperbaric oxygenation (HBO at 2.5 and at 1.95 ATA) using an INVOS 3100 cerebral oximeter [20].
• The influence of hyperbaric oxygenation on rat testes [21].
• The vasodilatory effect of superoxide dismutase in hyperbaric oxygenation was not seen in animals given prior doses of the NO synthase inhibitor [22].

Analytical, diagnostic and therapeutic context of Hyperbaric Oxygenation

• Hemodilution, cerebral O2 delivery, and cerebral blood flow: a study using hyperbaric oxygenation [23].
• We evaluated the accuracy of delivery of one type of infusion pump at three nominal flow rates under two environmental pressures (measured in atmospheres absolute, ATA), one of which is used for hyperbaric oxygenation [24].

References