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MeSH Review

Glomerular Mesangium

 
 
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Disease relevance of Glomerular Mesangium

 

High impact information on Glomerular Mesangium

  • In the course of glomerular development, small groups of PDGF-Rbeta and desmin-expressing cells collected in the 'S'-shaped and early cup-shaped vesicles, and at later stages such cells were found in the glomerular mesangium [6].
  • Among non-central nervous system tissues and tumors, GMEM was found by peroxidase-antiperoxidase immunohistology in normal liver sinusoids, spleen red pulp sinusoids, kidney medullary tubule interstitium, and glomerular mesangium and in association with vascular and stromal elements of several undifferentiated tumors [7].
  • Western blot analysis demonstrated increased PKC beta in diabetic animals, localized by immunofluorescence to the glomerular mesangium [8].
  • MCBM width did not correlate with age, duration of diabetes, creatinine clearance, urinary albumin excretion, or fractional volume of the glomerular mesangium [9].
  • Uptake of polyvinyl alcohol by macrophages in the glomerular mesangium of rats. Histologic and functional studies [10].
 

Biological context of Glomerular Mesangium

 

Anatomical context of Glomerular Mesangium

 

Associations of Glomerular Mesangium with chemical compounds

 

Gene context of Glomerular Mesangium

References

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  8. Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. Kelly, D.J., Zhang, Y., Hepper, C., Gow, R.M., Jaworski, K., Kemp, B.E., Wilkinson-Berka, J.L., Gilbert, R.E. Diabetes (2003) [Pubmed]
  9. Relationship of muscle capillary basement membrane to renal structure and function in diabetes mellitus. Ellis, E.N., Mauer, S.M., Goetz, F.C., Sutherland, D.E., Steffes, M.W. Diabetes (1986) [Pubmed]
  10. Uptake of polyvinyl alcohol by macrophages in the glomerular mesangium of rats. Histologic and functional studies. Sterzel, R.B., Eisenbach, G.M., Seiler, M.W., Hoyer, J.R. Am. J. Pathol. (1983) [Pubmed]
  11. Simvastatin inhibits the cellular signaling and proliferative action of arginine vasopressin in cultured rat glomerular mesangial cells. Ishikawa, S., Kawasumi, M., Saito, T. Endocrinology (1995) [Pubmed]
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  14. Monoclonal antibodies to human glomerular antigens. Nakamura, T., Oite, T., Kazama, T., Suzuki, S., Orikasa, M., Arakawa, M., Shimizu, F. Virchows Archiv. A, Pathological anatomy and histopathology. (1988) [Pubmed]
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  16. Localization of decay accelerating factor in normal and diseased kidneys. Cosio, F.G., Sedmak, D.D., Mahan, J.D., Nahman, N.S. Kidney Int. (1989) [Pubmed]
  17. Three-dimensional matrix primes mesangial cells to down-regulation of alpha-smooth muscle actin via deactivation of CArG box elements. Kitamura, M., Ishikawa, Y. Kidney Int. (1998) [Pubmed]
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  23. Neutral proteinase activity produced in vitro by cells of the glomerular mesangium. Lovett, D.H., Sterzel, R.B., Kashgarian, M., Ryan, J.L. Kidney Int. (1983) [Pubmed]
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