Gene Review:
Fn1 - fibronectin 1
Mus musculus
Synonyms:
E330027I09, FN, Fibronectin, Fn, Fn-1
- Pancreas recovery following cerulein-induced pancreatitis is impaired in plasminogen-deficient mice. Lugea, A., Nan, L., French, S.W., Bezerra, J.A., Gukovskaya, A.S., Pandol, S.J. Gastroenterology (2006)
- Deletion of Protein Kinase C-{beta} Isoform In Vivo Reduces Renal Hypertrophy but Not Albuminuria in the Streptozotocin-Induced Diabetic Mouse Model. Meier, M., Park, J.K., Overheu, D., Kirsch, T., Lindschau, C., Gueler, F., Leitges, M., Menne, J., Haller, H. Diabetes (2007)
- Antigen-independent processes in antigen-specific immunity. A role for alpha 4 integrin. Ferguson, T.A., Kupper, T.S. J. Immunol. (1993)
- Inhibition of metastatic cell colonization in murine lungs and tumor-induced morbidity by non-peptidic Arg-Gly-Asp mimetics. Hardan, I., Weiss, L., Hershkoviz, R., Greenspoon, N., Alon, R., Cahalon, L., Reich, S., Slavin, S., Lider, O. Int. J. Cancer (1993)
- Fibronectin-binding protein I of Streptococcus pyogenes is a promising adjuvant for antigens delivered by mucosal route. Medina, E., Talay, S.R., Chhatwal, G.S., Guzmán, C.A. Eur. J. Immunol. (1998)
- Periodic lamellipodial contractions correlate with rearward actin waves. Giannone, G., Dubin-Thaler, B.J., Döbereiner, H.G., Kieffer, N., Bresnick, A.R., Sheetz, M.P. Cell (2004)
- Stereocilia defects in the sensory hair cells of the inner ear in mice deficient in integrin alpha8beta1. Littlewood Evans, A., Müller, U. Nat. Genet. (2000)
- Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Guan, J.L., Hynes, R.O. Cell (1990)
- Cultured tubule cells from TGF-beta1 null mice exhibit impaired hypertrophy and fibronectin expression in high glucose. Chen, S., Hoffman, B.B., Lee, J.S., Kasama, Y., Jim, B., Kopp, J.B., Ziyadeh, F.N. Kidney Int. (2004)
- Fibronectin receptor defects in NOD mouse leucocytes: possible consequences for type 1 diabetes. Geutskens, S.B., Mendes-da-Cruz, D.A., Dardenne, M., Savino, W. Scand. J. Immunol. (2004)
- Cell surface phosphatidylinositol-anchored heparan sulfate proteoglycan initiates mouse melanoma cell adhesion to a fibronectin-derived, heparin-binding synthetic peptide. Drake, S.L., Klein, D.J., Mickelson, D.J., Oegema, T.R., Furcht, L.T., McCarthy, J.B. J. Cell Biol. (1992)
- Modulation of melanoma cell adhesion to basement membrane components by retinoic acid. Edward, M., Gold, J.A., MacKie, R.M. J. Cell. Sci. (1989)
- Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy. Tan, X., Li, Y., Liu, Y. J. Am. Soc. Nephrol. (2006)
- Integrin-mediated neurite outgrowth in neuroblastoma cells depends on the activation of potassium channels. Arcangeli, A., Becchetti, A., Mannini, A., Mugnai, G., De Filippi, P., Tarone, G., Del Bene, M.R., Barletta, E., Wanke, E., Olivotto, M. J. Cell Biol. (1993)
- IgE alone stimulates mast cell adhesion to fibronectin via pathways similar to those used by IgE + antigen but distinct from those used by Steel factor. Lam, V., Kalesnikoff, J., Lee, C.W., Hernandez-Hansen, V., Wilson, B.S., Oliver, J.M., Krystal, G. Blood (2003)
- Adhesion and migration are differentially regulated in hematopoietic progenitor cells by cytokines and extracellular matrix. Strobel, E.S., Möbest, D., von Kleist, S., Dangel, M., Ries, S., Mertelsmann, R., Henschler, R. Blood (1997)
- Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis. Astrof, S., Crowley, D., George, E.L., Fukuda, T., Sekiguchi, K., Hanahan, D., Hynes, R.O. Mol. Cell. Biol. (2004)
- Costimulation of fibronectin receptor promotes Fc gamma R-mediated rescue of IL-3-dependent bone marrow-derived cells from apoptosis. Yoshikawa, H., Sakihama, T., Nakajima, Y., Tasaka, K. J. Immunol. (1996)
- Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Bohnsack, B.L., Lai, L., Dolle, P., Hirschi, K.K. Genes Dev. (2004)
- Impaired integrin-mediated adhesion and signaling in fibroblasts expressing a dominant-negative mutant PTP1B. Arregui, C.O., Balsamo, J., Lilien, J. J. Cell Biol. (1998)
- PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration. Zeng, L., Si, X., Yu, W.P., Le, H.T., Ng, K.P., Teng, R.M., Ryan, K., Wang, D.Z., Ponniah, S., Pallen, C.J. J. Cell Biol. (2003)
- Two integrin-binding peptides abrogate T cell-mediated immune responses in vivo. Ferguson, T.A., Mizutani, H., Kupper, T.S. Proc. Natl. Acad. Sci. U.S.A. (1991)
- FAK promotes organization of fibronectin matrix and fibrillar adhesions. Ilić, D., Kovacic, B., Johkura, K., Schlaepfer, D.D., Tomasević, N., Han, Q., Kim, J.B., Howerton, K., Baumbusch, C., Ogiwara, N., Streblow, D.N., Nelson, J.A., Dazin, P., Shino, Y., Sasaki, K., Damsky, C.H. J. Cell. Sci. (2004)
- Fibrillin-1 microfibril deposition is dependent on fibronectin assembly. Kinsey, R., Williamson, M.R., Chaudhry, S., Mellody, K.T., McGovern, A., Takahashi, S., Shuttleworth, C.A., Kielty, C.M. J. Cell. Sci. (2008)
- Identification of a novel recognition sequence for fibronectin within the NH2-terminal beta-sandwich domain of tissue transglutaminase. Hang, J., Zemskov, E.A., Lorand, L., Belkin, A.M. J. Biol. Chem. (2005)
- Analysis of integrin receptors for laminin and type IV collagen on metastatic B16 melanoma cells. Ramos, D.M., Berston, E.D., Kramer, R.H. Cancer Res. (1990)
- Expression of fibronectin and a fibronectin-binding molecule during preimplantation development in the mouse. Morin, N., Sullivan, R. Hum. Reprod. (1994)
- Smad3 deficiency ameliorates experimental obliterative bronchiolitis in a heterotopic tracheal transplantation model. Ramirez, A.M., Takagawa, S., Sekosan, M., Jaffe, H.A., Varga, J., Roman, J. Am. J. Pathol. (2004)
- Signal transduction in confluent C3H 10T1/2 cells. The role of focal adhesion kinase. Miłoszewska, J., Trembacz, H., Janik, P. Acta Biochim. Pol. (2001)
- Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Guan, J.L., Trevithick, J.E., Hynes, R.O. Cell Regul. (1991)
- Effects of fibronectin cleaved by neuropsin on cell adhesion and migration. Tani, N., Matsumoto, K., Ota, I., Yoshida, S., Takada, Y., Shiosaka, S., Matsuura, N. Neurosci. Res. (2001)
- Expression of the integrin subunit alpha8 in murine lung development. Wagner, T.E., Frevert, C.W., Herzog, E.L., Schnapp, L.M. J. Histochem. Cytochem. (2003)
- Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain. Gaudry, C.A., Verderio, E., Aeschlimann, D., Cox, A., Smith, C., Griffin, M. J. Biol. Chem. (1999)
- NG2 glial cells provide a favorable substrate for growing axons. Yang, Z., Suzuki, R., Daniels, S.B., Brunquell, C.B., Sala, C.J., Nishiyama, A. J. Neurosci. (2006)
- Alpha5beta1, alphaVbeta3 and the platelet-associated integrin alphaIIbbeta3 coordinately regulate adhesion and migration of differentiating mouse trophoblast cells. Rout, U.K., Wang, J., Paria, B.C., Armant, D.R. Dev. Biol. (2004)
- Reduction in fibronectin expression and alteration in cell morphology are coincident in NIH3T3 cells expressing a mutant E2F1 transcription factor. Jordan-Sciutto, K.L., Logan, T.J., Norton, P.A., Derfoul, A., Dodge, G.R., Hall, D.J. Exp. Cell Res. (1997)
- Involvement of HB-EGF and EGF receptor transactivation in TGF-beta-mediated fibronectin expression in mesangial cells. Uchiyama-Tanaka, Y., Matsubara, H., Mori, Y., Kosaki, A., Kishimoto, N., Amano, K., Higashiyama, S., Iwasaka, T. Kidney Int. (2002)
- Divide, accumulate, differentiate: cell condensation in skeletal development revisited. Hall, B.K., Miyake, T. Int. J. Dev. Biol. (1995)
- Steel factor and c-kit regulate cell-matrix adhesion. Kinashi, T., Springer, T.A. Blood (1994)
- Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis. Tan, M.H., Sun, Z., Opitz, S.L., Schmidt, T.E., Peters, J.H., George, E.L. Blood (2004)
- Maspin plays an essential role in early embryonic development. Gao, F., Shi, H.Y., Daughty, C., Cella, N., Zhang, M. Development (2004)
- Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Baluk, P., Morikawa, S., Haskell, A., Mancuso, M., McDonald, D.M. Am. J. Pathol. (2003)
- Assembly of exogenous fibronectin by fibronectin-null cells is dependent on the adhesive substrate. Bae, E., Sakai, T., Mosher, D.F. J. Biol. Chem. (2004)
- A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Gill, S.E., Pape, M.C., Khokha, R., Watson, A.J., Leco, K.J. Dev. Biol. (2003)
- Role of stem cell factor and c-kit signaling in regulation of fetal intestinal epithelial cell adhesion to fibronectin. Shimizu, M., Minakuchi, K., Tsuda, A., Hiroi, T., Tanaka, N., Koga, J., Kiyono, H. Exp. Cell Res. (2001)