Gene Review:
CD276 - CD276 molecule
Homo sapiens
Synonyms:
4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, B7RP-2, ...
- Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro. Zhang, G.B., Chen, Y.J., Shi, Q., Ma, H.B., Ge, Y., Wang, Q., Jiang, Z., Xu, Y., Zhang, X.G. Acta Biochim. Biophys. Sin. (Shanghai) (2004)
- Phase I study of the intratumoral administration of recombinant canarypox viruses expressing B7.1 and interleukin 12 in patients with metastatic melanoma. Triozzi, P.L., Allen, K.O., Carlisle, R.R., Craig, M., LoBuglio, A.F., Conry, R.M. Clin. Cancer Res. (2005)
- HIV Coinfection Impairs CD28-Mediated Costimulation of Hepatitis C Virus-Specific CD8 Cells. Yonkers, N.L., Rodriguez, B., Post, A.B., Asaad, R., Jones, L., Lederman, M.M., Lehmann, P.V., Anthony, D.D. J. Infect. Dis. (2006)
- Trypanosoma cruzi Infection Induces Differential Modulation of Costimulatory Molecules and Cytokines by Monocytes and T Cells from Patients with Indeterminate and Cardiac Chagas' Disease. Souza, P.E., Rocha, M.O., Menezes, C.A., Coelho, J.S., Chaves, A.C., Gollob, K.J., Dutra, W.O. Infect. Immun. (2007)
- Immunobiological characterization of N -nitrosomethylurea-induced rat breast carcinomas: tumoral IL-10 expression as a possible immune escape mechanism. Hill, M., Bausero, M., Mazal, D., Ménoret, S., Khalife, J., Anegón, I., Osinaga, E. Breast Cancer Res. Treat. (2004)
- Human muscle cells express the costimulatory molecule B7-H3, which modulates muscle-immune interactions. Waschbisch, A., Wintterle, S., Lochmüller, H., Walter, M.C., Wischhusen, J., Kieseier, B.C., Wiendl, H. Arthritis Rheum. (2008)
- Sarcoidosis is associated with a truncating splice site mutation in BTNL2. Valentonyte, R., Hampe, J., Huse, K., Rosenstiel, P., Albrecht, M., Stenzel, A., Nagy, M., Gaede, K.I., Franke, A., Haesler, R., Koch, A., Lengauer, T., Seegert, D., Reiling, N., Ehlers, S., Schwinger, E., Platzer, M., Krawczak, M., Müller-Quernheim, J., Schürmann, M., Schreiber, S. Nat. Genet. (2005)
- Signals and signs for lymphocyte responses. Janeway, C.A., Bottomly, K. Cell (1994)
- Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. Sun, Y., Chen, H.M., Subudhi, S.K., Chen, J., Koka, R., Chen, L., Fu, Y.X. Nat. Med. (2002)
- Costimulatory regulation of T cell function. Chambers, C.A., Allison, J.P. Curr. Opin. Cell Biol. (1999)
- Soluble CD86 is a costimulatory molecule for human T lymphocytes. Jeannin, P., Magistrelli, G., Aubry, J.P., Caron, G., Gauchat, J.F., Renno, T., Herbault, N., Goetsch, L., Blaecke, A., Dietrich, P.Y., Bonnefoy, J.Y., Delneste, Y. Immunity (2000)
- Induction of costimulatory molecule B7 in M12 B lymphomas by cAMP or MHC-restricted T cell interaction. Watts, T.H., Alaverdi, N., Wade, W.F., Linsley, P.S. J. Immunol. (1993)
- Demethylation of the same promoter sequence increases CD70 expression in lupus T cells and T cells treated with lupus-inducing drugs. Lu, Q., Wu, A., Richardson, B.C. J. Immunol. (2005)
- Arsenic trioxide synergizes with B7H3-mediated immunotherapy to eradicate hepatocellular carcinomas. Luo, L., Qiao, H., Meng, F., Dong, X., Zhou, B., Jiang, H., Kanwar, J.R., Krissansen, G.W., Sun, X. Int. J. Cancer (2006)
- The role of costimulatory molecules (B7-1 and B7-2) on allergen-stimulated B cells in cedar pollinosis subjects. Morikawa, H., Nagashima, S. Clin. Exp. Allergy (2000)
- Human CD4+CD25high Regulatory T Cells Modulate Myeloid but Not Plasmacytoid Dendritic Cells Activation. Houot, R., Perrot, I., Garcia, E., Durand, I., Lebecque, S. J. Immunol. (2006)
- The immunomodulatory proteins B7-DC, B7-H2, and B7-H3 are differentially expressed across gestation in the human placenta. Petroff, M.G., Kharatyan, E., Torry, D.S., Holets, L. Am. J. Pathol. (2005)
- Characterization of mouse and human B7-H3 genes. Sun, M., Richards, S., Prasad, D.V., Mai, X.M., Rudensky, A., Dong, C. J. Immunol. (2002)
- B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production. Chapoval, A.I., Ni, J., Lau, J.S., Wilcox, R.A., Flies, D.B., Liu, D., Dong, H., Sica, G.L., Zhu, G., Tamada, K., Chen, L. Nat. Immunol. (2001)
- Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis. Castriconi, R., Dondero, A., Augugliaro, R., Cantoni, C., Carnemolla, B., Sementa, A.R., Negri, F., Conte, R., Corrias, M.V., Moretta, L., Moretta, A., Bottino, C. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Effect of pentoxifylline on differentiation and maturation of human monocyte-derived dendritic cells in vitro. Vukani??, Z.S., Coli??, M., Dimitrijevi??, M. Int. Immunopharmacol. (2007)
- Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. Matsuoka, N., Eguchi, K., Kawakami, A., Tsuboi, M., Kawabe, Y., Aoyagi, T., Nagataki, S. Clin. Exp. Immunol. (1996)
- Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-kappaB-mediated signalling, moderated by TGF-beta. Yan, M., Peng, J., Jabbar, I.A., Liu, X., Filgueira, L., Frazer, I.H., Thomas, R. Immunol. Cell Biol. (2005)
- Role of 4-1BB (CD137) in the functional activation of cord blood CD28(-)CD8(+) T cells. Kim, Y.J., Brutkiewicz, R.R., Broxmeyer, H.E. Blood (2002)
- Regulation of major histocompatibility complex class II antigens on human alveolar macrophages by granulocyte-macrophage colony-stimulating factor in the presence of glucocorticoids. Caulfield, J.J., Fernandez, M.H., Sousa, A.R., Lane, S.J., Lee, T.H., Hawrylowicz, C.M. Immunology (1999)
- Altered phenotype and function of blood dendritic cells in multiple sclerosis are modulated by IFN-beta and IL-10. Huang, Y.M., Stoyanova, N., Jin, Y.P., Teleshova, N., Hussien, Y., Xiao, B.G., Fredrikson, S., Link, H. Clin. Exp. Immunol. (2001)
- Polarized expression and function of the costimulatory molecule CD58 on human intestinal epithelial cells. Framson, P.E., Cho, D.H., Lee, L.Y., Hershberg, R.M. Gastroenterology (1999)
- Unique efficacy of Toll-like receptor 8 agonists in activating human neonatal antigen-presenting cells. Levy, O., Suter, E.E., Miller, R.L., Wessels, M.R. Blood (2006)
- Identification of a promoter element that regulates tissue-specific expression of the human CD80 (B7.1) gene. Fong, T.C., Wu, Y., Kipps, T.J. J. Immunol. (1996)
- Biochemical and functional characterization of three activated macrophage populations. Edwards, J.P., Zhang, X., Frauwirth, K.A., Mosser, D.M. J. Leukoc. Biol. (2006)
- Regulation of TCR-mediated T cell activation by TNF-RII. Aspalter, R.M., Eibl, M.M., Wolf, H.M. J. Leukoc. Biol. (2003)
- Self-tolerance in the immune privileged CNS: lessons from the entorhinal cortex lesion model. Kwidzinski, E., Mutlu, L.K., Kovac, A.D., Bunse, J., Goldmann, J., Mahlo, J., Aktas, O., Zipp, F., Kamradt, T., Nitsch, R., Bechmann, I. J. Neural Transm. Suppl. (2003)
- Expression of recombinant human ICOS and in vitro characterization of its bioactivity on B lymphocytes. Deng, Z.B., Lu, C.M., Huang, W.D., Shen, L.Q., Zhu, W., Ma, H.B., Fan, P.S., Zhang, X.G. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (2003)
- Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss. Ling, V., Wu, P.W., Spaulding, V., Kieleczawa, J., Luxenberg, D., Carreno, B.M., Collins, M. Genomics (2003)
- A Costimulatory Function for T Cell CD40. Munroe, M.E., Bishop, G.A. J. Immunol. (2007)
- B7H1-Ig Fusion Protein Activates the CD4+ IFN-{gamma} Receptor+ Type 1 T Regulatory Subset through IFN-{gamma}-Secreting Th1 Cells. Ding, Q., Lu, L., Wang, B., Zhou, Y., Jiang, Y., Zhou, X., Xin, L., Jiao, Z., Chou, K.Y. J. Immunol. (2006)
- Importance of the inducible costimulator molecule for the induction of allergic immune responses and its decreased expression on T helper cells after venom immunotherapy. Bellinghausen, I., Klostermann, B., Böttcher, I., Knop, J., Saloga, J. Immunology (2004)
- Inhibitory effects of interleukin-10 on synovial cells of rheumatoid arthritis. Kawakami, A., Eguchi, K., Matsuoka, N., Tsuboi, M., Urayama, S., Kawabe, Y., Aoyagi, T., Maeda, K., Nagataki, S. Immunology (1997)