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Chemical Compound Review

POTASSIUM PERMANGANATE     potassium oxido-trioxo-manganese

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Chemical compound and disease context of POTASSIUM PERMANGANATE


Biological context of POTASSIUM PERMANGANATE


Anatomical context of POTASSIUM PERMANGANATE


Associations of POTASSIUM PERMANGANATE with other chemical compounds



  • Using potassium permanganate, which preferentially modifies single-stranded DNA, we show that a temperature-sensitive rad25(ts) mutant severely reduces the normally extensive promoter melting observed in vivo on the highly expressed genes TDH2 and PDC1 and on the induced heat shock gene HSP82 [30].
  • Interleukin-1 receptor antagonist inhibits calcium accumulation in in vivo chronic granuloma induced by potassium permanganate [31].
  • However, PR and glucocorticoid receptor, but not ER, are able to contact the 5'-methyl group of thymines found in position 3 of HREs, as shown by potassium permanganate interference [32].
  • Potassium permanganate reactivity shows that the two structure elements are not equivalent: with AsiA, the motA UP element-deleted promoter opens more slowly whereas the motA TC promoter opens like the wild type [33].
  • The DNAase I footprint of RNA polymerase at the cysG promoter reveals extended protection upstream of the transcript start, and studies with potassium permanganate as a probe suggest that the upstream region is distorted in open complexes [34].

Analytical, diagnostic and therapeutic context of POTASSIUM PERMANGANATE


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  4. Pre-existing distortions in nucleic acid structure aid polypurine tract selection by HIV-1 reverse transcriptase. Kvaratskhelia, M., Budihas, S.R., Le Grice, S.F. J. Biol. Chem. (2002) [Pubmed]
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  8. A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif. Duncan, R., Bazar, L., Michelotti, G., Tomonaga, T., Krutzsch, H., Avigan, M., Levens, D. Genes Dev. (1994) [Pubmed]
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  10. The incubation of laminin, collagen IV, and heparan sulfate proteoglycan at 35 degrees C yields basement membrane-like structures. Grant, D.S., Leblond, C.P., Kleinman, H.K., Inoue, S., Hassell, J.R. J. Cell Biol. (1989) [Pubmed]
  11. Localized melting and structural changes in the SV40 origin of replication induced by T-antigen. Borowiec, J.A., Hurwitz, J. EMBO J. (1988) [Pubmed]
  12. Covalent DNA binding by vaccinia topoisomerase results in unpairing of the thymine base 5' of the scissile bond. Sekiguchi, J., Shuman, S. J. Biol. Chem. (1996) [Pubmed]
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  18. RNA polymerase III transcription complexes on chromosomal 5S rRNA genes in vivo: TFIIIB occupancy and promoter opening. Costanzo, G., Camier, S., Carlucci, P., Burderi, L., Negri, R. Mol. Cell. Biol. (2001) [Pubmed]
  19. Dynamic aspects of DNA/protein interactions in the transcriptional initiation complex and the hormone-responsive domains of the phosphoenolpyruvate carboxykinase promoter in vivo. Faber, S., O'Brien, R.M., Imai, E., Granner, D.K., Chalkley, R. J. Biol. Chem. (1993) [Pubmed]
  20. Role of TrfA and DnaA proteins in origin opening during initiation of DNA replication of the broad host range plasmid RK2. Konieczny, I., Doran, K.S., Helinski, D.R., Blasina, A. J. Biol. Chem. (1997) [Pubmed]
  21. Reactivity of potassium permanganate and tetraethylammonium chloride with mismatched bases and a simple mutation detection protocol. Lambrinakos, A., Humphrey, K.E., Babon, J.J., Ellis, T.P., Cotton, R.G. Nucleic Acids Res. (1999) [Pubmed]
  22. Growth cones of cultured sympathetic neurons contain adrenergic vesicles. Landis, S.C. J. Cell Biol. (1978) [Pubmed]
  23. Altered cerebral vessel innervation in the spontaneously hypertensive rat. Lee, T.J., Saito, A. Circ. Res. (1984) [Pubmed]
  24. Density of sympathetic nerve terminals in human superficial temporal arteries: potassium permanganate fixation and monoamine oxidase histochemistry. Oka, N., Akiguchi, I., Matsubayashi, K., Kameyama, M., Maeda, T., Kawamura, J. Stroke (1987) [Pubmed]
  25. A non-toxic method for the demonstration of gliosis. Manlow, A., Munoz, D.G. J. Neuropathol. Exp. Neurol. (1992) [Pubmed]
  26. The FLP protein contacts both major and minor grooves of its recognition target sequence. Panigrahi, G.B., Beatty, L.G., Sadowski, P.D. Nucleic Acids Res. (1992) [Pubmed]
  27. Transcriptional Repressor CcpN from Bacillus subtilis Compensates Asymmetric Contact Distribution by Cooperative Binding. Licht, A., Brantl, S. J. Mol. Biol. (2006) [Pubmed]
  28. EBNA1 distorts oriP, the Epstein-Barr virus latent replication origin. Frappier, L., O'Donnell, M. J. Virol. (1992) [Pubmed]
  29. Potassium permanganate induced calcergy: a model to study the effects of drugs on hydroxyapatite crystal deposition. Doyle, D.V., Dunn, C.J., Willoughby, D.A. J. Pathol. (1979) [Pubmed]
  30. Transcription factor TFIIH is required for promoter melting in vivo. Guzmán, E., Lis, J.T. Mol. Cell. Biol. (1999) [Pubmed]
  31. Interleukin-1 receptor antagonist inhibits calcium accumulation in in vivo chronic granuloma induced by potassium permanganate. Conti, P., Reale, M., Panara, M.R., Fridas, S., Placido, F.C., Barbacane, R.C. Calcif. Tissue Int. (1993) [Pubmed]
  32. Functional interaction of hybrid response elements with wild-type and mutant steroid hormone receptors. Truss, M., Chalepakis, G., Slater, E.P., Mader, S., Beato, M. Mol. Cell. Biol. (1991) [Pubmed]
  33. Phage T4 early promoters are resistant to inhibition by the anti-sigma factor AsiA. Orsini, G., Igonet, S., Pène, C., Sclavi, B., Buckle, M., Uzan, M., Kolb, A. Mol. Microbiol. (2004) [Pubmed]
  34. The Escherichia coli cysG promoter belongs to the 'extended -10' class of bacterial promoters. Belyaeva, T., Griffiths, L., Minchin, S., Cole, J., Busby, S. Biochem. J. (1993) [Pubmed]
  35. Localization of endoplasmic reticulum in living and glutaraldehyde-fixed cells with fluorescent dyes. Terasaki, M., Song, J., Wong, J.R., Weiss, M.J., Chen, L.B. Cell (1984) [Pubmed]
  36. Central dual innervation of arterioles and capillaries in the brain. Itakura, T., Yamamoto, K., Tohyama, M., Shimizu, N. Stroke (1977) [Pubmed]
  37. Isolation and structure of the lipid envelopes from the nitrogen-fixing vesicles of Frankia sp. strain CpI1. Harriott, O.T., Khairallah, L., Benson, D.R. J. Bacteriol. (1991) [Pubmed]
  38. High concentration potassium permanganate eliminates protein and particle contamination of the reusable Classic laryngeal mask airway. Laupu, W., Laupau, W., Brimacombe, J., Richards, E., Keller, C. Anaesthesia. (2006) [Pubmed]
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