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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

Temodal     3-methyl-2-oxo-1,3,4,5,8...

Synonyms: Temodar, Temozolamide, Temozolodida, temozolomida, temozolomide, ...
 
 
 
 Chinot,  Honore,  Figarella-Branger,  Dufour,  Martin,  Braguer,  Barrie,  Muracciole,  Grisoli,  Danson,  Ashcroft,  Ranson,  Thatcher,  Hodgetts,  Lomax,  Clamp,  Arance,  Lorigan,  Middleton,  Tentori,  Leonetti,  Graziani,  Scarsella,  Zupi,  d'Amati,  Bonmassar,  Portarena,  Nicholson,  Ames,  Vezina,  Krailo,  Reid,  Seibel,  Ettinger,  Reaman,  Liu-Mares,  Brandes,  Tosoni,  Monfardini,  Cavallo,  Reni,  Basso,  Vastola,  Ferreri,  Scopece,  Panucci,  Ermani,  Middleton,  Grob,  Coates,  Schadendorf,  Dreno,  Aamdal,  Seiter,  Statkevich,  Henz,  Fraass,  Kapp,  Cebon,  Thatcher,  Tilgen,  Fierlbeck,  Muller,  Gore,  Aaronson,  Weiss,  Hwu,  Livingston,  Williams,  Menell,  Foster,  Chapman,  Lamb,  Wolchok,  Quinn,  Merrell,  Krown,  Panageas,  Houghton,  Johns,  Walker,  Weinstock,  Stockert,  Nice,  Burgess,  Vitali,  Jungbluth,  Murone,  Perera,  Old,  Scott,  Luwor, Bakhtiar Yamini, Xiaohong Yu, Michael H. Wu, Donald W. Kufe, Thomas E. Darga, M. Eileen Dolan, Ralph R. Weichselbaum, Bakhtiar Yamini, Vinay Rawlani, Ralph R. Weichselbaum, Kai Bickenbach, Xiaohong Yu, Peter Pytel, Nicholas Galanopoulos, Jula Veerapong,  Natsume,  Hatano,  Ishii,  Tsuno,  Wakabayashi,  Yoshida,  Mizuno, Christina K. Augustine, Yasunori Yoshimoto, Henry S. Friedman, Douglas S. Tyler, Jin Soo Yoo, Francis Ali-Osman, Joseph R. Nevins, Patricia A. Zipfel, Anil Potti,  Antonadou,  Throuvalas,  Coliarakis,  Paraskevaidis,  Economou,  Karageorgis,  Sarris,  Hillner,  Middleton,  Agarwala,  Middlemas,  Stewart,  Kirstein,  Houghton,  Poquette,  Friedman,  Brent,  
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Disease relevance of Temodal

 

High impact information on Temodal

 

Chemical compound and disease context of Temodal

 

Biological context of Temodal

 

Anatomical context of Temodal

 

Associations of Temodal with other chemical compounds

 

Gene context of Temodal

 

Analytical, diagnostic and therapeutic context of Temodal

References

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  3. Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478. Johns, T.G., Luwor, R.B., Murone, C., Walker, F., Weinstock, J., Vitali, A.A., Perera, R.M., Jungbluth, A.A., Stockert, E., Old, L.J., Nice, E.C., Burgess, A.W., Scott, A.M. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  4. O6-benzylguanine potentiates the in vivo toxicity and clastogenicity of temozolomide and BCNU in mouse bone marrow. Chinnasamy, N., Rafferty, J.A., Hickson, I., Ashby, J., Tinwell, H., Margison, G.P., Dexter, T.M., Fairbairn, L.J. Blood (1997) [Pubmed]
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  14. Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine. Toft, N.J., Winton, D.J., Kelly, J., Howard, L.A., Dekker, M., te Riele, H., Arends, M.J., Wyllie, A.H., Margison, G.P., Clarke, A.R. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
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  16. Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy. Neff, T., Beard, B.C., Peterson, L.J., Anandakumar, P., Thompson, J., Kiem, H.P. Blood (2005) [Pubmed]
  17. Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea. Plowman, J., Waud, W.R., Koutsoukos, A.D., Rubinstein, L.V., Moore, T.D., Grever, M.R. Cancer Res. (1994) [Pubmed]
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  19. First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia. Brandes, A.A., Basso, U., Reni, M., Vastola, F., Tosoni, A., Cavallo, G., Scopece, L., Ferreri, A.J., Panucci, M.G., Monfardini, S., Ermani, M. J. Clin. Oncol. (2004) [Pubmed]
  20. Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma. Hwu, W.J., Krown, S.E., Menell, J.H., Panageas, K.S., Merrell, J., Lamb, L.A., Williams, L.J., Quinn, C.J., Foster, T., Chapman, P.B., Livingston, P.O., Wolchok, J.D., Houghton, A.N. J. Clin. Oncol. (2003) [Pubmed]
  21. Post hoc economic analysis of temozolomide versus dacarbazine in the treatment of advanced metastatic melanoma. Hillner, B.E., Agarwala, S., Middleton, M.R. J. Clin. Oncol. (2000) [Pubmed]
  22. The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma. Vredenburgh, J.J., Desjardins, A., Reardon, D.A., Peters, K.B., Herndon, J.E., Marcello, J., Kirkpatrick, J.P., Sampson, J.H., Bailey, L., Threatt, S., Friedman, A.H., Bigner, D.D., Friedman, H.S. Clin. Cancer Res. (2011) [Pubmed]
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