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MeSH Review

Arthritis, Psoriatic

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Disease relevance of Arthritis, Psoriatic


High impact information on Arthritis, Psoriatic


Chemical compound and disease context of Arthritis, Psoriatic


Biological context of Arthritis, Psoriatic


Anatomical context of Arthritis, Psoriatic


Gene context of Arthritis, Psoriatic

  • Primary cultures of FLS from patients with rheumatoid arthritis (RA), psoriatic arthritis, sarcoid arthritis, and undifferentiated arthritis were established [26].
  • Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles [27].
  • The CD8 alphabetaT cell receptor repertoire in joint fluid of individuals with active psoriatic arthritis contained an average of 32 major oligoclonal expansions in many variable genes of the TCR beta chain (BV) families, as shown by beta-chain CDR3 length analysis [28].
  • Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis [29].
  • The increase in KIR2DS1 has also been observed in psoriatic arthritis, another HLA-Cw6-associated disease (Martin et al, 2002) [30].

Analytical, diagnostic and therapeutic context of Arthritis, Psoriatic


  1. Histocompatibility alloantigens in psoriasis and psoriatic arthritis. Evidence for the influence of multiple genes in the major histocompatibility complex. Murray, C., Mann, D.L., Gerber, L.N., Barth, W., Perlmann, S., Decker, J.L., Nigra, T.P. J. Clin. Invest. (1980) [Pubmed]
  2. Immunoelectrophoretic assay for synovial fluid C3 with correction for synovial fluid globulin. Hasselbacher, P. Arthritis Rheum. (1979) [Pubmed]
  3. The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis. Lohmander, L.S., Neame, P.J., Sandy, J.D. Arthritis Rheum. (1993) [Pubmed]
  4. Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis. Ho, P., Bruce, I.N., Silman, A., Symmons, D., Newman, B., Young, H., Griffiths, C.E., John, S., Worthington, J., Barton, A. Arthritis Rheum. (2005) [Pubmed]
  5. Production of agglutinators and rheumatoid factors in plasma cells of rheumatoid and nonrheumatoid synovial tissues. Fehr, K., Velvart, M., Rauber, M., Knöpfel, M., Baici, A., Salgam, P., Böni, A. Arthritis Rheum. (1981) [Pubmed]
  6. Levamisol in psoriatic arthritis. Rosenthal, M., Trabert, U. N. Engl. J. Med. (1976) [Pubmed]
  7. CD4+ CD7- CD28- T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. Schmidt, D., Goronzy, J.J., Weyand, C.M. J. Clin. Invest. (1996) [Pubmed]
  8. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial. Mease, P.J., Goffe, B.S., Metz, J., VanderStoep, A., Finck, B., Burge, D.J. Lancet (2000) [Pubmed]
  9. CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis. Rahman, P., Bartlett, S., Siannis, F., Pellett, F.J., Farewell, V.T., Peddle, L., Schentag, C.T., Alderdice, C.A., Hamilton, S., Khraishi, M., Tobin, Y., Hefferton, D., Gladman, D.D. Am. J. Hum. Genet. (2003) [Pubmed]
  10. Rheumatic diseases: the effects of inflammation on bone. Walsh, N.C., Crotti, T.N., Goldring, S.R., Gravallese, E.M. Immunol. Rev. (2005) [Pubmed]
  11. Randomized, double-blind, placebo controlled trial of low-dose pulse methotrexate in psoriatic arthritis. Willkens, R.F., Williams, H.J., Ward, J.R., Egger, M.J., Reading, J.C., Clements, P.J., Cathcart, E.S., Samuelson, C.O., Solsky, M.A., Kaplan, S.B. Arthritis Rheum. (1984) [Pubmed]
  12. Sulfasalazine in psoriatic arthritis: a new or established indication? Goupille, P., Valat, J.P. Arthritis Rheum. (1996) [Pubmed]
  13. Ibuprofen in psoriatic arthritis. Smith, D.L., Regan, M.G. Arthritis Rheum. (1980) [Pubmed]
  14. Drug-induced peripheral neuropathy in a patient with psoriatic arthritis. Rothenberg, R.J., Sufit, R.L. Arthritis Rheum. (1987) [Pubmed]
  15. Oral 2-chlorodeoxyadenosine in psoriatic arthritis. A preliminary report. Eibschutz, B., Baird, S.M., Weisman, M.H., Amox, D.G., Spellman, M., Piacquadio, D., Carrera, C.J., Carson, D.A. Arthritis Rheum. (1995) [Pubmed]
  16. Mice lacking endogenous major histocompatibility complex class II develop arthritis resembling psoriatic arthritis at an advanced age. Bárdos, T., Zhang, J., Mikecz, K., David, C.S., Glant, T.T. Arthritis Rheum. (2002) [Pubmed]
  17. Allelic variants of drug metabolizing enzymes as risk factors in psoriasis. Richter-Hintz, D., Their, R., Steinwachs, S., Kronenberg, S., Fritsche, E., Sachs, B., Wulferink, M., Tonn, T., Esser, C. J. Invest. Dermatol. (2003) [Pubmed]
  18. Lymphocyte depletion with fludarabine in patients with psoriatic arthritis: clinical and immunological effects. Takada, K., Danning, C.L., Kuroiwa, T., Schlimgen, R., Tassiulas, I.O., Davis, J.C., Yarboro, C.H., Fleisher, T.A., Boumpas, D.T., Illei, G.G. Ann. Rheum. Dis. (2003) [Pubmed]
  19. Assessing periarticular bone mineral density in patients with early psoriatic arthritis or rheumatoid arthritis. Harrison, B.J., Hutchinson, C.E., Adams, J., Bruce, I.N., Herrick, A.L. Ann. Rheum. Dis. (2002) [Pubmed]
  20. HLA-C locus alleles in patients with psoriatic arthritis (PsA). Gladman, D.D., Cheung, C., Ng, C.M., Wade, J.A. Hum. Immunol. (1999) [Pubmed]
  21. V2 regions of 16S ribosomal RNA used as a molecular marker for the species identification of streptococci in peripheral blood and synovial fluid from patients with psoriatic arthritis. Wang, Q., Vasey, F.B., Mahfood, J.P., Valeriano, J., Kanik, K.S., Anderson, B.E., Bridgeford, P.H. Arthritis Rheum. (1999) [Pubmed]
  22. Macrophage-derived cytokine and nuclear factor kappaB p65 expression in synovial membrane and skin of patients with psoriatic arthritis. Danning, C.L., Illei, G.G., Hitchon, C., Greer, M.R., Boumpas, D.T., McInnes, I.B. Arthritis Rheum. (2000) [Pubmed]
  23. Matrix metalloproteinase 9, apoptosis, and vascular morphology in early arthritis. Fraser, A., Fearon, U., Reece, R., Emery, P., Veale, D.J. Arthritis Rheum. (2001) [Pubmed]
  24. Expression of the pro-inflammatory protein S100A12 (EN-RAGE) in rheumatoid and psoriatic arthritis. Foell, D., Kane, D., Bresnihan, B., Vogl, T., Nacken, W., Sorg, C., Fitzgerald, O., Roth, J. Rheumatology (Oxford, England) (2003) [Pubmed]
  25. A comparison of ultrasonography and magnetic resonance imaging in the evaluation of temporomandibular joint involvement in rheumatoid arthritis and psoriatic arthritis. Melchiorre, D., Calderazzi, A., Maddali Bongi, S., Cristofani, R., Bazzichi, L., Eligi, C., Maresca, M., Ciompi, M. Rheumatology (Oxford, England) (2003) [Pubmed]
  26. Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis. O'Hara, R., Murphy, E.P., Whitehead, A.S., FitzGerald, O., Bresnihan, B. Arthritis Rheum. (2004) [Pubmed]
  27. Cutting edge: susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. Martin, M.P., Nelson, G., Lee, J.H., Pellett, F., Gao, X., Wade, J., Wilson, M.J., Trowsdale, J., Gladman, D., Carrington, M. J. Immunol. (2002) [Pubmed]
  28. Psoriatic arthritis joint fluids are characterized by CD8 and CD4 T cell clonal expansions appear antigen driven. Costello, P.J., Winchester, R.J., Curran, S.A., Peterson, K.S., Kane, D.J., Bresnihan, B., FitzGerald, O.M. J. Immunol. (2001) [Pubmed]
  29. Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis. Hüffmeier, U., Reis, A., Steffens, M., Lascorz, J., Böhm, B., Lohmann, J., Wendler, J., Traupe, H., Küster, W., Wienker, T.F., Burkhardt, H. J. Invest. Dermatol. (2006) [Pubmed]
  30. Genetic polymorphisms of killer cell immunoglobulin-like receptors are associated with susceptibility to psoriasis vulgaris. Suzuki, Y., Hamamoto, Y., Ogasawara, Y., Ishikawa, K., Yoshikawa, Y., Sasazuki, T., Muto, M. J. Invest. Dermatol. (2004) [Pubmed]
  31. Low-dose methotrexate kinetics in arthritis. Edelman, J., Biggs, D.F., Jamali, F., Russell, A.S. Clin. Pharmacol. Ther. (1984) [Pubmed]
  32. A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis. Fraser, A.D., van Kuijk, A.W., Westhovens, R., Karim, Z., Wakefield, R., Gerards, A.H., Landewé, R., Steinfeld, S.D., Emery, P., Dijkmans, B.A., Veale, D.J. Ann. Rheum. Dis. (2005) [Pubmed]
  33. Detection of Epstein-Barr virus-encoded small RNA 1 and latent membrane protein 1 in synovial lining cells from rheumatoid arthritis patients. Takei, M., Mitamura, K., Fujiwara, S., Horie, T., Ryu, J., Osaka, S., Yoshino, S., Sawada, S. Int. Immunol. (1997) [Pubmed]
  34. Inflammatory joint disease: a comparison of liposome scanning, bone scanning, and radiography. O'Sullivan, M.M., Powell, N., French, A.P., Williams, K.E., Morgan, J.R., Williams, B.D. Ann. Rheum. Dis. (1988) [Pubmed]
  35. Granisetron (Kytril) suppresses methotrexate-induced nausea and vomiting among patients with inflammatory arthritis and is superior to prochlorperazine (Stemetil). Devlin, J., Wagstaff, K., Arthur, V., Emery, P. Rheumatology (Oxford, England) (1999) [Pubmed]
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