The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Newcastle Disease

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Newcastle Disease


High impact information on Newcastle Disease


Chemical compound and disease context of Newcastle Disease


Biological context of Newcastle Disease


Anatomical context of Newcastle Disease


Gene context of Newcastle Disease

  • Except for a significant reduction in IFN-alpha release stimulated by Newcastle disease virus (NDV), IFN productions induced by other mitogens (phytohemagglutinin, PHA; Concanavalin A, ConA; pokeweed mitogen, PWM) and viral antigens were within normal range [26].
  • SMC treated with poly(I):poly(C) or Newcastle Disease virus elaborated biologically active IFN-beta as well [27].
  • IL-2-induced secretion of mediators was compared with that following stimulation with lipopolisaccharide (LPS; 5 micrograms/ml) or Newcastle disease virus (NDV; 640 HU/ml) [28].
  • To test this hypothesis, L929 cells were infected with Newcastle disease virus (NDV), which led to the induction of IL-15 mRNA and protein expression [29].
  • The independent expression of C or V inhibited the double-stranded (ds) RNA- or Newcastle disease virus (NDV)-induced activation of IRF-3 and NF-kappa B, as well as the IFN-beta promoter [30].

Analytical, diagnostic and therapeutic context of Newcastle Disease


  1. GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction. Moore, K.L., Varki, A., McEver, R.P. J. Cell Biol. (1991) [Pubmed]
  2. Increased sensitivity of SARS-coronavirus to a combination of human type I and type II interferons. Scagnolari, C., Vicenzi, E., Bellomi, F., Stillitano, M.G., Pinna, D., Poli, G., Clementi, M., Dianzani, F., Antonelli, G. Antivir. Ther. (Lond.) (2004) [Pubmed]
  3. Loss ability to produce IFN-alpha in response to HIV-1 as monocytes differentiate into macrophages. Induction through a mechanism independent of double-stranded RNA. Francis, M.L., Fan, X.S., Meltzer, M.S. J. Immunol. (1996) [Pubmed]
  4. Expression of mouse furin in a Chinese hamster cell resistant to Pseudomonas exotoxin A and viruses complements the genetic lesion. Moehring, J.M., Inocencio, N.M., Robertson, B.J., Moehring, T.J. J. Biol. Chem. (1993) [Pubmed]
  5. Cell surface sialic acid influences tumor cell recognition in the mixed lymphocyte reaction. Powell, L.D., Whiteheart, S.W., Hart, G.W. J. Immunol. (1987) [Pubmed]
  6. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Matsuyama, T., Kimura, T., Kitagawa, M., Pfeffer, K., Kawakami, T., Watanabe, N., Kündig, T.M., Amakawa, R., Kishihara, K., Wakeham, A. Cell (1993) [Pubmed]
  7. Virus-induced corticosterone in hypophysectomized mice: a possible lymphoid adrenal axis. Smith, E.M., Meyer, W.J., Blalock, J.E. Science (1982) [Pubmed]
  8. Butylated hydroxytoluene protects chickens exposed to Newcastle disease virus. Brugh, M. Science (1977) [Pubmed]
  9. Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase. Crennell, S., Takimoto, T., Portner, A., Taylor, G. Nat. Struct. Biol. (2000) [Pubmed]
  10. Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Lieberman, A.P., Pitha, P.M., Shin, H.S., Shin, M.L. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  11. Conformational change in a viral glycoprotein during maturation due to disulfide bond disruption. Morrison, T.G., Peeples, M.E., McGinnes, L.W. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  12. Inhibition of protein synthesis stimulates the transcription of human beta-interferon genes in Chinese hamster ovary cells. Ringold, G.M., Dieckmann, B., Vannice, J.L., Trahey, M., McCormick, F. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  13. Methylation of messenger RNA of Newcastle disease virus in vitro by a virion-associated enzyme. Colonno, R.J., Stone, H.O. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  14. Had-1, a uridine 5'-diphosphogalactose transport-defective mutant of mouse mammary tumor cell FM3A: composition of glycolipids, cell growth inhibition by lactosylceramide, and loss of tumorigenicity. Taki, T., Ogura, K., Rokukawa, C., Hara, T., Kawakita, M., Endo, T., Kobata, A., Handa, S. Cancer Res. (1991) [Pubmed]
  15. Lipopolysaccharide inhibits virus-mediated induction of interferon genes by disruption of nuclear transport of interferon regulatory factors 3 and 7. Juang, Y.T., Au, W.C., Lowther, W., Hiscott, J., Pitha, P.M. J. Biol. Chem. (1999) [Pubmed]
  16. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Miyamoto, M., Fujita, T., Kimura, Y., Maruyama, M., Harada, H., Sudo, Y., Miyata, T., Taniguchi, T. Cell (1988) [Pubmed]
  17. Induction of C3 expression in astrocytes is regulated by cytokines and Newcastle disease virus. Rus, H.G., Kim, L.M., Niculescu, F.I., Shin, M.L. J. Immunol. (1992) [Pubmed]
  18. Nucleotide sequence of the phosphoprotein (P) gene of Newcastle disease virus (strain Beaudette C). Daskalakis, S., Menke, J., Stripp, B., Stone, H. Nucleic Acids Res. (1992) [Pubmed]
  19. Multiple regulatory elements are required to direct trophoblast interferon gene expression in choriocarcinoma cells and trophectoderm. Leaman, D.W., Cross, J.C., Roberts, R.M. Mol. Endocrinol. (1994) [Pubmed]
  20. Loss of N-linked glycosylation from the hemagglutinin-neuraminidase protein alters virulence of Newcastle disease virus. Panda, A., Elankumaran, S., Krishnamurthy, S., Huang, Z., Samal, S.K. J. Virol. (2004) [Pubmed]
  21. Translation and membrane insertion of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus. Wilson, C., Gilmore, R., Morrison, T. Mol. Cell. Biol. (1987) [Pubmed]
  22. Aberrant membrane insertion of a cytoplasmic tail deletion mutant of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus. Wilson, C., Gilmore, R., Morrison, T. Mol. Cell. Biol. (1990) [Pubmed]
  23. TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment. Orinska, Z., Bulanova, E., Budagian, V., Metz, M., Maurer, M., Bulfone-Paus, S. Blood (2005) [Pubmed]
  24. Aberrant expression of cytokine genes in peritoneal macrophages from mice infected with LP-BM5 MuLV, a murine model of AIDS. Cheung, S.C., Chattopadhyay, S.K., Hartley, J.W., Morse, H.C., Pitha, P.M. J. Immunol. (1991) [Pubmed]
  25. IFN and virus-inducible expression of an immediate early gene, crg-2/IP-10, and a delayed gene, I-A alpha in astrocytes and microglia. Vanguri, P., Farber, J.M. J. Immunol. (1994) [Pubmed]
  26. Long-term effects of 2'-deoxycoformycin treatment on cytokine production in patients with hairy cell leukemia. Ho, A.D., Männel, D.N., Wulf, G., Kirchner, H., Gundt, A., Trede, I., Rensch, K., Hunstein, W. Leukemia (1990) [Pubmed]
  27. Interferon-beta. A potential autocrine regulator of human vascular smooth muscle cell growth. Palmer, H., Libby, P. Lab. Invest. (1992) [Pubmed]
  28. Exogenous interleukin 2 regulates interleukin 6 and nitric oxide but not interferon gamma and tumor necrosis factor alpha production in bronchoalveolar leukocytes from patients with small cell lung cancer. Cembrzyńska-Nowak, M., Bieńkowska, M., Szklarz, E. Arch. Immunol. Ther. Exp. (Warsz.) (1998) [Pubmed]
  29. Viral activation of interleukin-15 (IL-15): characterization of a virus-inducible element in the IL-15 promoter region. Azimi, N., Shiramizu, K.M., Tagaya, Y., Mariner, J., Waldmann, T.A. J. Virol. (2000) [Pubmed]
  30. C and V proteins of Sendai virus target signaling pathways leading to IRF-3 activation for the negative regulation of interferon-beta production. Komatsu, T., Takeuchi, K., Yokoo, J., Gotoh, B. Virology (2004) [Pubmed]
  31. Determination of the disulfide bond arrangement of Newcastle disease virus hemagglutinin neuraminidase. Correlation with a beta-sheet propeller structural fold predicted for paramyxoviridae attachment proteins. Pitt, J.J., Da Silva, E., Gorman, J.J. J. Biol. Chem. (2000) [Pubmed]
  32. Synthesis of Newcastle disease virus (NDV)-like envelopes in insect cells infected with a recombinant baculovirus expressing the haemagglutinin-neuraminidase of NDV. Nagy, E., Huber, P., Krell, P.J., Derbyshire, J.B. J. Gen. Virol. (1991) [Pubmed]
  33. Biological similarities of rat fibroblast interferon to human and mouse alpha interferons. Davis, C.T., Rusckowski, M., Murasko, D.M. J. Gen. Virol. (1985) [Pubmed]
  34. Newcastle disease virus evolution. II. Lack of gene recombination in generating virulent and avirulent strains. Toyoda, T., Sakaguchi, T., Hirota, H., Gotoh, B., Kuma, K., Miyata, T., Nagai, Y. Virology (1989) [Pubmed]
WikiGenes - Universities