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BCHE  -  butyrylcholinesterase

Bos taurus

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Disease relevance of BCHE


High impact information on BCHE


Chemical compound and disease context of BCHE


Biological context of BCHE


Anatomical context of BCHE

  • Affinity and carbamylation rate constants of propoxur in reaction with erythrocyte and serum cholinesterase [15].
  • Km and vmax values are given for the hydrolytic activity of porcine liver carboxylic ester hydrolase, wheat germ lipase, candida cylindracea lipase, hog kidney acylase I, and bovine pancreas alpha-chymotrypsin, while others (acetylesterase, trypsin, and cholinesterase) were studied qualitatively [16].
  • ACh content in the culture medium after 24 h of incubation in the presence of isoflurophate, a nonspecific cholinesterase inhibitor, was about 16 times higher than that in endothelial cells, indicating that ACh synthesized inside the cells was released rapidly [17].
  • The cholinesterase activity among erythrocytes, plasma, and cerebrospinal fluid of these species was also compared statistically [18].
  • Five weeks later, the bull had gained weight, the blood cholinesterase activity was 70% of normal, and the results of a semen evaluation indicated he was a satisfactory potential breeder [19].

Associations of BCHE with chemical compounds


Other interactions of BCHE


Analytical, diagnostic and therapeutic context of BCHE


  1. Iodinated contrast agents: effect on acetylcholine hydrolase. In vitro study. Guidollet, J., Louisot, P., Amiel, M., Limam, K. Investigative radiology. (1988) [Pubmed]
  2. Triaryl phosphate poisoning in cattle. Beck, B.E., Wood, C.D., Whenham, G.R. Vet. Pathol. (1977) [Pubmed]
  3. Pulmonary function changes induced by experimental dichlorvos toxicosis in calves. Lekeux, P., Kyavu, A., Clercx, C., Ansay, M. Res. Vet. Sci. (1986) [Pubmed]
  4. Cholinesterase levels in blood plasma and erythrocytes from calves, normal delivering cows and cows suffering from parturient paresis. Forslund, K., Björkman, C., Abrahamsson, M. Acta Vet. Scand. (1983) [Pubmed]
  5. Histochemical characterization of myenteric plexus in domestic fowl small intestine. Csoknya, M., Fekete, E., Gábriel, R., Halasy, K., Benedeczky, I. Zeitschrift für mikroskopisch-anatomische Forschung. (1990) [Pubmed]
  6. Isolation of the secretory form of soluble acetylcholinesterase by using affinity chromatography on edrophonium-Sepharose. Hodgson, A.J., Chubb, I.W. J. Neurochem. (1983) [Pubmed]
  7. The interaction between methylene blue and the cholinergic system. Pfaffendorf, M., Bruning, T.A., Batnik, H.D., van Zwieten, P.A. Br. J. Pharmacol. (1997) [Pubmed]
  8. Pseudocholinesterase-mediated hydrolysis is superior to neostigmine for reversal of mivacurium-induced paralysis in vitro. Yang, H.S., Goudsouzian, N., Martyn, J.A. Anesthesiology (1996) [Pubmed]
  9. The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro. Hunter, A.J., Murray, T.K., Jones, J.A., Cross, A.J., Green, A.R. Br. J. Pharmacol. (1989) [Pubmed]
  10. Carcinogenicity of dichlorvos. Reuber, M.D. Clin. Toxicol. (1981) [Pubmed]
  11. Effect of pretreatment with hepatic microsomal enzyme inducers on the toxicity of diazinon in calves. Abdelsalam, E.B., Ford, E.J. Res. Vet. Sci. (1986) [Pubmed]
  12. Acetylcholinesterase cDNA of the cattle tick, Boophilus microplus: characterisation and role in organophosphate resistance. Baxter, G.D., Barker, S.C. Insect Biochem. Mol. Biol. (1998) [Pubmed]
  13. Kinetics of 13 new cholinesterase inhibitors. Zdrazilová, P., Stĕpánková, S., Komersová, A., Vránová, M., Komers, K., Cegan, A. Z. Naturforsch., C, J. Biosci. (2006) [Pubmed]
  14. Clinical signs and biochemical changes in calves caused by injection of ivermectin. Basudde, C.D. The Veterinary quarterly. (1989) [Pubmed]
  15. Affinity and carbamylation rate constants of propoxur in reaction with erythrocyte and serum cholinesterase. Iverson, F. Biochem. Pharmacol. (1975) [Pubmed]
  16. Fluorimetric assay of hydrolases at longwave excitation and emission wavelengths with new substrates possessing unique water solubility. Wolfbeis, O.S., Koller, E. Anal. Biochem. (1983) [Pubmed]
  17. Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells. Kawashima, K., Watanabe, N., Oohata, H., Fujimoto, K., Suzuki, T., Ishizaki, Y., Morita, I., Murota, S. Neurosci. Lett. (1990) [Pubmed]
  18. A comparison of cholinesterase activity of plasma, erythrocytes, and cerebrospinal fluid of sheep, calves, dogs, swine, and rabbits. Hazelwood, J.C., Heath, G.E. Am. J. Vet. Res. (1976) [Pubmed]
  19. Chlorpyrifos intoxication in a bull. Scarratt, W.K., Blodgett, D.J. J. Am. Vet. Med. Assoc. (1986) [Pubmed]
  20. Mechanism of inhibition in vitro of mammalian acetylcholinesterase and cholinesterase in solutions of 0,0-dimethyl 2,2,2-trichloro-1-hydroxyethyl phosphonate (Trichlorphon). Reiner, E., Krauthacker, B., Simeon, V., Skrinjarić-Spoljar, M. Biochem. Pharmacol. (1975) [Pubmed]
  21. Effects of dichlorvos on blood cholinesterase activities of cattle. Khan, A.A., Coppock, R.W., Schuler, M.M., Lillie, L.E. Am. J. Vet. Res. (1990) [Pubmed]
  22. Effects of T-82, a new quinoline derivative, on cholinesterase activity and extracellular acetylcholine concentration in rat brain. Isoma, K., Ishikawa, M., Ohta, M., Ogawa, Y., Hasegawa, H., Kohda, T., Kamei, J. Jpn. J. Pharmacol. (2002) [Pubmed]
  23. Brain cholinesterases activity in healthy cattle, swine, and sheep and in cattle and sheep exposed to cholinesterase-inhibiting insecticides. Mount, M.E., Oehme, F.W. Am. J. Vet. Res. (1981) [Pubmed]
  24. Cholinesterase activity in the corpus luteum of the sheep and pig. Silver, A. Indian J. Physiol. Pharmacol. (1977) [Pubmed]
  25. Toxicological effects of aerial application of monocrotophos. Rao, R.R., Quadros, F., Mazmudar, R.M., Marathe, M.R., Gangoli, S.D. Arch. Environ. Contam. Toxicol. (1980) [Pubmed]
  26. Systemic control of cattle grubs (Hypoderma spp.) in steers treated with Warbex and weight gains associated with grub control. Khan, M.A., Kozub, G.C. Can. J. Comp. Med. (1981) [Pubmed]
  27. Haemodynamic and neurological responses of ventilated and apnoeic calves to succinyldicholine. Button, C., Bertschinger, H.J., Mülders, M.S. Journal of the South African Veterinary Association. (1981) [Pubmed]
  28. The effect of long-term exposure to anthio on serum esterases and ruminal microorganisms of male calves. Awal, M.D., Saifuddin, A.K. Veterinary and human toxicology. (1994) [Pubmed]
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