Gene Review:
IL4 - interleukin 4
Bos taurus
Synonyms:
BSF-1, IL-4
Wedlock,
Skinner,
Parlane,
Vordermeier,
Hewinson,
de Lisle,
Buddle,
Graham,
Trees,
Collins,
Moore,
Guy,
Taylor,
Bianco,
Fayer,
Gasbarre,
Pasquali,
Canals,
Almeria,
Zarlenga,
Rhodes,
Palmer,
Graham,
Bianco,
Hewinson,
Vordermeier,
Menge,
Blessenohl,
Eisenberg,
Stamm,
Baljer,
Brown,
McElwain,
Palmer,
Chantler,
Estes,
- Development and in vitro characterization of recombinant vaccinia viruses expressing bovine leukemia virus gp51 in combination with bovine IL4 or IL12. Von Beust, B.R., Brown, W.C., Estes, D.M., Zarlenga, D.S., McElwain, T.F., Palmer, G.H. Vaccine (1999)
- Role of the bovine immune system and genome in resistance to gastrointestinal nematodes. Gasbarre, L.C., Leighton, E.A., Sonstegard, T. Vet. Parasitol. (2001)
- Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis. Rhodes, S.G., Palmer, N., Graham, S.P., Bianco, A.E., Hewinson, R.G., Vordermeier, H.M. Infect. Immun. (2000)
- Insulin and interleukin-4 induce desensitization to the mitogenic effects of insulin-like growth factor-I. Pivotal role for insulin receptor substrate-2. Haddad, T.C., Conover, C.A. J. Biol. Chem. (1997)
- In vitro cellular immune responses to recombinant antigens of Mycobacterium avium subsp. paratuberculosis. Shin, S.J., Chang, C.F., Chang, C.D., McDonough, S.P., Thompson, B., Yoo, H.S., Chang, Y.F. Infect. Immun. (2005)
- Bovine ileal intraepithelial lymphocytes represent target cells for Shiga toxin 1 from Escherichia coli. Menge, C., Blessenohl, M., Eisenberg, T., Stamm, I., Baljer, G. Infect. Immun. (2004)
- Cytokine responses of bovine dendritic cells and T cells following exposure to live or inactivated bovine respiratory syncytial virus. Werling, D., Collins, R.A., Taylor, G., Howard, C.J. J. Leukoc. Biol. (2002)
- The bovine interleukin-4 gene: genomic organization, localization, and evolution. Buitkamp, J., Schwaiger, F.W., Solinas-Toldo, S., Fries, R., Epplen, J.T. Mamm. Genome (1995)
- A microsatellite (BOBT24) located between the bovine IL4 and IL13 loci is polymorphic in cattle and goat. Buitkamp, J., Obexer-Ruff, G., Kessler, M., Epplen, J.T. Anim. Genet. (1996)
- Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis. Graham, S.P., Trees, A.J., Collins, R.A., Moore, D.M., Guy, F.M., Taylor, M.J., Bianco, A.E. Infect. Immun. (2001)
- A novel protein expression strategy using recombinant bovine respiratory syncytial virus (BRSV): modifications of the peptide sequence between the two furin cleavage sites of the BRSV fusion protein yield secreted proteins, but affect processing and function of the BRSV fusion protein. König, P., Giesow, K., Schuldt, K., Buchholz, U.J., Keil, G.M. J. Gen. Virol. (2004)
- Mechanisms of interleukin-4 effects on calcium signaling in airway smooth muscle cells. Ethier, M.F., Cappelluti, E., Madison, J.M. J. Pharmacol. Exp. Ther. (2005)
- Bovine CD4(+) T-lymphocyte clones specific for rhoptry-associated protein 1 of Babesia bigemina stimulate enhanced immunoglobulin G1 (IgG1) and IgG2 synthesis. Brown, W.C., McElwain, T.F., Palmer, G.H., Chantler, S.E., Estes, D.M. Infect. Immun. (1999)
- CD4+ T-cell clones obtained from cattle chronically infected with Fasciola hepatica and specific for adult worm antigen express both unrestricted and Th2 cytokine profiles. Brown, W.C., Davis, W.C., Dobbelaere, D.A., Rice-Ficht, A.C. Infect. Immun. (1994)
- Bacterial lipopolysaccharide-stimulated nitric oxide generation is unrelated to concurrent cytotoxicity of bovine alveolar macrophages. Bochsler, P.N., Mason, G.L., Olchowy, T.W., Yang, Z. Inflammation (1996)
- Vaccination with DNA vaccines encoding MPB70 or MPB83 or a MPB70 DNA prime-protein boost does not protect cattle against bovine tuberculosis. Wedlock, D.N., Skinner, M.A., Parlane, N.A., Vordermeier, H.M., Hewinson, R.G., de Lisle, G.W., Buddle, B.M. Tuberculosis (Edinburgh, Scotland) (2003)
- Characterization of protective immune responses in local lymphoid tissues after drug-attenuated infections with Ostertagia ostertagi in calves. Almería, S., Canals, A., Gómez-Muñoz, M.T., Zarlenga, D.S., Gasbarre, L.C. Vet. Parasitol. (1998)
- Cryptosporidium parvum infection in bovine neonates: dynamic clinical, parasitic and immunologic patterns. Fayer, R., Gasbarre, L., Pasquali, P., Canals, A., Almeria, S., Zarlenga, D. Int. J. Parasitol. (1998)
- Cloning of a full-length cDNA encoding bovine interleukin 4 by the polymerase chain reaction. Heussler, V.T., Eichhorn, M., Dobbelaere, D.A. Gene (1992)
- Efficacy of a pour-on formulation of eprinomectin (MK-397) against nematode parasites of cattle, with emphasis on inhibited early fourth-stage larvae of Ostertagia spp. Williams, J.C., Stuedemann, J.A., Bairden, K., Kerboeuf, D., Ciordia, H., Hubert, J., Broussard, S.D., Plue, R.E., Alva-Valdes, R., Baggott, D.G., Pinkall, N., Eagleson, J.S. Am. J. Vet. Res. (1997)