Disease relevance of Camellia

• Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats [1].
• The effect of a component of tea (Camellia sinensis) on methicillin resistance, PBP2' synthesis, and beta-lactamase production in Staphylococcus aureus [2].
• Green tea from Camellia sinensis lowers plasma cholesterol in animal models of hypercholesterolemia [3].
• CONCLUSIONS: Brazilian and imported teas made from Camellia sinensis as well as some tea-based beverages are sources of significant amounts of fluoride, and their intake may increase the risk of developing dental fluorosis [4].
• Antibacterial effect of theaflavin, polyphenon 60 (Camellia sinensis) and Euphorbia hirta on Shigella spp.--a cell culture study [5].

High impact information on Camellia

• Carcinogenicity of Camellia sinensis (tea) and some tannin-containing folk medicinal herbs administered subcutaneously in rats [6].
• Epicatechin, a major polyphenol from Camellia sinenesis, also improved graft function and decreased enzyme release, histopathologic changes, and free radical formation [7].
• Adipocyte apoptosis has also been induced in vitro using tumor necrosis factor-alpha (TNF-alpha), (-)-epigallocatechin gallate (EGCG) from Camellia sinensis and ajoene, from Allium sativum [8].
• Chemoprotection: a review of the potential therapeutic antioxidant properties of green tea (Camellia sinensis) and certain of its constituents [9].
• An ethyl acetate fraction from Camellia sinensis green tea leaves, which contains most of the polyphenolic compounds and the maximal trypanocidal activity, was obtained by fractionation of the aqueous extract with organic solvents [10].

Biological context of Camellia

• Extracts of tea (Camellia sinensis) can reverse methicillin resistance in methicillin-resistant Staphylococcus aureus (MRSA) and also, to some extent, penicillin resistance in beta-lactamase-producing S. aureus [2].
• The STS-based markers developed in this study will be very useful in future mapping, population genetics and fingerprinting studies of this important crop species and other Camellia species, as the primers have also proven successful in the three other subgenera of this genus [11].
• ABA associated biochemical changes during somatic embryo development in Camellia sinensis (L.) O. Kuntze [12].
• Exobasidium vexans infection of Camellia sinensis increased 2,3-cis isomerisation and gallate esterification of proanthocyanidins [13].
• OBJECTIVE: The objective of this study was to test an herbal supplement containing black tea (the fully oxidized form of Camellia sinensis) and caffeine for stimulation of thermogenesis [14].

Anatomical context of Camellia

• Camelliatannin D (1), a new complex tannin which inhibits Ca release from mouse calvaria, was isolated from the leaves and fruits of Camellia japonica L [15].
• Cytotoxic and apoptogenic effect of tea (Camellia sinensis var. assamica) root extract (TRE) and two of its steroidal saponins TS1 and TS2 on human leukemic cell lines K562 and U937 and on cells of CML and ALL patients [16].

Associations of Camellia with chemical compounds

• This study investigated if antioxidant polyphenols from Camellia sinenesis (green tea) prevent failure of fatty grafts from ethanol-treated rats [1].
• Metabolism of methionine and biosynthesis of caffeine in the tea plant (Camellia sinensis L.) [17].
• The cholesterol dynamics were compared in rats fed diets containing either camellia oil or partially hydrogenated corn oil as a source of cis- and trans-octadecenoate, respectively [18].
• The activity was also regulated by the degree of unsaturation of dietary fats; when safflower oil, camellia oil or tristearin were fed at the 10% level for 18 days, the higher the unsaturation, the lower the activity [19].
• This was particularly marked with tricaprylin, trilaurin, and camellia oil [20].

Gene context of Camellia

• Green tea (Camellia sinensis) extract does not alter cytochrome p450 3A4 or 2D6 activity in healthy volunteers [21].
• The objective of this study was to assess the influence of a decaffeinated green tea (DGT; Camellia sinensis) extract on the activity of the drug-metabolizing enzymes cytochrome P-450 2D6 and 3A4 [21].
• Purification and partial characterization of a low temperature responsive Mn-SOD from tea (Camellia sinensis (L.) O. Kuntze) [22].
• Inhibition of passive cutaneous anaphylaxis by compounds of Camellia sinensis [23].
• Three full-length cDNAs (CHS1, CHS2 and CHS3) encoding chalcone synthase (CHS; EC 2.3.1.74) were isolated from young leaves of Camellia sinensis [24].

Analytical, diagnostic and therapeutic context of Camellia

• Electrofocusing of methanolic extracts for identification of individual flavonol biomolecules in Camellia species [25].
• High-speed countercurrent chromatography (HSCCC) was applied to the separation of polyphenols from tea leaves (Camellia sinensis L.). The capability of HSCCC to isolate pure tea polyphenols from complex mixtures on a preparative scale was demonstrated for catechins, flavonol glycosides, proanthocyanidins, and strictinin from green and black tea [26].
• Three olean-12-ene type triterpenoid saponins, named TR-saponins A, B and C, were isolated as methyl esters from tea roots (Camellia sinesis var. assamica) after treatment with diazomethane [27].

References