Gene Review:
ECE1 - endothelin converting enzyme 1
Homo sapiens
Synonyms:
ECE-1, Endothelin-converting enzyme 1
Morawietz,
Goettsch,
Szibor,
Barton,
Shaw,
Hakim,
Zerkowski,
Holtz,
Awano,
Dawson,
Hunter,
Turner,
Usmani,
Dibas,
Prasanna,
Yorio,
Davenport,
Maguire,
Ihling,
Szombathy,
Bohrmann,
Brockhaus,
Schaefer,
Loeffler,
Eckman,
Watson,
Marlow,
Sambamurti,
Eckman,
López-Ongil,
Díez-Marqués,
Griera,
Rodríguez-Puyol,
Rodríguez-Puyol,
Tabrizchi,
Davenport,
Kuc,
Usmani,
Harden,
Maitland,
Turner,
Funalot,
Courbon,
Brousseau,
Poirier,
Berr,
Cambien,
Amouyel,
Schwartz,
Ducimetière,
- Biochemical characterization of endothelin-converting enzyme-1alpha in cultured skin-derived cells and its postulated role in the stimulation of melanogenesis in human epidermis. Hachiya, A., Kobayashi, T., Takema, Y., Imokawa, G. J. Biol. Chem. (2002)
- Endothelin system in oral squamous carcinoma cells: specific siRNA targeting of ECE-1 blocks cell proliferation. Awano, S., Dawson, L.A., Hunter, A.R., Turner, A.J., Usmani, B.A. Int. J. Cancer (2006)
- The endothelin system in human glioblastoma. Egidy, G., Eberl, L.P., Valdenaire, O., Irmler, M., Majdi, R., Diserens, A.C., Fontana, A., Janzer, R.C., Pinet, F., Juillerat-Jeanneret, L. Lab. Invest. (2000)
- Differential expression of neutral endopeptidase-24.11 (neprilysin) and endothelin-converting enzyme in human prostate cancer cell lines. Usmani, B.A., Harden, B., Maitland, N.J., Turner, A.J. Clin. Sci. (2002)
- Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. Eckman, E.A., Watson, M., Marlow, L., Sambamurti, K., Eckman, C.B. J. Biol. Chem. (2003)
- Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Baynash, A.G., Hosoda, K., Giaid, A., Richardson, J.A., Emoto, N., Hammer, R.E., Yanagisawa, M. Cell (1994)
- Contribution of endogenous generation of endothelin-1 to basal vascular tone. Haynes, W.G., Webb, D.J. Lancet (1994)
- Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo. Rossi, G.P., Colonna, S., Pavan, E., Albertin, G., Della Rocca, F., Gerosa, G., Casarotto, D., Sartore, S., Pauletto, P., Pessina, A.C. Circulation (1999)
- A loss-of-function mutation in the endothelin-converting enzyme 1 (ECE-1) associated with Hirschsprung disease, cardiac defects, and autonomic dysfunction. Hofstra, R.M., Valdenaire, O., Arch, E., Osinga, J., Kroes, H., Löffler, B.M., Hamosh, A., Meijers, C., Buys, C.H. Am. J. Hum. Genet. (1999)
- SLV-306. Solvay. Tabrizchi, R. Current opinion in investigational drugs (London, England : 2000) (2003)
- Regulation of endothelin-converting enzyme-1 expression in human neuroblastoma cells. Fisk, L., Nalivaeva, N.N., Turner, A.J. Exp. Biol. Med. (Maywood) (2006)
- Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: the EVA study. Funalot, B., Courbon, D., Brousseau, T., Poirier, O., Berr, C., Cambien, F., Amouyel, P., Schwartz, J.C., Ducimetière, P. J. Hypertens. (2004)
- Molecular pharmacology of endothelin converting enzymes. Turner, A.J., Murphy, L.J. Biochem. Pharmacol. (1996)
- Endothelin converting enzyme (ECE) activity in human vascular smooth muscle. Maguire, J.J., Johnson, C.M., Mockridge, J.W., Davenport, A.P. Br. J. Pharmacol. (1997)
- Angiotensin-converting enzyme inhibitor therapy prevents upregulation of endothelin-converting enzyme-1 in failing human myocardium. Morawietz, H., Goettsch, W., Szibor, M., Barton, M., Shaw, S., Hakim, K., Zerkowski, H.R., Holtz, J. Biochem. Biophys. Res. Commun. (2002)
- Crosstalk between mesangial and endothelial cells: angiotensin II down-regulates endothelin-converting enzyme 1. López-Ongil, S., Díez-Marqués, M.L., Griera, M., Rodríguez-Puyol, M., Rodríguez-Puyol, D. Cell. Physiol. Biochem. (2005)
- Development of an internally quenched fluorescent substrate selective for endothelin-converting enzyme-1. Johnson, G.D., Ahn, K. Anal. Biochem. (2000)
- Shear stress attenuates endothelin and endothelin-converting enzyme expression through oxidative stress. Masatsugu, K., Itoh, H., Chun, T.H., Saito, T., Yamashita, J., Doi, K., Inoue, M., Sawada, N., Fukunaga, Y., Sakaguchi, S., Sone, M., Yamahara, K., Yurugi, T., Nakao, K. Regul. Pept. (2003)
- Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines. Saleh, D., Furukawa, K., Tsao, M.S., Maghazachi, A., Corrin, B., Yanagisawa, M., Barnes, P.J., Giaid, A. Am. J. Respir. Cell Mol. Biol. (1997)
- Attenuation of hemolysate-induced cerebrovascular endothelial cell injury and of production of endothelin-1 and big endothelin-1 by an endothelin-converting enzyme inhibitor. Chang, C.Z., Winardi, D., Lin, C.L., Kwan, A.L., Jeng, A.Y., Kassell, N.F., Howng, S.L., Lee, K.S. Surgical neurology. (2002)
- Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line. Dibas, A., Prasanna, G., Yorio, T. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. (2005)
- Cellular expression of isoforms of endothelin-converting enzyme-1 (ECE-1c, ECE-1b and ECE-1a) and endothelin-converting enzyme-2. Davenport, A.P., Kuc, R.E. J. Cardiovasc. Pharmacol. (2000)
- Expression of endothelin-1, endothelin-converting enzyme, and endothelin receptors in chronic heart failure. Zolk, O., Quattek, J., Sitzler, G., Schrader, T., Nickenig, G., Schnabel, P., Shimada, K., Takahashi, M., Böhm, M. Circulation (1999)
- Endothelin. Davenport, A.P., Maguire, J.J. Handbook of experimental pharmacology. (2006)
- Processing of proendothelin-1 at the C-terminus of big endothelin-1 is essential for proteolysis by endothelin-converting enzyme-1 in vivo. Kido, T., Sawamura, T., Hoshikawa, H., D'Orléans-Juste, P., Denault, J.B., Leduc, R., Kimura, J., Masaki, T. Eur. J. Biochem. (1997)
- In vivo role of endothelin-converting enzyme-1 as examined by adenovirus-mediated overexpression in rats. Télémaque, S., Emoto, N., deWit, D., Yanagisawa, M. J. Cardiovasc. Pharmacol. (1998)
- Increased expression of endothelin-converting enzyme-1c isoform in response to high glucose levels in endothelial cells. Keynan, S., Khamaisi, M., Dahan, R., Barnes, K., Jackson, C.D., Turner, A.J., Raz, I. J. Vasc. Res. (2004)
- Coexpression of endothelin-converting enzyme-1 and endothelin-1 in different stages of human atherosclerosis. Ihling, C., Szombathy, T., Bohrmann, B., Brockhaus, M., Schaefer, H.E., Loeffler, B.M. Circulation (2001)
- Characterization of phosphoramidon-sensitive metalloproteinases with endothelin-converting enzyme activity in porcine lung membrane. Sawamura, T., Shinmi, O., Kishi, N., Sugita, Y., Yanagisawa, M., Goto, K., Masaki, T., Kimura, S. Biochim. Biophys. Acta (1993)