Gene Review:
Mgat5 - mannoside acetylglucosaminyltransferase 5
Mus musculus
Synonyms:
4930471A21Rik, 5330407H02Rik, AI480971, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, ...
- N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells. Morgan, R., Gao, G., Pawling, J., Dennis, J.W., Demetriou, M., Li, B. J. Immunol. (2004)
- Sequences of the mouse N-acetylglucosaminyltransferase V (Mgat5) mRNA and an mRNA expressed by an Mgat5-deficient cell line. Alverez, K., Haswell, C., St Clair, M., Perng, G.S., Shorebah, M., Pierce, M., Fregien, N. Glycobiology (2002)
- The her-2/neu oncogene stimulates the transcription of N-acetylglucosaminyltransferase V and expression of its cell surface oligosaccharide products. Chen, L., Zhang, W., Fregien, N., Pierce, M. Oncogene (1998)
- Preparation of antisera to recombinant, soluble N-acetylglucosaminyltransferase V and its visualization in situ. Chen, L., Zhang, N., Adler, B., Browne, J., Freigen, N., Pierce, M. Glycoconj. J. (1995)
- Glycoprotein glycosylation and cancer progression. Dennis, J.W., Granovsky, M., Warren, C.E. Biochim. Biophys. Acta (1999)
- Knockdown of Mgat5 inhibits breast cancer cell growth with activation of CD4+ T cells and macrophages. Li, D., Li, Y., Wu, X., Li, Q., Yu, J., Gen, J., Zhang, X.L. J. Immunol. (2008)
- Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue. Nishio, Y., Warren, C.E., Buczek-Thomas, J.A., Rulfs, J., Koya, D., Aiello, L.P., Feener, E.P., Miller, T.B., Dennis, J.W., King, G.L. J. Clin. Invest. (1995)
- Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. Demetriou, M., Nabi, I.R., Coppolino, M., Dedhar, S., Dennis, J.W. J. Cell Biol. (1995)
- Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis. Partridge, E.A., Le Roy, C., Di Guglielmo, G.M., Pawling, J., Cheung, P., Granovsky, M., Nabi, I.R., Wrana, J.L., Dennis, J.W. Science (2004)
- UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice. Dennis, J.W., Pawling, J., Cheung, P., Partridge, E., Demetriou, M. Biochim. Biophys. Acta (2002)
- GlcNAc-transferase V and core 2 GlcNAc-transferase expression in the developing mouse embryo. Granovsky, M., Fode, C., Warren, C.E., Campbell, R.M., Marth, J.D., Pierce, M., Fregien, N., Dennis, J.W. Glycobiology (1995)
- Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction. Priatel, J.J., Sarkar, M., Schachter, H., Marth, J.D. Glycobiology (1997)
- Minimal catalytic domain of N-acetylglucosaminyltransferase V. Korczak, B., Le, T., Elowe, S., Datti, A., Dennis, J.W. Glycobiology (2000)
- Galectin binding to Mgat5-modified N-glycans regulates fibronectin matrix remodeling in tumor cells. Lagana, A., Goetz, J.G., Cheung, P., Raz, A., Dennis, J.W., Nabi, I.R. Mol. Cell. Biol. (2006)
- Induction of N-acetylglucosaminyltransferase V by elevated expression of activated or proto-Ha-ras oncogenes. Lu, Y., Chaney, W. Mol. Cell. Biochem. (1993)
- Inhibition of N-linked oligosaccharide processing in tumor cells is associated with enhanced tissue inhibitor of metalloproteinases (TIMP) gene expression. Korczak, B., Dennis, J.W. Int. J. Cancer (1993)