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Chemical Compound Review

NSC-521040     [3,4-dihydroxy-5-(hydroxy- phosphonooxy...

Synonyms: AC1L1ALE, NSC521040, AR-1C4968, AC1Q6SL9
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Disease relevance of phosphoribosylpyrophosphate


High impact information on phosphoribosylpyrophosphate


Chemical compound and disease context of phosphoribosylpyrophosphate


Biological context of phosphoribosylpyrophosphate


Anatomical context of phosphoribosylpyrophosphate


Associations of phosphoribosylpyrophosphate with other chemical compounds


Gene context of phosphoribosylpyrophosphate


Analytical, diagnostic and therapeutic context of phosphoribosylpyrophosphate


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  30. PRS1 is a key member of the gene family encoding phosphoribosylpyrophosphate synthetase in Saccharomyces cerevisiae. Carter, A.T., Beiche, F., Hove-Jensen, B., Narbad, A., Barker, P.J., Schweizer, L.M., Schweizer, M. Mol. Gen. Genet. (1997) [Pubmed]
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  32. The yeast PRS3 gene is required for cell integrity, cell cycle arrest upon nutrient deprivation, ion homeostasis and the proper organization of the actin cytoskeleton. Binley, K.M., Radcliffe, P.A., Trevethick, J., Duffy, K.A., Sudbery, P.E. Yeast (1999) [Pubmed]
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  36. The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate. Lee, C.E., Goodfellow, C., Javid-Majd, F., Baker, E.N., Shaun Lott, J. J. Mol. Biol. (2006) [Pubmed]
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