Gene Review:
Ptprc - protein tyrosine phosphatase, receptor...
Rattus norvegicus
Synonyms:
CD45, L-CA, Lca, Leukocyte common antigen, RT7, ...
- A point mutation in PTPRC is associated with the development of multiple sclerosis. Jacobsen, M., Schweer, D., Ziegler, A., Gaber, R., Schock, S., Schwinzer, R., Wonigeit, K., Lindert, R.B., Kantarci, O., Schaefer-Klein, J., Schipper, H.I., Oertel, W.H., Heidenreich, F., Weinshenker, B.G., Sommer, N., Hemmer, B. Nat. Genet. (2000)
- Induction of organ dysfunction and up-regulation of inflammatory markers in the liver and kidneys of hypotensive brain dead rats: a model to study marginal organ donors. van der Hoeven, J.A., Ploeg, R.J., Postema, F., Molema, I., de Vos, P., Girbes, A.R., van Suylichem, P.T., van Schilfgaarde, R., Ter Horst, G.J. Transplantation (1999)
- Role of Angiotensin-converting enzyme and neutral endopeptidase in flow-dependent remodeling. Korshunov, V.A., Massett, M.P., Carey, R.M., Berk, B.C. J. Vasc. Res. (2004)
- CD45 monoclonal antibody-mediated cytolysis of human NK and T lymphoma cells. Wulf, G.G., Boehnke, A., Chapuy, B., Glass, B., Hemmerlein, B., Schroers, R., Brenner, M.K., Truemper, L. Haematologica (2006)
- Experimental esophageal carcinogenesis: technical standardization and results. Sallet, J.A., Zilberstein, B., Andreollo, N.A., Eshkenazy, R., Pajecki, D. Dis. Esophagus (2002)
- Evidence from cDNA clones that the rat leukocyte-common antigen (T200) spans the lipid bilayer and contains a cytoplasmic domain of 80,000 Mr. Thomas, M.L., Barclay, A.N., Gagnon, J., Williams, A.F. Cell (1985)
- The functional relevance of passenger leukocytes and microchimerism for heart allograft acceptance in the rat. Ko, S., Deiwick, A., Jäger, M.D., Dinkel, A., Rohde, F., Fischer, R., Tsui, T.Y., Rittmann, K.L., Wonigeit, K., Schlitt, H.J. Nat. Med. (1999)
- Interconversion of CD45R subsets of CD4 T cells in vivo. Bell, E.B., Sparshott, S.M. Nature (1990)
- CD45RC isoforms define two types of CD4 memory T cells, one of which depends on persisting antigen. Bunce, C., Bell, E.B. J. Exp. Med. (1997)
- Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus. Barclay, A.N., Jackson, D.I., Willis, A.C., Williams, A.F. EMBO J. (1987)
- Rat osteotesticular phosphatase gene (Esp): genomic structure and chromosome location. Lathrop, W., Jordan, J., Eustice, D., Chen, D. Mamm. Genome (1999)
- Factors involved in regulation of the RT7 promoter in a male germ cell-derived in vitro transcription system. van der Hoorn, F.A., Tarnasky, H.A. Proc. Natl. Acad. Sci. U.S.A. (1992)
- In vivo depletion of hematopoietic stem cells in the rat by an anti-CD45 (RT7) antibody. Dahlke, M.H., Lauth, O.S., Jäger, M.D., Roeseler, T., Timrott, K., Jackobs, S., Neipp, M., Wonigeit, K., Schlitt, H.J. Blood (2002)
- Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts. Sedgwick, J.D., Ford, A.L., Foulcher, E., Airriess, R. J. Immunol. (1998)
- CD45 expression on rat acinar cells: involvement in pro-inflammatory cytokine production. De Dios, I., Ramudo, L., Alonso, J.R., Recio, J.S., Garcia-Montero, A.C., Manso, M.A. FEBS Lett. (2005)
- Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Sedgwick, J.D., Schwender, S., Imrich, H., Dörries, R., Butcher, G.W., ter Meulen, V. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Dendritic cells and resting B cells form clusters in vitro and in vivo: T cell independence, partial LFA-1 dependence, and regulation by cross-linking surface molecules. Kushnir, N., Liu, L., MacPherson, G.G. J. Immunol. (1998)
- Visualisation by low-angle shadowing of the leucocyte-common antigen. A major cell surface glycoprotein of lymphocytes. Woollett, G.R., Williams, A.F., Shotton, D.M. EMBO J. (1985)
- Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal. Haystead, T.A., Weiel, J.E., Litchfield, D.W., Tsukitani, Y., Fischer, E.H., Krebs, E.G. J. Biol. Chem. (1990)
- CD45-negative mutants of a rat natural killer cell line fail to lyse tumor target cells. Bell, G.M., Dethloff, G.M., Imboden, J.B. J. Immunol. (1993)
- Characterization of the interstitial cellular infiltrate in experimental chronic cyclosporine nephropathy. Gillum, D.M., Truong, L., Tasby, J. Transplantation (1990)
- Functional, morphological, and phenotypical differences between rat alveolar and interstitial macrophages. Johansson, A., Lundborg, M., Sköld, C.M., Lundahl, J., Tornling, G., Eklund, A., Camner, P. Am. J. Respir. Cell Mol. Biol. (1997)
- Organ-specific maturation of the major histocompatibility antigens in rats. Metzger, R., Parasta, A., Joppich, I., Till, H. Pediatr. Surg. Int. (2002)
- Effect of graft perfusion with two CD45 monoclonal antibodies on incidence of kidney allograft rejection. Brewer, Y., Palmer, A., Taube, D., Welsh, K., Bewick, M., Bindon, C., Hale, G., Waldmann, H., Dische, F., Parsons, V. Lancet (1989)
- Identification of the testis c-mos promoter: specific activity in a seminiferous tubule-derived extract and binding of a testis-specific nuclear factor. van der Hoorn, F.A. Oncogene (1992)
- Neurointermediate pituitary lobe cells synthesize and release interleukin-6 in vitro: effects of lipopolysaccharide and interleukin-1 beta. Spangelo, B.L., deHoll, P.D., Kalabay, L., Bond, B.R., Arnaud, P. Endocrinology (1994)
- VEGF164 is proinflammatory in the diabetic retina. Ishida, S., Usui, T., Yamashiro, K., Kaji, Y., Ahmed, E., Carrasquillo, K.G., Amano, S., Hida, T., Oguchi, Y., Adamis, A.P. Invest. Ophthalmol. Vis. Sci. (2003)