Gene Review:
Thy1 - Thy-1 cell surface antigen
Rattus norvegicus
Synonyms:
Thy-1, Thy-1 antigen, Thy-1 membrane glycoprotein
Chidlow,
Katoh,
Kita,
Fukatsu,
Osborne,
Kluth,
Melena,
Minto,
Holzhüter,
Wood,
Wilson,
Cailotto,
Macleod,
Lioznov,
Haites,
Lioznov,
Brown,
Shigematsu,
Mitani,
Mizuno,
Cupido,
Doi,
Yanagita,
Bergen,
Wilson,
Dijk,
Ohashi,
Fiegel,
Zander,
Fehse,
Kamphuis,
Ishii,
Fiegel,
Oite,
Fehse,
Varnum,
Nakano,
Martin,
Buijs,
Morioka,
Jaeschke-Melli,
Arai,
Kluth,
Whiting,
Suzuki,
Stewart,
Yao,
Park,
Zander,
Kaufmann,
Kluth,
- The characterization of a specific Thy-1 molecular epitope expressed on rat mesangial cells. Morioka, T., Yao, J., Suzuki, Y., Oite, T. Kidney Int. (2004)
- Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis. Tanaka, T., Matsumoto, M., Inagi, R., Miyata, T., Kojima, I., Ohse, T., Fujita, T., Nangaku, M. Kidney Int. (2005)
- Thy1 glomerulonephritis induced in young lewis rats accelerates age-related glomerulosclerosis. Stewart, K., Wilson, P., Wilson, H., Minto, A., Haites, N., Whiting, P., Macleod, A., Brown, P. Nephron (2001)
- A variable concept for the preparation of branched glycosyl phosphatidyl inositol anchors. Pekari, K., Schmidt, R.R. J. Org. Chem. (2003)
- Cell surface markers for distinguishing different types of rat dorsal root ganglion cells in culture. Fields, K.L., Brockes, J.P., Mirsky, R., Wendon, L.M. Cell (1978)
- Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein. Homans, S.W., Ferguson, M.A., Dwek, R.A., Rademacher, T.W., Anand, R., Williams, A.F. Nature (1988)
- Structural organization of the rat thy-1 gene. Seki, T., Moriuchi, T., Chang, H.C., Denome, R., Silver, J. Nature (1985)
- Mycophenolate mofetil and roscovitine decrease cyclin expression and increase p27(kip1) expression in anti Thy1 mesangial proliferative nephritis. Chiara, M., Menegatti, E., Di Simone, D., Davit, A., Bellis, D., Sferch, D., De Rosa, G., Giachino, O., Sena, L.M., Roccatello, D. Clin. Exp. Immunol. (2005)
- Agmatine inhibits cell proliferation and improves renal function in anti-thy-1 glomerulonephritis. Ishizuka, S., Cunard, R., Poucell-Hatton, S., Wead, L., Lortie, M., Thomson, S.C., Gabbai, F.B., Satriano, J., Blantz, R.C. J. Am. Soc. Nephrol. (2000)
- Thy-1-mediated phosphatidylinositol turnover in cultured rat glomerular mesangial cell. Narisawa-Saito, M., Kimura, S., Fujiwara, N., Oite, T., Shimoji, K., Shimizu, F. J. Cell. Physiol. (1996)
- Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity. Osborne, N.N., Wood, J.P., Cupido, A., Melena, J., Chidlow, G. Invest. Ophthalmol. Vis. Sci. (2002)
- Recombinant glycosyl-phosphatidylinositol-anchored proteins are not associated with protein kinases in transfected thymoma cells. Clissold, P.M. Biochem. J. (1994)
- Thy-1 cDNA sequence suggests a novel regulatory mechanism. Moriuchi, T., Chang, H.C., Denome, R., Silver, J. Nature (1983)
- Tissue-specific N-glycosylation, site-specific oligosaccharide patterns and lentil lectin recognition of rat Thy-1. Parekh, R.B., Tse, A.G., Dwek, R.A., Williams, A.F., Rademacher, T.W. EMBO J. (1987)
- Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. Avalos, A.M., Arthur, W.T., Schneider, P., Quest, A.F., Burridge, K., Leyton, L. J. Biol. Chem. (2004)
- Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity. Barker, T.H., Grenett, H.E., MacEwen, M.W., Tilden, S.G., Fuller, G.M., Settleman, J., Woods, A., Murphy-Ullrich, J., Hagood, J.S. Exp. Cell Res. (2004)
- Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. Pippin, J.W., Qu, Q., Meijer, L., Shankland, S.J. J. Clin. Invest. (1997)
- Gas6 regulates mesangial cell proliferation through Axl in experimental glomerulonephritis. Yanagita, M., Arai, H., Ishii, K., Nakano, T., Ohashi, K., Mizuno, K., Varnum, B., Fukatsu, A., Doi, T., Kita, T. Am. J. Pathol. (2001)
- Hepatic lineages isolated from developing rat liver show different ways of maturation. Fiegel, H.C., Kluth, J., Lioznov, M.V., Holzhüter, S., Fehse, B., Zander, A.R., Kluth, D. Biochem. Biophys. Res. Commun. (2003)
- Tracking movements of lipids and Thy1 molecules in the plasmalemma of living fibroblasts by fluorescence video microscopy with nanometer scale precision. Hicks, B.W., Angelides, K.J. J. Membr. Biol. (1995)
- Comparison of hepatic properties and transplantation of Thy-1(+) and Thy-1(-) cells isolated from embryonic day 14 rat fetal liver. Oertel, M., Menthena, A., Chen, Y.Q., Shafritz, D.A. Hepatology (2007)
- Thy-1 is a neuronal and glial surface antigen which interacts with matrix proteins and plasminogen activator. Liësi, P., Salonen, E.M., Dahl, D., Vaheri, A., Richards, S.J. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1990)
- Protein tyrosine kinase Syk is involved in Thy-1 signaling in rat basophilic leukemia cells. Tolar, P., Dráberová, L., Dráber, P. Eur. J. Immunol. (1997)
- C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. Han, W., Rhee, J.S., Maximov, A., Lin, W., Hammer, R.E., Rosenmund, C., Südhof, T.C. J. Biol. Chem. (2005)
- Angiogenic protein Cyr61 is expressed by podocytes in anti-Thy-1 glomerulonephritis. Sawai, K., Mori, K., Mukoyama, M., Sugawara, A., Suganami, T., Koshikawa, M., Yahata, K., Makino, H., Nagae, T., Fujinaga, Y., Yokoi, H., Yoshioka, T., Yoshimoto, A., Tanaka, I., Nakao, K. J. Am. Soc. Nephrol. (2003)
- Expression and localization of cyclooxygenase isoforms and cytosolic phospholipase A2 in anti-Thy-1 glomerulonephritis. Hirose, S., Yamamoto, T., Feng, L., Yaoita, E., Kawasaki, K., Goto, S., Fujinaka, H., Wilson, C.B., Arakawa, M., Kihara, I. J. Am. Soc. Nephrol. (1998)
- Participation of the matrix metalloproteinase inhibitor in Thy-1 nephritis. Mitani, O., Katoh, M., Shigematsu, H. Pathol. Int. (2004)
- The membrane domains occupied by glycosylphosphatidylinositol-anchored prion protein and Thy-1 differ in lipid composition. Brügger, B., Graham, C., Leibrecht, I., Mombelli, E., Jen, A., Wieland, F., Morris, R. J. Biol. Chem. (2004)
- Pentoxifylline inhibits platelet-derived growth factor-stimulated cyclin D1 expression in mesangial cells by blocking Akt membrane translocation. Lin, S.L., Chen, R.H., Chen, Y.M., Chiang, W.C., Tsai, T.J., Hsieh, B.S. Mol. Pharmacol. (2003)
- Circadian expression of clock genes and clock-controlled genes in the rat retina. Kamphuis, W., Cailotto, C., Dijk, F., Bergen, A., Buijs, R.M. Biochem. Biophys. Res. Commun. (2005)
- Role of Thy-1 in in vivo and in vitro neural development and regeneration of dorsal root ganglionic neurons. Chen, C.H., Wang, S.M., Yang, S.H., Jeng, C.J. J. Cell. Biochem. (2005)
- Characterization of cell types during rat liver development. Fiegel, H.C., Park, J.J., Lioznov, M.V., Martin, A., Jaeschke-Melli, S., Kaufmann, P.M., Fehse, B., Zander, A.R., Kluth, D. Hepatology (2003)
- Activation of STAT3/Smad1 is a key signaling pathway for progression to glomerulosclerosis in experimental glomerulonephritis. Takahashi, T., Abe, H., Arai, H., Matsubara, T., Nagai, K., Matsuura, M., Iehara, N., Yokode, M., Nishikawa, S., Kita, T., Doi, T. J. Biol. Chem. (2005)