Gene Review:
Reg1 - regenerating islet-derived 1
Mus musculus
Synonyms:
Islet of Langerhans regenerating protein 1, Lithostathine-1, PSP, PTP, Pancreatic stone protein 1, ...
- Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta. Planas, R., Alba, A., Carrillo, J., Puertas, M.C., Ampudia, R., Pastor, X., Okamoto, H., Takasawa, S., Gurr, W., Pujol-Borrell, R., Verdaguer, J., Vives-Pi, M. Diabetologia (2006)
- Host cell responses to Listeria monocytogenes infection include differential transcription of host stress genes involved in signal transduction. Schwan, W.R., Goebel, W. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate. Schmidt, A., Rutledge, S.J., Endo, N., Opas, E.E., Tanaka, H., Wesolowski, G., Leu, C.T., Huang, Z., Ramachandaran, C., Rodan, S.B., Rodan, G.A. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Induction of the proliferative phenotype in differentiated myogenic cells by hypoxia. Butler, A.J., Eagleton, M.J., Wang, D., Howell, R.L., Strauch, A.R., Khasgiwala, V., Smith, H.C. J. Biol. Chem. (1991)
- The Yersinia tyrosine phosphatase YopH targets a novel adhesion-regulated signalling complex in macrophages. Black, D.S., Marie-Cardine, A., Schraven, B., Bliska, J.B. Cell. Microbiol. (2000)
- Hypomyelination and increased activity of voltage-gated K(+) channels in mice lacking protein tyrosine phosphatase epsilon. Peretz, A., Gil-Henn, H., Sobko, A., Shinder, V., Attali, B., Elson, A. EMBO J. (2000)
- CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase. Tan, J., Town, T., Mori, T., Wu, Y., Saxe, M., Crawford, F., Mullan, M. J. Neurosci. (2000)
- Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Pagliarini, D.J., Wiley, S.E., Kimple, M.E., Dixon, J.R., Kelly, P., Worby, C.A., Casey, P.J., Dixon, J.E. Mol. Cell (2005)
- Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. Cloutier, J.F., Veillette, A. J. Exp. Med. (1999)
- The motheaten mutation rescues B cell signaling and development in CD45-deficient mice. Pani, G., Siminovitch, K.A., Paige, C.J. J. Exp. Med. (1997)
- PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration. Zeng, L., Si, X., Yu, W.P., Le, H.T., Ng, K.P., Teng, R.M., Ryan, K., Wang, D.Z., Ponniah, S., Pallen, C.J. J. Cell Biol. (2003)
- Differences in phosphatase modulation of alpha4beta1 and alpha5beta1 integrin-mediated adhesion and migration of B16F1 cells. Hangan-Steinman, D., Ho, W.C., Shenoy, P., Chan, B.M., Morris, V.L. Biochem. Cell Biol. (1999)
- Identification of a cytoplasmic, phorbol ester-inducible isoform of protein tyrosine phosphatase epsilon. Elson, A., Leder, P. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon. Toledano-Katchalski, H., Tiran, Z., Sines, T., Shani, G., Granot-Attas, S., den Hertog, J., Elson, A. Mol. Cell. Biol. (2003)
- Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas. Lu, Y., Ponton, A., Okamoto, H., Takasawa, S., Herrera, P.L., Liu, J.L. Am. J. Physiol. Endocrinol. Metab. (2006)
- Differentially expressed proteins in the pancreas of diet-induced diabetic mice. Qiu, L., List, E.O., Kopchick, J.J. Mol. Cell Proteomics (2005)
- The role of protein tyrosine phosphatase 1B in Ras signaling. Dubé, N., Cheng, A., Tremblay, M.L. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Epidermal growth factor receptor and the adaptor protein p52Shc are specific substrates of T-cell protein tyrosine phosphatase. Tiganis, T., Bennett, A.M., Ravichandran, K.S., Tonks, N.K. Mol. Cell. Biol. (1998)
- The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor. Taniguchi, Y., London, R., Schinkmann, K., Jiang, S., Avraham, H. Blood (1999)
- Modulation of interferon-gamma-induced macrophage activation by phosphotyrosine phosphatases inhibition. Effect on murine Leishmaniasis progression. Olivier, M., Romero-Gallo, B.J., Matte, C., Blanchette, J., Posner, B.I., Tremblay, M.J., Faure, R. J. Biol. Chem. (1998)
- Analysis of morphological and functional maturation of neoislets generated in vitro from pancreatic ductal cells and their suitability for islet banking and transplantation. Katdare, M.R., Bhonde, R.R., Parab, P.B. J. Endocrinol. (2004)
- Physical and functional interactions between receptor-like protein-tyrosine phosphatase alpha and p59fyn. Bhandari, V., Lim, K.L., Pallen, C.J. J. Biol. Chem. (1998)
- Reduced tumorigenicity of murine leukemia cells expressing protein-tyrosine phosphatase, PTPepsilon C. Tanuma, N., Shima, H., Shimada, S., Kikuchi, K. Oncogene (2003)
- Tissue-specific expression in the salivary glands of transgenic mice. Mikkelsen, T.R., Brandt, J., Larsen, H.J., Larsen, B.B., Poulsen, K., Ingerslev, J., Din, N., Hjorth, J.P. Nucleic Acids Res. (1992)
- The protein tyrosine phosphatase epsilon gene maps to mouse chromosome 7 and human chromosome 10q26. Elson, A., Kozak, C.A., Morton, C.C., Weremowicz, S., Leder, P. Genomics (1996)