Gene Review:
SLC25A4 - solute carrier family 25 (mitochondrial...
Homo sapiens
Synonyms:
AAC1, ADP,ATP carrier protein 1, ADP,ATP carrier protein, heart/skeletal muscle isoform T1, ADP/ATP translocase 1, ANT, ...
Sharer,
Laoudj-Chenivesse,
Carnac,
Bisbal,
Hugon,
Bouillot,
Desnuelle,
Vassetzky,
Fernandez,
Dijkstra,
Borland,
Shirom,
Westman,
Shamai,
Carel,
Armstrong,
Jones,
Oldfors,
Moslemi,
Jonasson,
Ohlsson,
Kollberg,
Lindberg,
O'Gorman,
Beutner,
Dolder,
Koretsky,
Brdiczka,
Wallimann,
Dörner,
Giessen,
Gaub,
Grosse Siestrup,
Schwimmbeck,
Hetzer,
Poller,
Schultheiss,
- Increased levels of adenine nucleotide translocator 1 protein and response to oxidative stress are early events in facioscapulohumeral muscular dystrophy muscle. Laoudj-Chenivesse, D., Carnac, G., Bisbal, C., Hugon, G., Bouillot, S., Desnuelle, C., Vassetzky, Y., Fernandez, A. J. Mol. Med. (2005)
- Deficiency of the adenine nucleotide translocator in muscle of a patient with myopathy and lactic acidosis: a new mitochondrial defect. Bakker, H.D., Scholte, H.R., Van den Bogert, C., Ruitenbeek, W., Jeneson, J.A., Wanders, R.J., Abeling, N.G., Dorland, B., Sengers, R.C., Van Gennip, A.H. Pediatr. Res. (1993)
- An isoform shift in the cardiac adenine nucleotide translocase expression alters the kinetic properties of the carrier in dilated cardiomyopathy. Dörner, A., Giessen, S., Gaub, R., Grosse Siestrup, H., Schwimmbeck, P.L., Hetzer, R., Poller, W., Schultheiss, H.P. Eur. J. Heart Fail. (2006)
- A helicase is born. Moraes, C.T. Nat. Genet. (2001)
- Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2. Jacotot, E., Ferri, K.F., El Hamel, C., Brenner, C., Druillennec, S., Hoebeke, J., Rustin, P., Métivier, D., Lenoir, C., Geuskens, M., Vieira, H.L., Loeffler, M., Belzacq, A.S., Briand, J.P., Zamzami, N., Edelman, L., Xie, Z.H., Reed, J.C., Roques, B.P., Kroemer, G. J. Exp. Med. (2001)
- Autosomal dominant external ophthalmoplegia and bipolar affective disorder associated with a mutation in the ANT1 gene. Siciliano, G., Tessa, A., Petrini, S., Mancuso, M., Bruno, C., Grieco, G.S., Malandrini, A., DeFlorio, L., Martini, B., Federico, A., Nappi, G., Santorelli, F.M., Murri, L. Neuromuscul. Disord. (2003)
- Residual outcome expectations and relapse in ex-smokers. Dijkstra, A., Borland, R. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. (2003)
- Cultural affiliation and self-esteem as predictors of internalizing symptoms among mexican american adolescents. McDonald, E.J., McCabe, K., Yeh, M., Lau, A., Garland, A., Hough, R.L. Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. (2005)
- Effects of work overload and burnout on cholesterol and triglycerides levels: the moderating effects of emotional reactivity among male and female employees. Shirom, A., Westman, M., Shamai, O., Carel, R.S. Journal of occupational health psychology. (1997)
- Mental development and learning disorders in children with single suture craniosynostosis. Kapp-Simon, K.A. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association. (1998)
- Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Marzo, I., Brenner, C., Zamzami, N., Jürgensmeier, J.M., Susin, S.A., Vieira, H.L., Prévost, M.C., Xie, Z., Matsuyama, S., Reed, J.C., Kroemer, G. Science (1998)
- Plant mitochondria actively import DNA via the permeability transition pore complex. Koulintchenko, M., Konstantinov, Y., Dietrich, A. EMBO J. (2003)
- Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence. Ahlers, J.D., Takeshita, T., Pendleton, C.D., Berzofsky, J.A. Proc. Natl. Acad. Sci. U.S.A. (1997)
- 31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure. Neubauer, S., Krahe, T., Schindler, R., Horn, M., Hillenbrand, H., Entzeroth, C., Mader, H., Kromer, E.P., Riegger, G.A., Lackner, K. Circulation (1992)
- Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability. Fontanesi, F., Palmieri, L., Scarcia, P., Lodi, T., Donnini, C., Limongelli, A., Tiranti, V., Zeviani, M., Ferrero, I., Viola, A.M. Hum. Mol. Genet. (2004)
- Chemosensitization by knockdown of adenine nucleotide translocase-2. Le Bras, M., Borgne-Sanchez, A., Touat, Z., El Dein, O.S., Deniaud, A., Maillier, E., Lecellier, G., Rebouillat, D., Lemaire, C., Kroemer, G., Jacotot, E., Brenner, C. Cancer Res. (2006)
- Type Ic, a novel glycogenosis. Underlying mechanism. Nordlie, R.C., Sukalski, K.A., Muñoz, J.M., Baldwin, J.J. J. Biol. Chem. (1983)
- The adenine nucleotide translocase type 1 (ANT1): a new factor in mitochondrial disease. Sharer, J.D. IUBMB Life (2005)
- Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells. Armstrong, J.S., Jones, D.P. FASEB J. (2002)
- Studies on the primary and secondary structure of potato spindle tuber viroid: products of digestion with ribonuclease A and ribonuclease T1, and modification with bisulfite. Domdey, H., Jank, P., Sänger, L., Gross, H.J. Nucleic Acids Res. (1978)
- A novel D104G mutation in the adenine nucleotide translocator 1 gene in autosomal dominant progressive external ophthalmoplegia patients with mitochondrial DNA with multiple deletions. Komaki, H., Fukazawa, T., Houzen, H., Yoshida, K., Nonaka, I., Goto, Y. Ann. Neurol. (2002)
- A human muscle adenine nucleotide translocator gene has four exons, is located on chromosome 4, and is differentially expressed. Li, K., Warner, C.K., Hodge, J.A., Minoshima, S., Kudoh, J., Fukuyama, R., Maekawa, M., Shimizu, Y., Shimizu, N., Wallace, D.C. J. Biol. Chem. (1989)
- DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase. Cozens, A.L., Runswick, M.J., Walker, J.E. J. Mol. Biol. (1989)
- Adenine nucleotide translocator 1 deficiency associated with Sengers syndrome. Jordens, E.Z., Palmieri, L., Huizing, M., van den Heuvel, L.P., Sengers, R.C., Dörner, A., Ruitenbeek, W., Trijbels, F.J., Valsson, J., Sigfusson, G., Palmieri, F., Smeitink, J.A. Ann. Neurol. (2002)
- Recruitment of NF-kappaB into mitochondria is involved in adenine nucleotide translocase 1 (ANT1)-induced apoptosis. Zamora, M., Meroño, C., Viñas, O., Mampel, T. J. Biol. Chem. (2004)
- Microcompartmentation of energy metabolism at the outer mitochondrial membrane: role in diabetes mellitus and other diseases. McCabe, E.R. J. Bioenerg. Biomembr. (1994)
- Solution NMR of proteins within polyacrylamide gels: diffusional properties and residual alignment by mechanical stress or embedding of oriented purple membranes. Sass, H.J., Musco, G., Stahl, S.J., Wingfield, P.T., Grzesiek, S. J. Biomol. NMR (2000)
- The role of creatine kinase in inhibition of mitochondrial permeability transition. O'Gorman, E., Beutner, G., Dolder, M., Koretsky, A.P., Brdiczka, D., Wallimann, T. FEBS Lett. (1997)
- Human mitochondrial transmembrane metabolite carriers: tissue distribution and its implication for mitochondrial disorders. Huizing, M., Ruitenbeek, W., van den Heuvel, L.P., Dolce, V., Iacobazzi, V., Smeitink, J.A., Palmieri, F., Trijbels, J.M. J. Bioenerg. Biomembr. (1998)
- Ventricular adenine nucleotide translocator mRNA is upregulated in dilated cardiomyopathy. Sylvén, C., Lin, L., Jansson, E., Sotonyi, P., Fu, L.X., Waagstein, F., Hjalmarsson, A., Marcus, C., Brönnegård, M. Cardiovasc. Res. (1993)
- New EMBO members' review: viral and bacterial proteins regulating apoptosis at the mitochondrial level. Boya, P., Roques, B., Kroemer, G. EMBO J. (2001)
- Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men. Kupelian, V., Page, S.T., Araujo, A.B., Travison, T.G., Bremner, W.J., McKinlay, J.B. J. Clin. Endocrinol. Metab. (2006)
- Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population. González-Vioque, E., Blázquez, A., Fernández-Moreira, D., Bornstein, B., Bautista, J., Arpa, J., Navarro, C., Campos, Y., Fernández-Moreno, M.A., Garesse, R., Arenas, J., Martín, M.A. Arch. Neurol. (2006)
- ANT2 isoform required for cancer cell glycolysis. Chevrollier, A., Loiseau, D., Chabi, B., Renier, G., Douay, O., Malthièry, Y., Stepien, G. J. Bioenerg. Biomembr. (2005)
- Mitochondrial abnormalities in inclusion-body myositis. Oldfors, A., Moslemi, A.R., Jonasson, L., Ohlsson, M., Kollberg, G., Lindberg, C. Neurology (2006)
- The human skeletal muscle adenine nucleotide translocator gene maps to chromosome 4q35 in the region of the facioscapulohumeral muscular dystrophy locus. Wijmenga, C., Winokur, S.T., Padberg, G.W., Skraastad, M.I., Altherr, M.R., Wasmuth, J.J., Murray, J.C., Hofker, M.H., Frants, R.R. Hum. Genet. (1993)
- POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions. Di Fonzo, A., Bordoni, A., Crimi, M., Sara, G., Del Bo, R., Bresolin, N., Comi, G.P. Hum. Mutat. (2003)
- Mass spectrometric mapping of ion channel proteins (porins) and identification of their supramolecular membrane assembly. Bühler, S., Michels, J., Wendt, S., Rück, A., Brdiczka, D., Welte, W., Przybylski, M. Proteins (1998)
- Oral creatine supplementation decreases plasma markers of adenine nucleotide degradation during a 1-h cycle test. Bellinger, B.M., Bold, A., Wilson, G.R., Noakes, T.D., Myburgh, K.H. Acta Physiol. Scand. (2000)