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MeSH Review


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Disease relevance of Oligohydramnios


High impact information on Oligohydramnios


Chemical compound and disease context of Oligohydramnios


Biological context of Oligohydramnios


Anatomical context of Oligohydramnios


Gene context of Oligohydramnios

  • The increased adrenomedullin messenger ribonucleic acid expression in the umbilical artery and the elevated adrenomedullin receptor messenger ribonucleic acid expression in the cotyledons of placentas from patients with oligohydramnios may represent a local fetoplacental physiologic adaptive response to vascular compromise [21].
  • Increased echogenicity and renal enlargement are the main ultrasonographic signs of ARPKD; oligohydramnios is characteristic but not always present [25].
  • Severe oligohydramnios in both amniotic sacs appeared as well [26].
  • The finding of oligohydramnios can be associated with fetal anomalies, PROM, uteroplacental insufficiency (eg, growth retardation, postdatism, abruptio placenta, significant maternal illness), abnormalities of twinning, and idiopathic oligohydramnios [27].
  • BACKGROUND: Renal agenesis causes severe oligohydramnios, which results in compression effects, lung hypoplasia, and rapid neonatal death [28].

Analytical, diagnostic and therapeutic context of Oligohydramnios


  1. Renal dysgenesis in a monozygotic twin: association with in utero exposure to indomethacin. Restaino, I., Kaplan, B.S., Kaplan, P., Rosenberg, H.K., Witzleben, C., Roberts, N. Am. J. Med. Genet. (1991) [Pubmed]
  2. Midtrimester diagnosis and anomalies in the dup(22q) syndrome: correlation of aneuploidy with low maternal serum alpha-fetoprotein and oligohydramnios. Johnson, M.P., Greb, A., Goyert, G., Drugan, A., Qureshi, F., Sacks, A.J., Evans, M.I. Am. J. Med. Genet. (1990) [Pubmed]
  3. The association of abnormal alpha-fetoprotein and adverse pregnancy outcome: does increased fetal surveillance affect pregnancy outcome? Huerta-Enochian, G., Katz, V., Erfurth, S. Am. J. Obstet. Gynecol. (2001) [Pubmed]
  4. The effect of the inhibition of prostaglandin synthesis on renal blood flow in fetal sheep. Arnold-Aldea, S.A., Auslender, R.A., Parer, J.T. Am. J. Obstet. Gynecol. (1991) [Pubmed]
  5. Raised maternal serum alpha-fetoprotein, oligohydramnios, and the fetus. Seller, M.J., Child, A.H. Lancet (1980) [Pubmed]
  6. Inhaled nitric oxide in congenital hypoplasia of the lungs due to diaphragmatic hernia or oligohydramnios. Karamanoukian, H.L., Glick, P.L., Zayek, M., Steinhorn, R.H., Zwass, M.S., Fineman, J.R., Morin, F.C. Pediatrics (1994) [Pubmed]
  7. The effect of short-term indomethacin therapy on amniotic fluid volume. Sandruck, J.C., Grobman, W.A., Gerber, S.E. Am. J. Obstet. Gynecol. (2005) [Pubmed]
  8. Reevaluation of the relationship between amniotic fluid volume and perinatal outcome. Ott, W.J. Am. J. Obstet. Gynecol. (2005) [Pubmed]
  9. Paris heat wave and oligohydramnios. Luton, D., Alran, S., Fourchotte, V., Sibony, O., Oury, J.F. Am. J. Obstet. Gynecol. (2004) [Pubmed]
  10. Indomethacin-induced oligohydramnios. Goldenberg, R.L., Davis, R.O., Baker, R.C. Am. J. Obstet. Gynecol. (1989) [Pubmed]
  11. Oligohydramnios associated with prostaglandin synthetase inhibitors in preterm labour. Hendricks, S.K., Smith, J.R., Moore, D.E., Brown, Z.A. British journal of obstetrics and gynaecology. (1990) [Pubmed]
  12. Treatment of oligohydramnios with maternal 1-deamino-[8-D-arginine] vasopressin-induced plasma hypoosmolality. Ross, M.G., Cedars, L., Nijland, M.J., Ogundipe, A. Am. J. Obstet. Gynecol. (1996) [Pubmed]
  13. Oligohydramnios in each sac of a triplet gestation caused by Motrin--fulfilling Kock's postulates. Wiggins, D.A., Elliott, J.P. Am. J. Obstet. Gynecol. (1990) [Pubmed]
  14. Effects of intracervical prostaglandin E2 on fetal heart rate and uterine activity patterns in the presence of oligohydramnios. Larson, J.D., Rayburn, W.F., Turnbull, G.L., Schwartz, W.J., Stanley, J.R., Christensen, H.D. Am. J. Obstet. Gynecol. (1995) [Pubmed]
  15. Elevated maternal serum alpha-fetoprotein, second-trimester oligohydramnios, and pregnancy outcome. Koontz, W.L., Seeds, J.W., Adams, N.J., Johnson, A.M., Cefalo, R.C. Obstetrics and gynecology. (1983) [Pubmed]
  16. Sonographic amniotic fluid measurement and fetal growth retardation: a reappraisal. Patterson, R.M., Prihoda, T.J., Pouliot, M.R. Am. J. Obstet. Gynecol. (1987) [Pubmed]
  17. Effects of indomethacin on corpus luteum function and pregnancy in rhesus monkeys. Manaugh, L.C., Novy, M.J. Fertil. Steril. (1976) [Pubmed]
  18. Prenatal findings in four consecutive pregnancies with fetal Pierson syndrome, a newly defined congenital nephrosis syndrome. Mark, K., Reis, A., Zenker, M. Prenat. Diagn. (2006) [Pubmed]
  19. Elevated alpha-fetoprotein and human chorionic gonadotropin as a marker for placental trisomy 16 in the second trimester? Zimmermann, R., Lauper, U., Streicher, A., Huch, R., Huch, A. Prenat. Diagn. (1995) [Pubmed]
  20. Associations between adverse perinatal outcome and serially obtained second- and third-trimester maternal serum alpha-fetoprotein measurements. Simpson, J.L., Palomaki, G.E., Mercer, B., Haddow, J.E., Andersen, R., Sibai, B., Elias, S. Am. J. Obstet. Gynecol. (1995) [Pubmed]
  21. Localization of messenger ribonucleic acid for adrenomedullin and adrenomedullin receptor in the human placenta in normal pregnancies and pregnancies complicated by oligohydramnios. Apodaca, C.C., Moore, K.H., Rossignol, T.M., Pierce, B., Matej, L.A., Hume, R.F., Calhoun, B.C. Am. J. Obstet. Gynecol. (2000) [Pubmed]
  22. VACTERL association, epidemiologic definition and delineation. Rittler, M., Paz, J.E., Castilla, E.E. Am. J. Med. Genet. (1996) [Pubmed]
  23. Fetal demise with Smith-Lemli-Opitz syndrome confirmed by tissue sterol analysis and the absence of measurable 7-dehydrocholesterol Delta(7)-reductase activity in chorionic villi. Linck, L.M., Hayflick, S.J., Lin, D.S., Battaile, K.P., Ginat, S., Burlingame, T., Gibson, K.M., Honda, M., Honda, A., Salen, G., Tint, G.S., Connor, W.E., Steiner, R.D. Prenat. Diagn. (2000) [Pubmed]
  24. Cloacal dysgenesis sequence: observations in four patients including three fetuses of second trimester gestation. Liang, X., Ioffe, O.B., Sun, C.C. Pediatr. Dev. Pathol. (1998) [Pubmed]
  25. Autosomal recessive polycystic kidney disease. Problems of prenatal diagnosis. Zerres, K., Hansmann, M., Mallmann, R., Gembruch, U. Prenat. Diagn. (1988) [Pubmed]
  26. Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation. Hallak, M., Reiter, A.A., Ayres, N.A., Moise, K.J. Obstetrics and gynecology. (1991) [Pubmed]
  27. Oligohydramnios: problems and treatment. McCurdy, C.M., Seeds, J.W. Semin. Perinatol. (1993) [Pubmed]
  28. Amnioinfusions in renal agenesis. Cameron, D., Lupton, B.A., Farquharson, D., Hiruki, T. Obstetrics and gynecology. (1994) [Pubmed]
  29. Elevated maternal serum alpha-fetoprotein levels and oligohydramnios: poor prognosis for pregnancy outcome. Dyer, S.N., Burton, B.K., Nelson, L.H. Am. J. Obstet. Gynecol. (1987) [Pubmed]
  30. Randomized trial of oral indomethacin and terbutaline sulfate for the long-term suppression of preterm labor. Bivins, H.A., Newman, R.B., Fyfe, D.A., Campbell, B.A., Stramm, S.L. Am. J. Obstet. Gynecol. (1993) [Pubmed]
  31. Outcome of mid-trimester pregnancies complicated by oligohydramnios. Quantitative evaluation of the prognostic value of maternal serum alpha-fetoprotein level. Kovács, T., Csécsei, K., Szabó, M., Veress, L., Tóth, Z., Papp, Z. Journal of perinatal medicine. (1991) [Pubmed]
  32. Maternal hydration for increasing amniotic fluid volume in oligohydramnios and normal amniotic fluid volume. Hofmeyr, G.J., Gülmezoglu, A.M. Cochrane database of systematic reviews (Online) (2002) [Pubmed]
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