Chemical Compound Review:
Methotrexate, (DL)-Isomer 2-[[4-[(2,4-diaminopteridin- 6-yl)methyl...
Synonyms:
Prestwick_753, SureCN3712, AGN-PC-0CK8VG, TCMDC-123832, BSPBio_000210, ...
Strik,
Spreer,
Nagel,
Jacob,
Jung,
Kitze,
Bähr,
Efferth,
Miyachi,
Drexler,
Gebhart,
Yung,
Erdlenbruch,
Alipour,
Fricker,
Miller,
Kugler,
Eibl,
Lakomek,
Reni,
Zaja,
Mason,
Perry,
Mazza,
Spina,
Bordonaro,
Ilariucci,
Faedi,
Corazzelli,
Manno,
Franceschi,
Pace,
Candela,
Abbadessa,
Stelitano,
Latte,
Ferreri,
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- Temozolomide as salvage treatment in primary brain lymphomas. Reni, M., Zaja, F., Mason, W., Perry, J., Mazza, E., Spina, M., Bordonaro, R., Ilariucci, F., Faedi, M., Corazzelli, G., Manno, P., Franceschi, E., Pace, A., Candela, M., Abbadessa, A., Stelitano, C., Latte, G., Ferreri, A.J. Br. J. Cancer (2007)
- Antifolate analogs: mechanism of action, analytical methodology, and clinical efficacy. Fleisher, M. Therapeutic drug monitoring. (1993)
- Cisplatin (CDDP) specifically induces apoptosis via sequential activation of caspase-8, -3 and -6 in osteosarcoma. Seki, K., Yoshikawa, H., Shiiki, K., Hamada, Y., Akamatsu, N., Tasaka, K. Cancer Chemother. Pharmacol. (2000)
- Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. van Halm, V.P., Nurmohamed, M.T., Twisk, J.W., Dijkmans, B.A., Voskuyl, A.E. Arthritis Res. Ther. (2006)
- Variable content of double minute chromosomes is not correlated with degree of phenotype instability in methotrexate-resistant human cell lines. Masters, J., Keeley, B., Gay, H., Attardi, G. Mol. Cell. Biol. (1982)
- Gene deletion chemoselectivity: codeletion of the genes for p16(INK4), methylthioadenosine phosphorylase, and the alpha- and beta-interferons in human pancreatic cell carcinoma lines and its implications for chemotherapy. Chen, Z.H., Zhang, H., Savarese, T.M. Cancer Res. (1996)
- Formation of 7-hydroxymethotrexate polyglutamyl derivatives and their cytotoxicity in human chronic myelogenous leukemia cells, in vitro. Fabre, G., Goldman, I.D. Cancer Res. (1985)
- 7-Hydroxymethotrexate concentrations in serum and cerebrospinal fluid of children with acute lymphoblastic leukemia. Borsi, J.D., Sagen, E., Romslo, I., Slørdal, L., Moe, P.J. Cancer Chemother. Pharmacol. (1990)
- Possible role of histamine in pathogenesis of autoimmune diseases: implications for immunotherapy with histamine-2 receptor antagonists. Nielsen, H.J., Hammer, J.H. Med. Hypotheses (1992)
- Effect of 5-fluorouracil combination therapy on RNA processing in human colonic carcinoma cells. Greenhalgh, D.A., Parish, J.H. Br. J. Cancer (1990)
- Quantitation of the synergistic interaction of edatrexate and cisplatin in vitro. Chou, T.C., Tan, Q.H., Sirotnak, F.M. Cancer Chemother. Pharmacol. (1993)
- Inhibition of 7-hydroxymethotrexate formation by amsacrine. Bremnes, R.M., Smeland, E., Willassen, N.P., Wist, E., Aarbakke, J. Cancer Chemother. Pharmacol. (1991)
- DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine. Kwok, J.B., Tattersall, M.H. Br. J. Cancer (1992)
- Role of neutrophils in indomethacin-induced gastric mucosal lesions in rats. Alican, I., Coşkun, T., Corak, A., Yeğen, B.C., Oktay, S., Kurtel, H. Inflamm. Res. (1995)
- Synthesis and antitumor activity of pyrrolo[2,3-d]pyrimidine antifolates with a bridge chain containing a nitrogen atom. Aso, K., Hitaka, T., Yukishige, K., Ootsu, K., Akimoto, H. Chem. Pharm. Bull. (1995)
- The effects of anticancer drugs on levels of nitric oxide and adrenomedullin. G??ler, E., Balat, A., Cekmen, M., Kilin??, M., Sivasli, E., Y??rekli, M., Duman, C. Turk. J. Pediatr. (2006)
- Phase II study of MTX-HSA in combination with Cisplatin as first line treatment in patients with advanced or metastatic transitional cell carcinoma. Bolling, C., Graefe, T., Lübbing, C., Jankevicius, F., Uktveris, S., Cesas, A., Meyer-Moldenhauer, W.H., Starkmann, H., Weigel, M., Burk, K., Hanauske, A.R. Investigational new drugs. (2006)
- Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries. Erdlenbruch, B., Alipour, M., Fricker, G., Miller, D.S., Kugler, W., Eibl, H., Lakomek, M. Br. J. Pharmacol. (2003)
- Development, recurrence, and severity of infections in Mexican patients with rheumatoid arthritis. A nested case-control study. Hernández-Cruz, B., Cardiel, M.H., Villa, A.R., Alcocer-Varela, J. J. Rheumatol. (1998)
- Antagonism of HSV-tk transfection and ganciclovir treatment on chemotherapeutic drug sensitivity. Van Dillen, I.J., Mulder, N.H., Meijer, C., Dam, W.A., Kamstra, E., De Vries, L., Meersma, G.J., Van der Zee, A.G., De Vries, E.F., Vaalburg, W., Hospers, G.A. Journal of chemotherapy (Florence, Italy) (2005)
- Etanercept Immunex. Yung, R.L. Current opinion in investigational drugs (London, England : 2000) (2001)
- Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells. Efferth, T., Miyachi, H., Drexler, H.G., Gebhart, E. Blood Cells Mol. Dis. (2002)
- Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis--new pathways to epitope spreading. Roth, E.B., Stenberg, P., Book, C., Sjöberg, K. Clin. Exp. Rheumatol. (2006)
- Clinical response following adjuvant Temozolomide in a patient with primary cerebral lymphoma. Strik, H.M., Spreer, A., Nagel, H., Jacob, S., Jung, W., Kitze, B., Bähr, M. Anticancer Res. (2004)
- Effect of neutropenia on gastric mucosal integrity and mucosal nitric oxide synthesis in the rat. Tepperman, B.L., Vozzolo, B.L., Soper, B.D. Dig. Dis. Sci. (1993)