Gene Review:
ICOSLG - inducible T-cell co-stimulator ligand
Homo sapiens
Synonyms:
B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7H2, ...
Schmidt,
Rakocevic,
Raju,
Dalakas,
Okamoto,
Saito,
Yamanaka,
Tomatsu,
Kamatani,
Ogiuchi,
Uchiyama,
Yagi,
Petroff,
Kharatyan,
Torry,
Holets,
Wiendl,
Mitsdoerffer,
Schneider,
Melms,
Lochmuller,
Hohlfeld,
Weller,
Richter,
Hayden-Ledbetter,
Irgang,
Ledbetter,
Westermann,
Körner,
Daemen,
Clark,
Aicher,
Pezzutto,
Tamura,
Dan,
Tamada,
Nakamura,
Shioi,
Hyodo,
Wang,
Dong,
Chen,
Ogata,
- Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo. Schreiner, B., Wischhusen, J., Mitsdoerffer, M., Schneider, D., Bornemann, A., Melms, A., Tolosa, E., Weller, M., Wiendl, H. Glia (2003)
- Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia. Tamura, H., Dan, K., Tamada, K., Nakamura, K., Shioi, Y., Hyodo, H., Wang, S.D., Dong, H., Chen, L., Ogata, K. Clin. Cancer Res. (2005)
- Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies. Wiendl, H., Mitsdoerffer, M., Schneider, D., Melms, A., Lochmuller, H., Hohlfeld, R., Weller, M. Brain (2003)
- T-cell co-stimulation through B7RP-1 and ICOS. Yoshinaga, S.K., Whoriskey, J.S., Khare, S.D., Sarmiento, U., Guo, J., Horan, T., Shih, G., Zhang, M., Coccia, M.A., Kohno, T., Tafuri-Bladt, A., Brankow, D., Campbell, P., Chang, D., Chiu, L., Dai, T., Duncan, G., Elliott, G.S., Hui, A., McCabe, S.M., Scully, S., Shahinian, A., Shaklee, C.L., Van, G., Mak, T.W., Senaldi, G. Nature (1999)
- Treatment of murine lupus with CTLA4Ig. Finck, B.K., Linsley, P.S., Wofsy, D. Science (1994)
- Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. Ito, T., Yang, M., Wang, Y.H., Lande, R., Gregorio, J., Perng, O.A., Qin, X.F., Liu, Y.J., Gilliet, M. J. Exp. Med. (2007)
- Structural basis of inducible costimulator ligand costimulatory function: determination of the cell surface oligomeric state and functional mapping of the receptor binding site of the protein. Chattopadhyay, K., Bhatia, S., Fiser, A., Almo, S.C., Nathenson, S.G. J. Immunol. (2006)
- Involvement of inducible costimulator in the exaggerated memory B cell and plasma cell generation in systemic lupus erythematosus. Hutloff, A., Büchner, K., Reiter, K., Baelde, H.J., Odendahl, M., Jacobi, A., Dörner, T., Kroczek, R.A. Arthritis Rheum. (2004)
- The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta. Petroff, M.G., Kharatyan, E., Torry, D.S., Holets, L. Am. J. Pathol. (2005)
- Upregulated inducible co-stimulator (ICOS) and ICOS-ligand in inclusion body myositis muscle: significance for CD8+ T cell cytotoxicity. Schmidt, J., Rakocevic, G., Raju, R., Dalakas, M.C. Brain (2004)
- LICOS, a primordial costimulatory ligand? Brodie, D., Collins, A.V., Iaboni, A., Fennelly, J.A., Sparks, L.M., Xu, X.N., van der Merwe, P.A., Davis, S.J. Curr. Biol. (2000)
- Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS. Yoshinaga, S.K., Zhang, M., Pistillo, J., Horan, T., Khare, S.D., Miner, K., Sonnenberg, M., Boone, T., Brankow, D., Dai, T., Delaney, J., Han, H., Hui, A., Kohno, T., Manoukian, R., Whoriskey, J.S., Coccia, M.A. Int. Immunol. (2000)
- ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells. Khayyamian, S., Hutloff, A., Büchner, K., Gräfe, M., Henn, V., Kroczek, R.A., Mages, H.W. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Characterization of human inducible costimulator ligand expression and function. Aicher, A., Hayden-Ledbetter, M., Brady, W.A., Pezzutto, A., Richter, G., Magaletti, D., Buckwalter, S., Ledbetter, J.A., Clark, E.A. J. Immunol. (2000)
- Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34(+) progenitor cells during differentiation into antigen presenting cells. Richter, G., Hayden-Ledbetter, M., Irgang, M., Ledbetter, J.A., Westermann, J., Körner, I., Daemen, K., Clark, E.A., Aicher, A., Pezzutto, A. J. Biol. Chem. (2001)
- Expression and function of the co-stimulator H4/ICOS on activated T cells of patients with rheumatoid arthritis. Okamoto, T., Saito, S., Yamanaka, H., Tomatsu, T., Kamatani, N., Ogiuchi, H., Uchiyama, T., Yagi, J. J. Rheumatol. (2003)
- Expression of Costimulatory Molecules on Human Retinoblastoma Cells Y-79: Functional Expression of CD40 and B7H1. Usui, Y., Okunuki, Y., Hattori, T., Takeuchi, M., Kezuka, T., Goto, H., Usui, M. Invest. Ophthalmol. Vis. Sci. (2006)
- Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells. Kurosawa, S., Myers, A.C., Chen, L., Wang, S., Ni, J., Plitt, J.R., Heller, N.M., Bochner, B.S., Schleimer, R.P. Am. J. Respir. Cell Mol. Biol. (2003)