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MeSH Review

Body Height

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Disease relevance of Body Height

  • L3 BMD correlated with both the body height (r = 0.335, p less than 0.0001) and the body weight (r = 0.340, p less than 0.0001) [1].
  • RESULTS: Within this group of engine drivers, age, family history of myocardial infarction, systolic blood pressure and low body height were independent predictors of myocardial infarction, but diabetes, elevated serum cholesterol and smoking were not [2].
  • KET/BM had a significant effect on walking speed after controlling for number of chronic conditions, balance, use of walking aid, joint pain, age, and body height and mass [3].
  • WPA, BMD, body height, height gain, weight, weight gain, dietary polyunsaturated fat and sodium were correlated with delta BMD [4].
  • The results obtained were as follows: (1) Among the six subjects, inhibition of maxillary forward growth was found in four subjects at ages before the maximum pubertal growth in body height occurred, resulting from occlusal interference of anterior cross bite [5].

Psychiatry related information on Body Height

  • After adjustment by analysis of covariance for differences between the subject groups in body height, age and sex distribution, significantly (P less than 0.001) lower concentrations of 5-HIAA and HVA were found in the melancholia patients than in the controls [6].

High impact information on Body Height

  • After adjustment for differences in body height and age between controls and patients, the difference in 5-HIAA level became even more marked [7].
  • Blood hemoglobin concentration was positively correlated with relative body height and with serum IGF-I and IGFBP-3 levels (P = .001 to .02), but not with the concentrations of EPO [8].
  • Mean body height decreased by 0.57 inches in the observation group and .06 inches in the gallium nitrate group [9].
  • Analysis of covariance was performed to calculate mean values of BUA, OC, and DPD/Cr(urine) based on the specified categories of Hcy and vitamin B12 and adjusted for several confounders (potential confounders were age, sex, body weight, body height, current smoking [yes/no], mobility, cognition) [10].
  • METHOD: Participants were 1,103 girls initially assessed in grades 6-9 in school districts in Arizona and California. Each year, students completed the McKnight Risk Factor Survey, had body height and weight measured, and underwent a structured clinical interview [11].

Chemical compound and disease context of Body Height


Biological context of Body Height


Anatomical context of Body Height

  • Disease duration was correlated with vertebral body height (P = 0.001) or intervertebral space height (P = 0.02), and lumbar mobility with thorax expansion (P = 0.004); DISH severity was correlated with basal (P = 0.04) and peak (P = 0.01) glucose levels after glucose load [22].
  • No definite correlation was demonstrated with left ventricular, adrenal, or lymph node fatty infiltration, or with hepatic fatty change, body height, age of patient, or blood glucose [23].
  • Spinal cord and vertebral canal sagittal diameter, vertebral body height at C2 to 5, body length at C3 to 5, and dorsal spine length of C2 were measured on lateral views [24].
  • The most evident effect of FMRP deficit in sexes combined was in decreasing body height and limb length, and in increasing head height and the degree of connective tissue involvement (measured by the middle finger extension angle) [25].

Associations of Body Height with chemical compounds

  • It was found that these groups did not differ in concentrations of 5-HIAA or HVA, at least not when values were corrected for age, sex, and body height [26].
  • No significant relationships were found between substance P levels and age, sex or body height [27].
  • Among the other factors studied, body height contributed most to the variance in both 5-HIAA and HVA concentrations; the levels of MHPG increased with age [28].
  • Carboplatin clearance was significantly related to creatinine clearance and body height, explaining 73% of the interindividual variability [29].
  • A significant negative correlation (-0.45) between body height and maximum nocturnal serum melatonin level was found [30].

Gene context of Body Height

  • Growth hormone (GH) has long been known to be a primary determinant of body height and an important regulator of body metabolism, yet the cellular and molecular bases for these effects of GH are only beginning to be understood [31].
  • After six-month treatment with recombinant human growth hormone (rhGH), serum level of IGFBP-3 in 59 GHD significantly increased from 1.3 +/- 0.7 mg/L to 2.7 +/- 0.9 mg/L, accompanied by an increase of body heights, growth velocities and serum level of IGF-1 [32].
  • A standard dose of 2% mepivacaine with adrenaline, 5, (0.1 ml per cm body height) was given and the patients' ability to discriminate stimuli within dermatomes T8, T10, T12, L2, L4 and S1 was investigated at five min intervals for 30 min after injection [33].
  • IGF-1 levels were correlated with body height (P=0.001, r=0.223), body weight (P=0.002,r=-0.188) and BMI (P=0.039, r=0.128) [34].
  • These results suggest that DNA sequence variation in the MC4R locus may contribute to the gain in body height from childhood to adulthood [35].

Analytical, diagnostic and therapeutic context of Body Height


  1. Quantification of bone mineral content using dual-photon absorptiometry in a normal Japanese population. Hagiwara, S., Miki, T., Nishizawa, Y., Ochi, H., Onoyama, Y., Morii, H. J. Bone Miner. Res. (1989) [Pubmed]
  2. Risk factors for myocardial infarction among Swedish railway engine drivers during 10 years follow-up. Piros, S., Karlehagen, S., Lappas, G., Wilhelmsen, L. Journal of cardiovascular risk. (2000) [Pubmed]
  3. Association of muscle strength with maximum walking speed in disabled older women. Rantanen, T., Guralnik, J.M., Izmirlian, G., Williamson, J.D., Simonsick, E.M., Ferrucci, L., Fried, L.P. American journal of physical medicine & rehabilitation / Association of Academic Physiatrists. (1998) [Pubmed]
  4. Physical activity and dietary constituents as predictors of forearm cortical and trabecular bone gain in healthy children and adolescents: a prospective study. Gunnes, M., Lehmann, E.H. Acta Paediatr. (1996) [Pubmed]
  5. Individual growth in Class III malocclusions and its relationship to the chin cap effects. Ishikawa, H., Nakamura, S., Kim, C., Iwasaki, H., Satoh, Y., Yoshida, S. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. (1998) [Pubmed]
  6. CSF monoamine metabolites in melancholia. Asberg, M., Bertilsson, L., Mårtensson, B., Scalia-Tomba, G.P., Thorén, P., Träskman-Bendz, L. Acta psychiatrica Scandinavica. (1984) [Pubmed]
  7. Monoamine metabolites in CSF and suicidal behavior. Träskman, L., Asberg, M., Bertilsson, L., Sjöstrand, L. Arch. Gen. Psychiatry (1981) [Pubmed]
  8. Hemoglobin level is linked to growth hormone-dependent proteins in short children. Vihervuori, E., Virtanen, M., Koistinen, H., Koistinen, R., Seppälä, M., Siimes, M.A. Blood (1996) [Pubmed]
  9. Low-dose gallium nitrate for prevention of osteolysis in myeloma: results of a pilot randomized study. Warrell, R.P., Lovett, D., Dilmanian, F.A., Schneider, R., Heelan, R.T. J. Clin. Oncol. (1993) [Pubmed]
  10. Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. Dhonukshe-Rutten, R.A., Pluijm, S.M., de Groot, L.C., Lips, P., Smit, J.H., van Staveren, W.A. J. Bone Miner. Res. (2005) [Pubmed]
  11. Risk factors for the onset of eating disorders in adolescent girls: results of the McKnight longitudinal risk factor study. The McKnight Investigators, n.u.l.l. The American journal of psychiatry. (2003) [Pubmed]
  12. Serum albumin is a strong predictor of death in chronic dialysis patients. Iseki, K., Kawazoe, N., Fukiyama, K. Kidney Int. (1993) [Pubmed]
  13. Estimation of cytochrome P-450 CYP1A2 activity in 863 healthy Caucasians using a saliva-based caffeine test. Tantcheva-Poór, I., Zaigler, M., Rietbrock, S., Fuhr, U. Pharmacogenetics (1999) [Pubmed]
  14. Role of sex steroids in the regulation of bone morphology in men. The MINOS study. Szulc, P., Uusi-Rasi, K., Claustrat, B., Marchand, F., Beck, T.J., Delmas, P.D. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. (2004) [Pubmed]
  15. Inconsistent associations among anthropometric measurements in elderly Dutch men and women. Minten, V.K., Löwik, M.R., Deurenberg, P., Kok, F.J. Journal of the American Dietetic Association. (1991) [Pubmed]
  16. Serum hormones in boys prenatally exposed to polychlorinated biphenyls and dibenzofurans. Hsu, P.C., Lai, T.J., Guo, N.W., Lambert, G.H., Leon Guo, Y. J. Toxicol. Environ. Health Part A (2005) [Pubmed]
  17. Bone mineral density, body height, and vitamin D receptor gene polymorphism in middle-aged men. Remes, T., Väisänen, S.B., Mahonen, A., Huuskonen, J., Kröger, H., Jurvelin, J.S., Rauramaa, R. Ann. Med. (2005) [Pubmed]
  18. Segmental bioelectrical impedance analysis: theory and application of a new technique. Organ, L.W., Bradham, G.B., Gore, D.T., Lozier, S.L. J. Appl. Physiol. (1994) [Pubmed]
  19. Limitations concerning the use in children of the relationship between plasma creatinine and body height to derive glomerular filtration rate. Evans, G.O., Griffiths, P.D. Ann. Clin. Biochem. (1981) [Pubmed]
  20. Use of a toxicokinetic model in the analysis of cancer mortality in relation to the estimated absorbed dose of dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD). Salvan, A., Thomaseth, K., Bortot, P., Sartori, N. Sci. Total Environ. (2001) [Pubmed]
  21. Effects of nocloprost clathrate on absorption of acetylsalicylic acid. Siegmund, W., Zschiesche, M., Franke, G., Amon, I. International journal of clinical pharmacology and therapeutics. (1994) [Pubmed]
  22. Acromegalic axial arthropathy: a clinical case-control study. Scarpa, R., De Brasi, D., Pivonello, R., Marzullo, P., Manguso, F., Sodano, A., Oriente, P., Lombardi, G., Colao, A. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  23. Lipohyperplasia of the ileocecal valve. Tawfik, O.W., McGregor, D.H. Am. J. Gastroenterol. (1992) [Pubmed]
  24. Relationship of cervical spinal cord diameter to vertebral dimensions: a radiographic study of normal dogs. Fourie, S.L., Kirberger, R.M. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. (1999) [Pubmed]
  25. Relationship of deficits of FMR1 gene specific protein with physical phenotype of fragile X males and females in pedigrees: a new perspective. Loesch, D.Z., Huggins, R.M., Bui, Q.M., Taylor, A.K., Hagerman, R.J. Am. J. Med. Genet. A (2003) [Pubmed]
  26. 5-HIAA and HVA in CSF in patients with idiopathic pain disorders. Almay, B.G., Häggendal, J., von Knorring, L., Oreland, L. Biol. Psychiatry (1987) [Pubmed]
  27. Substance P in CSF of patients with chronic pain syndromes. Almay, B.G., Johansson, F., Von Knorring, L., Le Grevés, P., Terenius, L. Pain (1988) [Pubmed]
  28. Neurotransmission and the experience of low back pain; no association between CSF monoamine metabolites and pain. Hyyppä, M.T., Scheinin, H., Alaranta, H., Hurme, M., Lahtela, K., Scheinin, M. Pain (1985) [Pubmed]
  29. Individualised dosing strategy for high-dose carboplatin in patients with germ cell cancer. Kloft, C., Siegert, W., Jaehde, U. Br. J. Cancer (2003) [Pubmed]
  30. Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects. Beck-Friis, J., von Rosen, D., Kjellman, B.F., Ljunggren, J.G., Wetterberg, L. Psychoneuroendocrinology (1984) [Pubmed]
  31. SH2-B and SIRP: JAK2 binding proteins that modulate the actions of growth hormone. Carter-Su, C., Rui, L., Stofega, M.R. Recent Prog. Horm. Res. (2000) [Pubmed]
  32. Diagnostic value of serum insulin-like growth factor binding protein-3 in children with or without growth hormone deficiency. Qin, S., Shi, Y., Deng, J. Chin. Med. Sci. J. (2002) [Pubmed]
  33. Assessment of sensory block in epidural anaesthesia by electric stimulation. Dyhre, H., Renck, H., Andersson, C. Acta anaesthesiologica Scandinavica. (1994) [Pubmed]
  34. Age dependency of serum insulin - like growth factor (IGF)-1 in healthy Turkish adolescents and adults. Tiryakioğlu, O., Kadiolgu, P., Canerolgu, N.U., Hatemi, H. Indian journal of medical sciences. (2003) [Pubmed]
  35. MC4R marker associated with stature in children and young adults: a longitudinal study. Santoro, N., Rankinen, T., Pérusse, L., Loos, R.J., Bouchard, C. Journal of pediatric endocrinology & metabolism : JPEM. (2005) [Pubmed]
  36. Geographical clustering and maintained health in individuals harbouring the mutation for Greenland familial cholestasis: A population-based study. Andersen, S., Okkels, H., Krarup, H., Laurberg, P. Scand. J. Gastroenterol. (2006) [Pubmed]
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