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Chemical Compound Review

Cuprenil     (2R)-2-amino-3-methyl-3- sulfanyl-butanoic...

Synonyms: Cuprimine, Metalcaptase, penicillamine, Mercaptovaline, D-Penicillamine, ...
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Disease relevance of Cuprimine


Psychiatry related information on Cuprimine


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Chemical compound and disease context of Cuprimine


Biological context of Cuprimine


Anatomical context of Cuprimine


Associations of Cuprimine with other chemical compounds


Gene context of Cuprimine


Analytical, diagnostic and therapeutic context of Cuprimine


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  4. D-penicillamine-induced IgA deficiency in Wilson's disease. Proesmans, W., Jaeken, J., Eeckels, R. Lancet (1976) [Pubmed]
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  11. Immunosuppression by D-penicillamine in vitro. Inhibition of human T lymphocyte proliferation by copper- or ceruloplasmin-dependent generation of hydrogen peroxide and protection by monocytes. Lipsky, P.E. J. Clin. Invest. (1984) [Pubmed]
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  15. Methotrexate therapy in rheumatoid arthritis: 15 years experience. Hoffmeister, R.T. Am. J. Med. (1983) [Pubmed]
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  18. Pregnancy and cystinuria. Gregory, M.C., Mansell, M.A. Lancet (1983) [Pubmed]
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  20. Prevention of spontaneous hepatocellular carcinoma in Long-Evans cinnamon rats with hereditary hepatitis by the administration of D-penicillamine. Jong-Hon, K., Togashi, Y., Kasai, H., Hosokawa, M., Takeichi, N. Hepatology (1993) [Pubmed]
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  24. Influence of methotrexate and azathioprine on radiologic progression in rheumatoid arthritis. A randomized, double-blind study. Jeurissen, M.E., Boerbooms, A.M., van de Putte, L.B., Doesburg, W.H., Lemmens, A.M. Ann. Intern. Med. (1991) [Pubmed]
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  27. Which traditional measures should be used in rheumatoid arthritis clinical trials? Anderson, J.J., Felson, D.T., Meenan, R.F., Williams, H.J. Arthritis Rheum. (1989) [Pubmed]
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  31. KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line. Sugimoto, M., Inoue, T., Yamashita, M., Takeshita, K., Nakaike, S. Drugs under experimental and clinical research. (2002) [Pubmed]
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  33. Diagnosis of Wilson's disease in an asymptomatic sibling by DNA linkage analysis. Maier-Dobersberger, T., Mannhalter, C., Rack, S., Granditsch, G., Kaserer, K., Korninger, L., Steindl, P., Gangl, A., Ferenci, P. Gastroenterology (1995) [Pubmed]
  34. D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives. Matloff, D.S., Kaplan, M.M. Gastroenterology (1980) [Pubmed]
  35. Effects of anticopper therapy on hepatocellular mitochondria in patients with Wilson's disease: an ultrastructural and stereological study. Sternlieb, I., Feldmann, G. Gastroenterology (1976) [Pubmed]
  36. Fulminant Wilson's disease treated with postdilution hemofiltration and orthotopic liver transplantation. Rakela, J., Kurtz, S.B., McCarthy, J.T., Ludwig, J., Ascher, N.L., Bloomer, J.R., Claus, P.L. Gastroenterology (1986) [Pubmed]
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