The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Pleurisy


High impact information on Pleurisy


Chemical compound and disease context of Pleurisy

  • The only clinical manifestations that were more common among anti-ENA+ SLE patients were pleuritis and the use of hydroxychloroquine [11].
  • RESULTS: Symptoms were more prolonged and pleural fluid glucose and lactate dehydrogenase concentrations were more markedly abnormal in patients with reactivation pleuritis than in those with classic pleuritis, suggesting a more chronic inflammatory process in the former group [12].
  • Single-chain urokinase alone or complexed to its receptor in tetracycline-induced pleuritis in rabbits [13].
  • ER and AR were never expressed by SFT or by chronic pleuritis, whereas PR were demonstrated in 2/16 "large" (>8 cm) and in 6/16 "small" (< or =8 cm) pleural SFT (all expressing CD34, bcl-2 and CD99) [14].
  • Lactic acid levels in pleural fluid from patients with bacterial pleuritis [15].

Anatomical context of Pleurisy

  • A detailed histological examination of these uPA-deficient animals also revealed a variety of previously unreported phenotypic abnormalities such as pleuritis and the effacement of lymphoid follicles in the regional lymph nodes and spleen [10].
  • T cell proliferation to human parvovirus B19 antigen was measured in 6 patients with recent B19 infection (1 with pneumonia and pleuritis), 1 patient with symptoms persisting >180 days after onset, 18 nonsymptomatic subjects with remote B19 immunity, and 12 B19-seronegative control subjects [16].
  • In each model of pleurisies, ketoprofen and indomethacin reduced the volume of exudate and leukocyte count in a dose-dependent manner but ketoprofen was more active than indomethacin [17].
  • Although ethanol spilling into the thoracic cavity induced effusion and pleuritis, these reactions were manageable [18].
  • The data suggest that local elaboration of interleukin-8 and growth-related protein, in part of mesothelial origin, may influence neutrophil recruitment in tetracycline-induced pleuritis [19].

Gene context of Pleurisy

  • Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10 [20].
  • Real-time RT-PCR assays revealed that the mRNA levels for IFNgamma, TNFalpha, and IL-8 rose over the first few days of TB pleuritis and then declined over the 9 days of the study [21].
  • We assessed the association of vascular endothelial growth factor (VEGF) on the formation of carcinomatosa pleuritis in orthotopic model systems [22].
  • Increased levels of TNF-alpha in plasma of contacts and to some extent pleural fluid of pleuritis patients, is perhaps to limit the infection, while elevated IL-10 in plasma of TB patients and contacts and pleural fluid would perhaps modulate excess proinflammation [23].
  • Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis [24].

Analytical, diagnostic and therapeutic context of Pleurisy


  1. Interleukin 12 at the site of disease in tuberculosis. Zhang, M., Gately, M.K., Wang, E., Gong, J., Wolf, S.F., Lu, S., Modlin, R.L., Barnes, P.F. J. Clin. Invest. (1994) [Pubmed]
  2. Detection and quantification of anti-Ki antibodies by enzyme-linked immunosorbent assay using recombinant Ki antigen. Yamanaka, K., Takasaki, Y., Nishida, Y., Shimada, K., Shibata, M., Hashimoto, H. Arthritis Rheum. (1992) [Pubmed]
  3. Pulmonary involvement in childhood-onset systemic lupus erythematosus: a report of five cases. Ciftçi, E., Yalçinkaya, F., Ince, E., Ekim, M., Ileri, M., Orgerin, Z., Fitöz, S., Güriz, H., Aysev, A.D., Dogru, U. Rheumatology (Oxford, England) (2004) [Pubmed]
  4. Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis. Beyeler, C., Armstrong, M., Bird, H.A., Idle, J.R., Daly, A.K. Ann. Rheum. Dis. (1996) [Pubmed]
  5. Regional mapping of the gene for familial Mediterranean fever on human chromosome 16p13. Fischel-Ghodsian, N., Bu, X., Prezant, T.R., Oeztas, S., Huang, Z.S., Bohlman, M.C., Rotter, J.I., Shohat, M. Am. J. Med. Genet. (1993) [Pubmed]
  6. Thrombophlebitis in systemic lupus erythematosus. Peck, B., Hoffman, G.S., Franck, W.A. JAMA (1978) [Pubmed]
  7. 15-epi-lipoxin A4-mediated induction of nitric oxide explains how aspirin inhibits acute inflammation. Paul-Clark, M.J., Van Cao, T., Moradi-Bidhendi, N., Cooper, D., Gilroy, D.W. J. Exp. Med. (2004) [Pubmed]
  8. Transpleural gradient of 1,25-dihydroxyvitamin D in tuberculous pleuritis. Barnes, P.F., Modlin, R.L., Bikle, D.D., Adams, J.S. J. Clin. Invest. (1989) [Pubmed]
  9. Anti-[(H2A/2B)-DNA]] IgG supports the diagnosis of procainamide-induced arthritis or pleuritis. Lau, C.C., Clos, T.D. Arthritis Rheum. (1999) [Pubmed]
  10. Urokinase-type plasminogen activator-deficient mice are predisposed to staphylococcal botryomycosis, pleuritis, and effacement of lymphoid follicles. Shapiro, R.L., Duquette, J.G., Nunes, I., Roses, D.F., Harris, M.N., Wilson, E.L., Rifkin, D.B. Am. J. Pathol. (1997) [Pubmed]
  11. Utility of anti-Sm, anti-RNP, anti-Ro/SS-A, and anti-La/SS-B (extractable nuclear antigens) detected by enzyme-linked immunosorbent assay for the diagnosis of systemic lupus erythematosus. Sánchez-Guerrero, J., Lew, R.A., Fossel, A.H., Schur, P.H. Arthritis Rheum. (1996) [Pubmed]
  12. Pleuritis as a manifestation of reactivation tuberculosis. Antoniskis, D., Amin, K., Barnes, P.F. Am. J. Med. (1990) [Pubmed]
  13. Single-chain urokinase alone or complexed to its receptor in tetracycline-induced pleuritis in rabbits. Idell, S., Mazar, A., Cines, D., Kuo, A., Parry, G., Gawlak, S., Juarez, J., Koenig, K., Azghani, A., Hadden, W., McLarty, J., Miller, E. Am. J. Respir. Crit. Care Med. (2002) [Pubmed]
  14. Steroid hormone receptor in pleural solitary fibrous tumours and CD34+ progenitor stromal cells. Bongiovanni, M., Viberti, L., Pecchioni, C., Papotti, M., Thonhofer, R., Hans Popper, H., Sapino, A. J. Pathol. (2002) [Pubmed]
  15. Lactic acid levels in pleural fluid from patients with bacterial pleuritis. Riley, T.V. J. Clin. Microbiol. (1985) [Pubmed]
  16. T helper cell-mediated in vitro responses of recently and remotely infected subjects to a candidate recombinant vaccine for human parvovirus b19. Franssila, R., Hokynar, K., Hedman, K. J. Infect. Dis. (2001) [Pubmed]
  17. Effects of ketoprofen and indomethacin on leukocyte migration in two models of pleurisy induced by carrageenan or zymosan-activated serum in rats. Vannier, E., Roch-Arveiller, M., Molinie, B., Terlain, B., Giroud, J.P. J. Pharmacol. Exp. Ther. (1989) [Pubmed]
  18. Preliminary study of percutaneous alcohol injection into the lung. Suzuki, K., Moriyama, N., Yokose, T., Nakaya, Y., Ishihara, T., Niho, S., Nagai, K., Esumi, H. Jpn. J. Cancer Res. (1998) [Pubmed]
  19. Chemokine involvement in tetracycline-induced pleuritis. Miller, E.J., Kajikawa, O., Pueblitz, S., Light, R.W., Koenig, K.K., Idell, S. Eur. Respir. J. (1999) [Pubmed]
  20. Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10. Fine, J.S., Rojas-Triana, A., Jackson, J.V., Engstrom, L.W., Deno, G.S., Lundell, D.J., Bober, L.A. Inflammation (2003) [Pubmed]
  21. Vaccine-induced cytokine responses in a guinea pig model of pulmonary tuberculosis. McMurray, D.N., Allen, S.S., Jeevan, A., Lasco, T., Cho, H., Skwor, T., Yamamoto, T., McFarland, C., Yoshimura, T. Tuberculosis (Edinburgh, Scotland) (2005) [Pubmed]
  22. Biological characteristics of carcinomatosa pleuritis in orthotopic model systems using immune-deficient rats. Ohta, Y., Kimura, K., Tamura, M., Oda, M., Tanaka, M., Sasaki, T., Watanabe, G. Int. J. Oncol. (2001) [Pubmed]
  23. Circulating TNF-alpha, TGF-beta, and IL-10 in tuberculosis patients and healthy contacts. Olobo, J.O., Geletu, M., Demissie, A., Eguale, T., Hiwot, K., Aderaye, G., Britton, S. Scand. J. Immunol. (2001) [Pubmed]
  24. Local production of tumor necrosis factor and IFN-gamma in tuberculous pleuritis. Barnes, P.F., Fong, S.J., Brennan, P.J., Twomey, P.E., Mazumder, A., Modlin, R.L. J. Immunol. (1990) [Pubmed]
  25. A prematurely terminated phase III trial of intraoperative intrapleural hypotonic cisplatin treatment in patients with resected non-small cell lung cancer with positive pleural lavage cytology: the incidence of carcinomatous pleuritis after surgical intervention. Ichinose, Y., Tsuchiya, R., Koike, T., Yasumitsu, T., Nakamura, K., Tada, H., Yoshimura, H., Mitsudomi, T., Nakagawa, K., Yokoi, K., Kato, H. J. Thorac. Cardiovasc. Surg. (2002) [Pubmed]
  26. Hypotonic cisplatin treatment for carcinomatous pleuritis found at thoracotomy in patients with lung cancer. In vitro experiments and preliminary clinical results. Ichinose, Y., Hara, N., Ohta, M., Asoh, H., Yano, T., Maeda, K., Yagawa, K. J. Thorac. Cardiovasc. Surg. (1993) [Pubmed]
  27. Trichomonas tenax empyema in an immunocompromised patient with advanced cancer. Shiota, T., Arizono, N., Morimoto, T., Shimatsu, A., Nakao, K. Parasite (1998) [Pubmed]
  28. Tuberculous pericarditis: importance of adenosine deaminase activity in pericardial fluid. Inoue, T., Iga, K., Hori, K., Matsumura, T., Gen, H., Kijima, K., Kohri, Y., Iwata, T. Intern. Med. (1993) [Pubmed]
WikiGenes - Universities