Gene Review:
Des - desmin
Mus musculus
Synonyms:
Desmin
- Extensive induction of important mediators of fibrosis and dystrophic calcification in desmin-deficient cardiomyopathy. Mavroidis, M., Capetanaki, Y. Am. J. Pathol. (2002)
- Mouse mammary tumors induced by medroxyprogesterone acetate: immunohistochemistry and hormonal receptors. Molinolo, A.A., Lanari, C., Charreau, E.H., Sanjuan, N., Pasqualini, C.D. J. Natl. Cancer Inst. (1987)
- Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages. Bär, H., Mücke, N., Kostareva, A., Sjöberg, G., Aebi, U., Herrmann, H. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. Weisleder, N., Taffet, G.E., Capetanaki, Y. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene. Dalakas, M.C., Park, K.Y., Semino-Mora, C., Lee, H.S., Sivakumar, K., Goldfarb, L.G. N. Engl. J. Med. (2000)
- Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation. Frock, R.L., Kudlow, B.A., Evans, A.M., Jameson, S.A., Hauschka, S.D., Kennedy, B.K. Genes Dev. (2006)
- Defects in nuclear structure and function promote dilated cardiomyopathy in lamin A/C-deficient mice. Nikolova, V., Leimena, C., McMahon, A.C., Tan, J.C., Chandar, S., Jogia, D., Kesteven, S.H., Michalicek, J., Otway, R., Verheyen, F., Rainer, S., Stewart, C.L., Martin, D., Feneley, M.P., Fatkin, D. J. Clin. Invest. (2004)
- Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis. Miyazaki, Y., Araki, K., Vesin, C., Garcia, I., Kapanci, Y., Whitsett, J.A., Piguet, P.F., Vassalli, P. J. Clin. Invest. (1995)
- Blockade of kit signaling induces transdifferentiation of interstitial cells of cajal to a smooth muscle phenotype. Torihashi, S., Nishi, K., Tokutomi, Y., Nishi, T., Ward, S., Sanders, K.M. Gastroenterology (1999)
- Monoclonal antibody P-31 recognizes a novel intermediate filament-associated protein (p250) in rat podocytes. Kurihara, H., Sunagawa, N., Kobayashi, T., Kimura, K., Takasu, N., Shike, T. Am. J. Physiol. (1998)
- The stellate cells phenotypic transformation in the CCl4- injured liver fibrosis of ICR mice: their desmin immunoreactivity and vitamin A storage. Lukita-Atmadja, W., Subowo, n.u.l.l. The Kobe journal of medical sciences. (1993)
- Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle. Li, Z., Mericskay, M., Agbulut, O., Butler-Browne, G., Carlsson, L., Thornell, L.E., Babinet, C., Paulin, D. J. Cell Biol. (1997)
- Inhibition of desmin expression blocks myoblast fusion and interferes with the myogenic regulators MyoD and myogenin. Li, H., Choudhary, S.K., Milner, D.J., Munir, M.I., Kuisk, I.R., Capetanaki, Y. J. Cell Biol. (1994)
- An E box in the desmin promoter cooperates with the E box and MEF-2 sites of a distal enhancer to direct muscle-specific transcription. Li, H., Capetanaki, Y. EMBO J. (1994)
- Myogenesis in the mouse embryo: differential onset of expression of myogenic proteins and the involvement of titin in myofibril assembly. Fürst, D.O., Osborn, M., Weber, K. J. Cell Biol. (1989)
- Expression of myogenic regulatory factors during the development of mouse tongue striated muscle. Yamane, A., Mayo, M., Shuler, C., Crowe, D., Ohnuki, Y., Dalrymple, K., Saeki, Y. Arch. Oral Biol. (2000)
- Assignment of the mouse desmin gene to chromosome 1 band C3. Li, Z.L., Mattei, M.G., Mattei, J.F., Paulin, D. Genet. Res. (1990)
- Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning. Pelloux, S., Robillard, J., Ferrera, R., Bilbaut, A., Ojeda, C., Saks, V., Ovize, M., Tourneur, Y. Prog. Biophys. Mol. Biol. (2006)
- A proximal promoter element in the hamster desmin upstream regulatory region is responsible for activation by myogenic determination factors. van de Klundert, F.A., Jansen, H.J., Bloemendal, H. J. Biol. Chem. (1994)
- Bone marrow-derived progenitor cells contribute to experimental choroidal neovascularization. Espinosa-Heidmann, D.G., Caicedo, A., Hernandez, E.P., Csaky, K.G., Cousins, S.W. Invest. Ophthalmol. Vis. Sci. (2003)
- Association of calponin with desmin intermediate filaments. Mabuchi, K., Li, B., Ip, W., Tao, T. J. Biol. Chem. (1997)
- Tissue-specific expression of a vimentin--desmin hybrid gene in transgenic mice. Krimpenfort, P.J., Schaart, G., Pieper, F.R., Ramaekers, F.C., Cuypers, H.T., van den Heuvel, R.M., Vree Egberts, W.T., van Eys, G.J., Berns, A., Bloemendal, H. EMBO J. (1988)
- Differences in the distribution of synemin, paranemin, and plectin in skeletal muscles of wild-type and desmin knock-out mice. Carlsson, L., Li, Z.L., Paulin, D., Price, M.G., Breckler, J., Robson, R.M., Wiche, G., Thornell, L.E. Histochem. Cell Biol. (2000)
- Nestin is expressed during development and in myotendinous and neuromuscular junctions in wild type and desmin knock-out mice. Carlsson, L., Li, Z., Paulin, D., Thornell, L.E. Exp. Cell Res. (1999)
- Transforming growth factor alpha up-regulates desmin expression during embryonic mouse tongue myogenesis. Yamane, A., Bringas, P., Mayo, M.L., Amano, O., Takahashi, K., Vo, H., Shum, L., Slavkin, H.C. Dev. Dyn. (1998)
- Intrinsic differences in MyoD and myogenin expression between primary cultures of SJL/J and BALB/C skeletal muscle. Maley, M.A., Fan, Y., Beilharz, M.W., Grounds, M.D. Exp. Cell Res. (1994)
- Lhx2 is expressed in the septum transversum mesenchyme that becomes an integral part of the liver and the formation of these cells is independent of functional Lhx2. Kolterud, A., Wandzioch, E., Carlsson, L. Gene Expr. Patterns (2004)
- Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Hellström, M., Kalén, M., Lindahl, P., Abramsson, A., Betsholtz, C. Development (1999)
- Dysmorphogenesis of kidney cortical peritubular capillaries in angiopoietin-2-deficient mice. Pitera, J.E., Woolf, A.S., Gale, N.W., Yancopoulos, G.D., Yuan, H.T. Am. J. Pathol. (2004)
- Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. LeCouter, J.E., Kablar, B., Whyte, P.F., Ying, C., Rudnicki, M.A. Development (1998)
- Smooth muscle differentiation and cell turnover in mouse detrusor development. Smeulders, N., Woolf, A.S., Wilcox, D.T. J. Urol. (2002)
- Mechanical properties and structure of carotid arteries in mice lacking desmin. Lacolley, P., Challande, P., Boumaza, S., Cohuet, G., Laurent, S., Boutouyrie, P., Grimaud, J.A., Paulin, D., Lamazière, J.M., Li, Z. Cardiovasc. Res. (2001)
- Excessive microvascular adaptation to changes in blood flow in mice lacking gene encoding for desmin. Loufrani, L., Li, Z., Lévy, B.I., Paulin, D., Henrion, D. Arterioscler. Thromb. Vasc. Biol. (2002)
- Mechanical function of intermediate filaments in arteries of different size examined using desmin deficient mice. Wede, O.K., Löfgren, M., Li, Z., Paulin, D., Arner, A. J. Physiol. (Lond.) (2002)