Gene Review:
Spg7 - spastic paraplegia 7 homolog (human)
Mus musculus
Synonyms:
AI452278, AU015315, Cmar, PGN, Paraplegin, ...
- Hereditary spastic paraplegia: respiratory choke or unactivated substrate? Claypool, S.M., Koehler, C.M. Cell (2005)
- The Role of TLR2 In Vivo following Challenge with Staphylococcus aureus and Prototypic Ligands. Mullaly, S.C., Kubes, P. J. Immunol. (2006)
- Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan. Jawdat, D.M., Rowden, G., Marshall, J.S. J. Immunol. (2006)
- Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport. Ferreirinha, F., Quattrini, A., Pirozzi, M., Valsecchi, V., Dina, G., Broccoli, V., Auricchio, A., Piemonte, F., Tozzi, G., Gaeta, L., Casari, G., Ballabio, A., Rugarli, E.I. J. Clin. Invest. (2004)
- Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity. Supajatura, V., Ushio, H., Nakao, A., Akira, S., Okumura, K., Ra, C., Ogawa, H. J. Clin. Invest. (2002)
- SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Lenz, L.L., Mohammadi, S., Geissler, A., Portnoy, D.A. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Effect of ashwagandha on lipid peroxidation in stress-induced animals. Dhuley, J.N. Journal of ethnopharmacology. (1998)
- Bacterial peptidoglycan-induced tnf-alpha transcription is mediated through the transcription factors Egr-1, Elk-1, and NF-kappaB. Xu, Z., Dziarski, R., Wang, Q., Swartz, K., Sakamoto, K.M., Gupta, D. J. Immunol. (2001)
- Demonstration of peptidoglycan-binding sites on lymphocytes and macrophages by photoaffinity cross-linking. Dziarski, R. J. Biol. Chem. (1991)
- The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2. Michelsen, K.S., Aicher, A., Mohaupt, M., Hartung, T., Dimmeler, S., Kirschning, C.J., Schumann, R.R. J. Biol. Chem. (2001)
- Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities. Chisholm, D., Libet, L., Hayashi, T., Horner, A.A. J. Allergy Clin. Immunol. (2004)
- Variable and Tissue-Specific Subunit Composition of Mitochondrial m-AAA Protease Complexes Linked to Hereditary Spastic Paraplegia. Koppen, M., Metodiev, M.D., Casari, G., Rugarli, E.I., Langer, T. Mol. Cell. Biol. (2007)
- Involvement of SHIP in TLR2-induced neutrophil activation and acute lung injury. Strassheim, D., Kim, J.Y., Park, J.S., Mitra, S., Abraham, E. J. Immunol. (2005)
- Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver. Gustot, T., Lemmers, A., Moreno, C., Nagy, N., Quertinmont, E., Nicaise, C., Franchimont, D., Louis, H., Devière, J., Le Moine, O. Hepatology (2006)
- Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages. Chen, B.C., Chang, Y.S., Kang, J.C., Hsu, M.J., Sheu, J.R., Chen, T.L., Teng, C.M., Lin, C.H. J. Biol. Chem. (2004)
- Peptidoglycan induces transcription and secretion of TNF-alpha and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages. Gupta, D., Jin, Y.P., Dziarski, R. J. Immunol. (1995)
- Peptidoglycan-induced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, protein kinase A, I kappa B kinase, and NF-kappa B. Chen, B.C., Liao, C.C., Hsu, M.J., Liao, Y.T., Lin, C.C., Sheu, J.R., Lin, C.H. J. Immunol. (2006)
- Inhibitory effects of dimethylacetyl-beta-cyclodextrin on lipopolysaccharide-induced macrophage activation and endotoxin shock in mice. Arima, H., Motoyama, K., Matsukawa, A., Nishimoto, Y., Hirayama, F., Uekama, K. Biochem. Pharmacol. (2005)
- Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease. Visser, L., Jan de Heer, H., Boven, L.A., van Riel, D., van Meurs, M., Melief, M.J., Zähringer, U., van Strijp, J., Lambrecht, B.N., Nieuwenhuis, E.E., Laman, J.D. J. Immunol. (2005)
- Staphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia. Garg, S., Md Syed, M., Kielian, T. J. Neurochem. (2005)
- Toll-like receptor 2 (TLR2) is pivotal for recognition of S. aureus peptidoglycan but not intact bacteria by microglia. Kielian, T., Esen, N., Bearden, E.D. Glia (2005)
- Modification of allergic inflammation in murine model of rhinitis by different bacterial ligands: involvement of mast cells and dendritic cells. Yamamoto, K., Kawamura, I., Ito, J., Mitsuyama, M. Clin. Exp. Allergy (2006)